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Clustered surface amino acid residues modulate the acid stability of GH10 xylanase in fungi
AbstractAcidic xylanases are widely used in industries such as biofuels, animal feeding, and fruit juice clarification due to their tolerance to...
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Amino acid intake strategies define pluripotent cell states
Mammalian preimplantation development is associated with marked metabolic robustness, and embryos can develop under a wide variety of nutrient...
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Broad Spectrum Amino Acid Racemases (Bsrs): A Potential Target in Microbial Research
Broad spectrum amino acid racemases (Bsrs) aid bacteria in producing non-canonical D-amino acids (NCDAA), which play significant functions in the...
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Monatin: (Super Sweet Amino Acid)
Intensive search on sweetness of natural amino acids started after attaining success in synthesising artificial health friendly super sweet aspartame...
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Introducing EzAAI: a pipeline for high throughput calculations of prokaryotic average amino acid identity
The average amino acid identity (AAI) is an index of pairwise genomic relatedness, and multiple studies have proposed its application in prokaryotic...
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Amino Acids Transport as an Index of Cancer Stem Cells Dysregulation
The appearance, proliferation, metastasis, and even resistance to chemotherapy depend on the molecular identity of the so-called Cancer Stem Cells...
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Novel recombinant aminoacylase from Paraburkholderia monticola capable of N-acyl-amino acid synthesis
AbstractN-Acyl-amino acids can act as mild biobased surfactants, which are used, e.g., in baby shampoos. However, their chemical synthesis needs acyl...
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Resource partitioning and amino acid assimilation in a terrestrial geothermal spring
High-temperature geothermal springs host simplified microbial communities; however, the activities of individual microorganisms and their roles in...
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Organizing the bacterial annotation space with amino acid sequence embeddings
BackgroundDue to the ever-expanding gap between the number of proteins being discovered and their functional characterization, protein function...
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Essential amino acid residues and catalytic mechanism of trans-epoxysuccinate hydrolase for production of meso-tartaric acid
ObjectivesThis study aimed to discuss the essential amino acid residues and catalytic mechanism of trans -epoxysuccinate hydrolase from Pseudomonas...
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Amino acid substitutions in specific proteins correlate with farnesol unresponsiveness in Candida albicans
BackgroundThe quorum-sensing molecule farnesol, in opportunistic yeast Candida albicans , modulates its dimorphic switch between yeast and hyphal...
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Amino acid analysis as a method of discovering biomarkers for diagnosis of diabetes and its complications
Diabetes mellitus (DM) is a severe chronic diseases with a global prevalence of 9%, leading to poor health and high health care costs, and is a...
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Metabuli: sensitive and specific metagenomic classification via joint analysis of amino acid and DNA
Metagenomic taxonomic classifiers analyze either DNA or amino acid (AA) sequences. Metabuli ( https://metabuli.steineggerlab.com ), however, jointly...
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Amino Acids Transport as an Index of Cancer Stem Cells Dysregulation
The appearance, proliferation, metastasis, and even resistance to chemotherapy depend on the molecular identity of the so-called Cancer Stem Cells...
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Chloroquine resistance evolution in Plasmodium falciparum is mediated by the putative amino acid transporter AAT1
Malaria parasites break down host haemoglobin into peptides and amino acids in the digestive vacuole for export to the parasite cytoplasm for growth:...
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Amino acid utilization allows intestinal dominance of Lactobacillus amylovorus
The mammalian intestine harbors heterogeneous distribution of microbes among which specific taxa (e.g. Lactobacillus ) dominate across mammals....
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Gamma Amino Butyric Acid (GABA) and Ferulic Acid Esterase (FAE) Producing Psychobiotic Bacteria Isolated from Cereal-Based Fermented Food
Gut microbiota plays an important role in regulating enteric, immune and neural pathways. Many neuropsychiatric disorders such as anxiety,...
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Bioorthogonal non-canonical amino acid tagging to track transplanted human induced pluripotent stem cell-specific proteome
BackgroundHuman induced pluripotent stem cells (hiPSCs) and their differentiated cell types have a great potential for tissue repair and...
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Structural insights into the amino acid usage variations in the profilin gene family
Profilin protein is present ubiquitously in all forms of life and is allied with allergic responses among atopic individuals. In addition to this,...
