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Seven classes of antiviral agents
The viral epidemics and pandemics have stimulated the development of known and the discovery of novel antiviral agents. About a hundred mono- and...
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Mannose-specific plant and microbial lectins as antiviral agents: A review
Lectins are non-immunological carbohydrate-binding proteins classified on the basis of their structure, origin, and sugar specificity. The binding...
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Investigating antiviral activities of iodine-conjugated organic agents against major viruses infecting pepper in Korea
BackgroundPlant viruses cause economic losses by reducing the quantity and quality of major crops. This issue is a growing concern due to the...
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Novel flavonol derivatives containing benzoxazole as potential antiviral agents: design, synthesis, and biological evaluation
A series of flavonol derivatives containing benzoxazole were designed and synthesized, and the structures of all the target compounds were determined...
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Role of marine natural products in the development of antiviral agents against SARS-CoV-2: potential and prospects
A novel coronavirus, known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has surfaced and caused global concern owing to its...
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Lectins and lectibodies: potential promising antiviral agents
In nature, lectins are widely dispersed proteins that selectively recognize and bind to carbohydrates and glycoconjugates via reversible bonds at...
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Antiviral Activities of Cannabis
Despite the history of scientific evidence regarding plants and their products in prophylactics and therapeutics, their applications in healthcare... -
Purification of an antiviral protein from the seeds of quinoa (Chenopodium quinoa Willd.) and characterization of its antiviral properties
Plant viral pathogens cause damaging diseases in many agriculture systems, and emerging viral infections are a serious threat for providing adequate...
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Plant-derived lignans as potential antiviral agents: a systematic review
Medicinal plants are one of the most important sources of antiviral agents and lead compounds. Lignans are a large class of natural compounds...
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A Review: The Antiviral Activity of Cyclic Peptides
In the design and development of therapeutic agents, macromolecules with restricted structures have stronger competitive edges than linear biological...
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CADD Approaches and Antiviral Drug Discovery
The virus causes an infection that every year threatens the health of people all over the world and costs a lot of money. Even though there are now... -
Cyanometabolites: molecules with immense antiviral potential
Cyanometabolites are active compounds derived from cyanobacteria that include small low molecular weight peptides, oligosaccharides, lectins,...
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Isolation, structural determination, and antiviral activities of a novel alanine-conjugated polyketide from Talaromyces sp.
Antiviral agents are highly sought after. In this study, a novel alkylated decalin-type polyketide, alaspelunin, was isolated from the culture broth...
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Bacteria exposed to antiviral drugs develop antibiotic cross-resistance and unique resistance profiles
Antiviral drugs are used globally as treatment and prophylaxis for long-term and acute viral infections. Even though antivirals also have been shown...
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Antiviral potential of essential oils and their plant sources, delivery methods, and drug development strategies with special focus on their mechanisms: a comprehensive review
The rise in viral infections has presented a multitude of public health concerns on a global scale, including the emergence of influenza and...
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Synthesis of new 3-acetyl-1,3,4-oxadiazolines combined with pyrimidines as antileishmanial and antiviral agents
A new series of 3-acetyl-1,3,4-oxadiazoline hybrid molecules was designed and synthesized using a condensation between acyclonucleosides and...
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Ivermectin antiviral activity against Varicellovirus bovinealpha 1: assessment of intracellular drug accumulation in virus-infected cells
Varicellovirus bovinealpha 1 (formerly b ovine alphaherpesvirus type 1 , BoAHV-1) is associated with several syndromes in cattle, including respiratory...
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Physicochemical and sequence determinants of antiviral peptides
Antiviral peptides (AVPs) open new possibilities as an effective antiviral therapeutic in the current scenario of evolving drug-resistant viruses....
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Insights into enterovirus a-71 antiviral development: from natural sources to synthetic nanoparticles
Enteroviruses are pathogens responsible for several diseases, being enterovirus A71 (EVA71) the second leading cause of hand, foot, and mouth disease...
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Antiviral Activity Against SARS-CoV-2 Variants Using in Silico and in Vitro Approaches
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emergence in 2019 led to global health crises and the persistent risk of viral...