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Cationic Amphiphilic Molecules as Bactericidal Agents
Cationic amphiphiles belong to the large as well as assorted category of antimicrobial agents, which has emerged as a sizzling topic of discussion...
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Effect of Fluoxetine on the Surface Behavior of the Lipid Monolayers at Different Surface Pressures
AbstractFluoxetine (FLX), used in the clinic to treat depression, is a well-known cationic amphiphilic antidepressant. However, there is a lack of...
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Amphiphilic peptide dendrimer-based nanovehicles for safe and effective siRNA delivery
Small interfering RNA (siRNA)-based RNA interference has emerged as a promising therapeutic strategy for the treatment of a wide range of incurable...
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Water Molecules Organization Surrounding Ions, Amphiphilic Protein Residues, and Hyaluronan
Water, that is so common in our environment and that is an essential component of our life, is an object of interest for researchers for centuries....
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The Structure of Oxysterols Determines Their Behavior at Phase Boundaries: Implications for Model Membranes and Structure–Activity Relationships
The presence of an additional polar group in the cholesterol backbone increases the hydrophilicity of resulting compounds (oxysterols), determines...
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Targeting Cancer Lysosomes with Good Old Cationic Amphiphilic Drugs
Being originally discovered as cellular recycling bins, lysosomes are today recognized as versatile signaling organelles that control a wide range of...
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Water Behavior Near the Lipid Bilayer
In this chapter, we focus on the dynamics of water molecules situated in the vicinity of a phospholipid bilayer. Using a molecular dynamics...
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Surface Activity and Emulsification Properties of Saponins as Biosurfactants
Saponins are group of chemical compounds found in many plants and some marine animals. Due to extensive biological activity, these compounds are...
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Characterization of dual nano-size effects of ACC-cellulose nanofibrils on crystallization behavior of hydrophilic poly(vinyl alcohol)
This study attempts to clarify thermodynamic quantification on interaction between poly(vinyl alcohol) (PVA) and wood-derived cellulose nanofibrils...
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Supramolecular assemblies from antimony(V) complexes for the treatment of leishmaniasis
The pentavalent meglumine antimoniate (MA) is still a first-line drug in the treatment of leishmaniasis in several countries. As an attempt to...
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Biosurfactants and Their Perspectives for Application in Drug Adsorption
The increase in the world population and the use of nonrenewable natural resources has made it necessary to find alternatives for more sustainable...
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CHIMs are versatile cholesterol analogs mimicking and visualizing cholesterol behavior in lipid bilayers and cells
Cholesterol is an essential component of cellular membranes regulating the structural integrity and fluidity of biological bilayers and cellular...
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Nanocarrier-mediated transdermal dsRNA-NPF1 delivery system contributes to pest control via inhibiting feeding behavior in Grapholita molesta
Grapholita molesta , a worldwide fruit-boring pest, is difficult to be effectively controlled due to the larvae feeding habit inside fruits....
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Conditions for Handling and Optimal Storage of Mycolactone
The successful isolation of mycolactone in a laboratory or from a clinical sample relies on proper handling and storage of the toxin. Mycolactone is...
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Palm kernel cake in high-concentrate diets for feedlot goat kids: nutrient intake, digestibility, feeding behavior, nitrogen balance, blood metabolites, and performance
This study was conducted to evaluate the effects of including palm kernel cake (PKC) in high-concentrate diets for feedlot goat kids on nutrient...
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The Functionality of Membrane-Inserting Proteins and Peptides: Curvature Sensing, Generation, and Pore Formation
Proteins and peptides with hydrophobic and amphiphilic segments are responsible for many biological functions. The sensing and generation of membrane...
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Characterization of mercerized cellulose nanofibrils prepared by aqueous counter collision process
Cellulose nanofibrils (CNFs) obtained by aqueous counter collision (ACC) methods have amphiphilic Janus-type properties, which appear markedly for...
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Nanocarriers for the Molecular Targeting of Pathogenic Bacteria
The rise of antibiotic-resistant pathogenic bacteria is a worldwide health problem that necessitates the creation of a novel treatment strategy. This...
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A ratiometric fluorescent nanoprobe for ultrafast imaging of peroxynitrite in living cells
For ratiometrically imaging peroxynitrite (ONOO − ) in living cells, we devised and fabricated a novel fluorescent nanoprobe, NC-NP 530/460 , in this...
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Alkali-activation of cellulose nanofibrils to facilitate surface chemical modification under aqueous conditions
In this study, we developed a surface-activation technique for cellulose nanofibrils (CNFs) using mild-alkali and aqueous conditions. CNFs were...
