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An analytical workflow for dynamic characterization and quantification of metal-bearing nanomaterials in biological matrices
To assess the safety of engineered nanomaterials (ENMs) and to evaluate and improve ENMs’ targeting ability for medical application, it is necessary...
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A comprehensive workflow for optimizing RNA-seq data analysis
BackgroundCurrent RNA-seq analysis software for RNA-seq data tends to use similar parameters across different species without considering...
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An automated workflow for multi-omics screening of microbial model organisms
Multi-omics datasets are becoming of key importance to drive discovery in fundamental research as much as generating knowledge for applied...
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A new statistical workflow (R-packages based) to investigate associations between one variable of interest and the metabolome
IntroductionIn metabolomics, the investigation of associations between the metabolome and one trait of interest is a key research question. However,...
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aMeta: an accurate and memory-efficient ancient metagenomic profiling workflow
Analysis of microbial data from archaeological samples is a growing field with great potential for understanding ancient environments, lifestyles,...
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StarMap: a user-friendly workflow for Rosetta-driven molecular structure refinement
Cryogenic electron microscopy (cryo-EM) data represent density maps of macromolecular systems at atomic or near-atomic resolution. However, building...
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LiLA: lipid lung-based ATLAS built through a comprehensive workflow designed for an accurate lipid annotation
Accurate lipid annotation is crucial for understanding the role of lipids in health and disease and identifying therapeutic targets. However,...
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A single-sample workflow for joint metabolomic and proteomic analysis of clinical specimens
Understanding the interplay of the proteome and the metabolome helps to understand cellular regulation and response. To enable robust inferences from...
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An optimized workflow for MS-based quantitative proteomics of challenging clinical bronchoalveolar lavage fluid (BALF) samples
BackgroundClinical bronchoalveolar lavage fluid (BALF) samples are rich in biomolecules, including proteins, and useful for molecular studies of lung...
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A streamlined tandem tip-based workflow for sensitive nanoscale phosphoproteomics
Effective phosphoproteome of nanoscale sample analysis remains a daunting task, primarily due to significant sample loss associated with non-specific...
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UnCoVar: a reproducible and scalable workflow for transparent and robust virus variant calling and lineage assignment using SARS-CoV-2 as an example
BackgroundAt a global scale, the SARS-CoV-2 virus did not remain in its initial genotype for a long period of time, with the first global reports of...
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Workflow for shake flask and plate cultivations with fats for polyhydroxyalkanoate bioproduction
AbstractSince natural resources for the bioproduction of commodity chemicals are scarce, waste animal fats (WAF) are an interesting alternative...
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A two-step workflow based on plasma p-tau217 to screen for amyloid β positivity with further confirmatory testing only in uncertain cases
Cost-effective strategies for identifying amyloid-β (Aβ) positivity in patients with cognitive impairment are urgently needed with recent approvals...
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Systematic noise removal from analytical ultracentrifugation data with UltraScan
A method for removing time- and radially invariant noise from sedimentation velocity and sedimentation equilibrium experiments performed in an...
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Smart-Plexer: a breakthrough workflow for hybrid development of multiplex PCR assays
Develo** multiplex PCR assays requires extensive experimental testing, the number of which exponentially increases by the number of multiplexed...
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An MSstats workflow for detecting differentially abundant proteins in large-scale data-independent acquisition mass spectrometry experiments with FragPipe processing
Technological advances in mass spectrometry and proteomics have made it possible to perform larger-scale and more-complex experiments. The volume and...
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Systematic untargeted UHPLC–Q-TOF–MS based lipidomics workflow for improved detection and annotation of lipid sub-classes in serum
Introduction and objectiveTaking into consideration the challenges of lipid analytics, present study aims to design the best high-throughput workflow...
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Comprehensive multi-attribute method workflow for biotherapeutic characterization and current good manufacturing practices testing
The multi-attribute method (MAM) is a liquid chromatography-mass spectrometry (LC-MS)-based method that is used to directly characterize and monitor...
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Versatile and automated workflow for the analysis of oligodendroglial calcium signals
Although intracellular Ca 2+ signals of oligodendroglia, the myelin-forming cells of the central nervous system, regulate vital cellular processes...
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A glycomic workflow for LC–MS/MS analysis of urine glycosaminoglycan biomarkers in mucopolysaccharidoses
In recent years, several rational designed therapies have been developed for treatment of mucopolysaccharidoses (MPS), a group of inherited metabolic...
