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GCSscore: an R package for differential gene expression analysis in Affymetrix/Thermo-Fisher whole transcriptome microarrays
BackgroundDespite the increasing use of RNAseq for transcriptome analysis, microarrays remain a widely-used methodology for genomic studies. The...
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Application of Array-Based Oligonucleotides for Synthesis of Genetic Designs
AbstractThe application of array-based oligonucleotides in biological studies is described. These oligonucleotides are mainly used to design large...
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Genome-Wide Expression Analysis of Genes Involved in Somatic Embryogenesis
Genome-wide expression analysis is an important tool for identifying and analysing genes involved in various biological processes, including cell...
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Genetic Composition of the High-Quality Winter Wheat Varieties ‘**nmai 26’ and ‘**nmai 45’
High quality is an important goal of wheat breeding. Several superstrong gluten wheat varieties, e.g. ‘**nmai 26’ and ‘**nmai 45’, have been bred to...
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Prenatal diagnosis of 22q11.2 copy number abnormalities in fetuses via single nucleotide polymorphism array
The q11.2 region on chromosome 22 contains numerous low-copy repeats that lead to deleted or duplicated regions in the chromosome, thereby resulting...
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Microarray-Based Detection and Identification of Bacterial and Viral Plant Pathogens
The development and application of diagnostic procedures are influenced by a variety of circumstances. Plant viruses, unlike cellular diseases, have...
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Understanding of Root Nodule Development at Level of System Biology as Obtained by High Throughput Transcriptomic Approach
Nodule development starts with dedifferentiation of the already differentiated root tissues. Dedifferentiation involves a complex but finely tuned,...
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Integration of DNA Microarray with Clinical and Genomic Data
DNA microarrays have been widely employed to understand cancer development. This technology is able to measure expression levels of a large numbers...
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Cytogenetic identification and molecular marker development of a novel wheat–Thinopyrum ponticum translocation line with powdery mildew resistance
Key messageA new wheat– Thinopyrum ponticum translocation line with excellent powdery mildew resistance was produced, and alien-specific PCR markers...
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Simultaneous Isolation and Amplification of mRNA and Genomic DNA of a Single Cell
Many biological or pathological processes are driven by cells difficult to identify or isolate, i.e., rare cells. Very often, these cells have...
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Discovery and ranking of the most robust prognostic biomarkers in serous ovarian cancer
Progress in ovarian cancer treatment lags behind other tumor types. With diagnosis usually at an advanced stage, there is a high demand for reliable...
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Evolution in the Genoty** Platforms for Plant Breeding
Improving the crop productivity, resilience to climate extremes, resistance to biotic stress and improving the quality are the main breeding...
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Microarray Technology for Detection of Plant Diseases
DNA microarrays are a powerful technology that has great implications in plant sciences, biomedical sciences, veterinary, and pharmacological...
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Genetic Testing for Endometrial Receptivity
Endometrial receptivity is a gateway to a successful pregnancy. Emerging evidence has proven the crucial role of endometrial receptivity in...
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Single-Nucleotide Polymorphism
In forensic analysis, the conventional short tandem repeat (STR) markers are routinely used for examination of the biological samples. But, in the...
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Expression of human RECQL5 in Saccharomyces cerevisiae causes transcription defects and transcription-associated genome instability
RECQL5 is a member of the conserved RecQ family of DNA helicases involved in the maintenance of genome stability that is specifically found in higher...
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Multiomics Approach for Crop Improvement Under Climate Change
Crop enhancement and safety is prerequisite to accomplishing the requirement of develo** scenario such as population explosion, climate change, and...
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Carcinoma associated fibroblasts small extracellular vesicles with low miR-7641 promotes breast cancer stemness and glycolysis by HIF-1α
Fibroblasts play an important role in cancer development and progression. Small extracellular vesicles (sEVs) are one type of extracellular vesicles,...
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IMiDs uniquely synergize with TKIs to upregulate apoptosis of Philadelphia chromosome-positive acute lymphoblastic leukemia cells expressing a dominant-negative IKZF1 isoform
The long-term prognosis of Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph + ALL) is still unsatisfactory even after the emergence...
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Tools in Pharmacogenomics Biomarker Identification for Cancer Patients
The understanding of the biological differences which underlie the inter-individual variability in drug response improved the efficacy of cancer...