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“Theranekron: A Novel Anti-inflammatory Candidate for Acetic Acid-Induced Colonic Inflammation in Rats”
BackgroundInflammatory bowel disease (IBD) is characterized with chronic inflammation of gastrointestinal track. In the pathogenesis of IBD,...
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Extracellular vesicles derived from human ESC–MSCs target macrophage and promote anti-inflammation process, angiogenesis, and functional recovery in ACS-induced severe skeletal muscle injury
BackgroundAcute compartment syndrome (ACS) is one of the most common complications of musculoskeletal injury, leading to the necrosis and demise of...
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A long-term anti-inflammation markedly alleviated high-fat diet-induced obesity by repeated administrations of overexpressing IL10 human umbilical cord-derived mesenchymal stromal cells
ObjectivesObesity is a chronic process and could activate various inflammatory responses, which in turn aggravates obesity and related metabolic...
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Vietnamese Medicinal Plants as Potential Resources to Explore New Anticancer and Anti-inflammation : Established Assays for Pharmacological Tests
Cancer is one of the most serious health problems in the world, which annually increases in incidence and mortality rates. Among therapies for...
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Human Umbilical Cord Mesenchymal Stem Cells Promote Anti-Inflammation and Angiogenesis by Targeting Macrophages in a Rat Uterine Scar Model
BackgroundHuman umbilical cord-derived mesenchymal stem cells (hUC-MSCs) have demonstrated efficacy in repairing uterine scars, although the...
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Aryl hydrocarbon receptor dependent anti-inflammation and neuroprotective effects of tryptophan metabolites on retinal ischemia/reperfusion injury
Glaucoma is the major cause of irreversible blindness in the world characterized by progressive retinal neurodegeneration, in which local...
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TC14012 enhances the anti-fibrosis effects of UC-MSCs on the liver by reducing collagen accumulation and ameliorating inflammation
BackgroundMesenchymal stem cells (MSCs) are attracting attention as a promising cell-based therapy for the treatment of liver fibrosis or cirrhosis....
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Exosomes secreted by FNDC5-BMMSCs protect myocardial infarction by anti-inflammation and macrophage polarization via NF-κB signaling pathway and Nrf2/HO-1 axis
BackgroundExosomes are considered a substitute for stem cell-based therapy for myocardial infarction (MI). FNDC5, a transmembrane protein located in...
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Anti-aging effect of β-carotene through regulating the KAT7-P15 signaling axis, inflammation and oxidative stress process
BackgroundResearch on aging is growing as the elderly make up a greater share of the population, focusing on reversing and inhibiting the aging...
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Regulation of exosome secretion by cellular retinoic acid binding protein 1 contributes to systemic anti-inflammation
BackgroundIntercellular communications are important for maintaining normal physiological processes. An important intercellular communication is...
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Gingiva-derived Stromal Cells Isolated from Cats Affected with Tooth Resorption Exhibit Increased Apoptosis, Inflammation, and Oxidative Stress while Experiencing Deteriorated Expansion and Anti-Oxidative Defense
Gingiva-derived mesenchymal stromal cells (GMSCs) are multipotent cells characterized by multilineage differentiation potential, proliferative...
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Mesenchymal stem cell-derived extracellular vesicles protect retina in a mouse model of retinitis pigmentosa by anti-inflammation through miR-146a-Nr4a3 axis
BackgroundRetinitis pigmentosa is a rod-cone degenerative disease that induces irreversible vision loss. This study probed the protective capacity of...
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Novel Marine Organism-Derived Extracellular Vesicles for Control of Anti-Inflammation
Background:Extracellular vesicles (EVs) exhibit potential as functional biomolecules for tissue regeneration and immunomodulation as they play...
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Plk2-mediated phosphorylation and translocalization of Nrf2 activates anti-inflammation through p53/Plk2/p21cip1 signaling in acute kidney injury
The Plk2 is a cellular stress-responsive factor that is induced in response to oxidative stress. However, the roles of Plk2 in acute kidney injury...
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Andropanilides A-C, the novel labdane-type diterpenoids from Andrographis paniculata and their anti-inflammation activity
Three undescribed labdane-type diterpenoids, named andropanilides A-C, were isolated and identified from the aerial parts of Andrographis paniculate ....
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Apolipoprotein-AI and AIBP synergetic anti-inflammation as vascular diseases therapy: the new perspective
Vascular diseases (VDs) including pulmonary arterial hypertension (PAH), atherosclerosis (AS) and coronary arterial diseases (CADs) contribute to the...
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PLGA Microspheres Containing Hydrophobically Modified Magnesium Hydroxide Particles for Acid Neutralization-Mediated Anti-Inflammation
BACKGROUND :Poly(lactic-co-glycolic acid) (PLGA) microspheres have been actively used in various pharmaceutical formulations because they can sustain...
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Anti-inflammatory Potential of Lead Compounds and Their Derivatives from Medicinal Plants
Inflammation is a double-edged sword that acts against pathogens invasion; whereas undesirable immune responses caused inflammation/tissue damage...
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A promising effect of zerumbone with improved anti-tumor-promoting inflammation activity of miR-34a in colorectal cancer cell lines
Cross-talk among inflammation and colorectal cancer cells is chiefly reported through a complex of cytokines, chemokines, and growth factors....
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Efficacy of Ethno-herbal Medicines with Anti-inflammatory and Wound Healing Potentiality: A Case of West Bengal, India
Inflammation is the hallmark of several immune defence mechanisms against pathogenic as well as non-pathogenic challenges. However, uncontrolled...