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An Integrated Method to Reconstruct Ancient Proteins
Proteins have played a fundamental role throughout life’s history on Earth. Despite their biological importance, ancient origin, early function, and...
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Analysis of Ancient Microbial DNA
The development of next-generation sequencing has led to a breakthrough in the analysis of ancient genomes, and the subsequent genomic analyses of...
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Ancient Wheat Genomes Illuminate Domestication, Dispersal, and Diversity
Ancient DNA (aDNA) promises to revolutionise our understanding of crop evolution. Wheat has been a major crop for millennia and has a particularly...
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Hot springs viruses at Yellowstone National Park have ancient origins and are adapted to thermophilic hosts
Geothermal springs house unicellular red algae in the class Cyanidiophyceae that dominate the microbial biomass at these sites. Little is known about...
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Seagrass genomes reveal ancient polyploidy and adaptations to the marine environment
We present chromosome-level genome assemblies from representative species of three independently evolved seagrass lineages: Posidonia oceanica , Cymodoc...
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Effects of microbial-converted ancient permafrost organic carbon on the growth and reproduction of Daphnia magna
Immense amounts of ancient (radiocarbon age over 200 years) organic carbon (OC) from permafrost are released into aquatic systems. Ancient...
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Preservation of proteins in the geosphere
Deep-time protein preservation has attracted increasing interest and rapid research activity within the palaeobiological community in recent years,...
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An ancient metalloenzyme evolves through metal preference modulation
Evolution creates functional diversity of proteins, the essential building blocks of all biological systems. However, studies of natural proteins...
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Genomics of Ancient Pathogens: First Advances and Prospects
AbstractPaleogenomics is one of the urgent and promising areas of interdisciplinary research in the today’s world science. New genomic methods of...
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Galectins: An Ancient Family of Carbohydrate Binding Proteins with Modern Functions
Galectins are a large family of carbohydrate binding proteins with members in nearly every lineage of multicellular life. Through tandem and en-mass...
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Foliar-Applied Zinc is Beneficial to Growth, Grain Yield, and Quality of Standard and Ancient Wheats Grown under Saline and Non-Saline Conditions
Ancient wheats are valuable genetic resources, though knowledge on their response to micronutrients in the presence of saline irrigation water is...
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The Ancient Origin and Function of Germline Cysts
Gamete production in most animal species is initiated within an evolutionarily ancient multicellular germline structure, the germline cyst, whose...
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Ancient dental calculus reveals oral microbiome shifts associated with lifestyle and disease in Great Britain
The prevalence of chronic, non-communicable diseases has risen sharply in recent decades, especially in industrialized countries. While several...
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Evolution of frustrated and stabilising contacts in reconstructed ancient proteins
Energetic properties of a protein are a major determinant of its evolutionary fitness. Using a reconstruction algorithm, dating the reconstructed...
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Chaperone proteins and peroxisomal protein import
Peroxisomes are ubiquitous organelles present in most eukaryotic cells. Their role in cellular metabolism is diverse among species. An array of genes...
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Evolution of CRISPR-associated endonucleases as inferred from resurrected proteins
Clustered regularly interspaced short palindromic repeats (CRISPR)-associated Cas9 is an effector protein that targets invading DNA and plays a major...
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Reconstruction of the last bacterial common ancestor from 183 pangenomes reveals a versatile ancient core genome
BackgroundCumulative sequencing efforts have yielded enough genomes to construct pangenomes for dozens of bacterial species and elucidate...
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Ancient Diatom DNA
An interesting feature of some diatom species is their ability to form resting stages, a dormant life stage that can allow them to survive long...
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Ancient homomorphy of molluscan sex chromosomes sustained by reversible sex-biased genes and sex determiner translocation
Contrary to classic theory prediction, sex-chromosome homomorphy is prevalent in the animal kingdom but it is unclear how ancient homomorphic sex...
