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Gemcitabine and APG-1252, a novel small molecule inhibitor of BCL-2/BCL-XL, display a synergistic antitumor effect in nasopharyngeal carcinoma through the JAK-2/STAT3/MCL-1 signaling pathway
Advanced nasopharyngeal carcinoma (NPC) has a poor prognosis, with an unfavorable response to palliative chemotherapy. Unfortunately, there are few...
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Iron reprogrammes the root system architecture by regulating OsWRKY71 in arsenic-stressed rice (Oryza sativa L.)
Iron (Fe) has been critically reported to act as a signal that can be interpreted to activate the molecular mechanisms involved in root developmental...
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Unraveling the complex evolutionary features of the Cinnamomum camphora mitochondrial genome
Key messageWe reported the mitochondrial genome of Cinnamomum camphora for the first time, revealing frequent rearrangement events in the non-coding...
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Cytogenetic Diversity in Scilloideae (Asparagaceae): a Comprehensive Recollection and Exploration of Karyo-Evolutionary Trends
The family Asparagaceae (subfamily Scilloideae, APG III, Botanical Journal of the Linnean Society 161:105–121,
2009 ) constitutes approximately 1000... -
Partially saturated canthaxanthin alleviates aging-associated oxidative stress in d-galactose administered male wistar rats
It has been earlier reported that partially saturated canthaxanthin (PSC) from Aspergillus carbonarius mutant is non-toxic, has anti-lipid...
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Family legacy: contrasting diversity–elevation relationships on a coastal Atlantic Forest mountain system
Unveiling the ecological processes driving diversity and its relationship to the environment remains a central goal in ecological studies. Here, we...
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Angiosperm Diversity in Nepal
This article provides a brief overview of Nepal’s existing knowledge of angiosperms. The diversity, distribution ranges, and exploration of...
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Spatial patterns of phylogenetic and species diversity of Fennoscandian vascular plants in protected areas
Protected areas are one of the main strategic means for conserving biodiversity. Yet, the design of protected areas usually neglects phylogenetic...
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Harnessing tissue-specific genome editing in plants through CRISPR/Cas system: current state and future prospects
Main conclusionIn a nutshell, tissue-specific CRISPR/Cas genome editing is the most promising approach for crop improvement which can bypass the...
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GC heterogeneity reveals sequence-structures evolution of angiosperm ITS2
BackgroundDespite GC variation constitutes a fundamental element of genome and species diversity, the precise mechanisms driving it remain unclear....
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Verbenaceae to Vochysiaceae
Information concerning typical features of families whose names starting with the letter ‘V’ is provided. Besides, important economic plants with...
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Holomorphology, Space, and Time to Shed Light on the Evolution and Distributional Pattern of the Endemic Flowering Plants of Brazil
The disparity in species richness among clades of angiosperms is partly explained by differences in evolutionary and biogeographic processes;...
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Contrasting patterns of phylogenetic diversity and alpine specialization across the alpine flora of the American mountain range system
Although mountainous habitats contribute substantially to global biodiversity, comparatively little is known about biogeographic patterns of...
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Characterization of a recombinant Aspergillus niger GZUF36 lipase immobilized by ionic liquid modification strategy
AbstractEnzyme immobilized on magnetic nanomaterials is a promising biocatalyst with efficient recovery under applied magnets. In this study, a...
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Improvement of leaf K+ retention is a shared mechanism behind CeO2 and Mn3O4 nanoparticles improved rapeseed salt tolerance
Salinity is a global issue limiting efficient agricultural production. Nanobiotechnology has been emerged as an effective approach to improve plant...
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BASAL LINEAGES
Cosmopolitan, in warm temperate and tropical regions, in rivers, ponds, lakes, and freshwater wetlands.
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An intermediate state allows influenza polymerase to switch smoothly between transcription and replication cycles
Influenza polymerase (FluPol) transcribes viral mRNA at the beginning of the viral life cycle and initiates genome replication after viral protein...
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Ultrastructure of influenza virus ribonucleoprotein complexes during viral RNA synthesis
The single-stranded, negative-sense, viral genomic RNA (vRNA) of influenza A virus is encapsidated by viral nucleoproteins (NPs) and an RNA...
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Roads as conduits of functional and phylogenetic degradation in Caatinga
Road networks cause degradation by mean of disturbances that can alter the biodiversity and the functioning of the Caatinga ecosystems. We tested the...
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Plastid phylogenomic insights into relationships of all flowering plant families
BackgroundFlowering plants (angiosperms) are dominant components of global terrestrial ecosystems, but phylogenetic relationships at the familial...
