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Identification of Potential Peptide Inhibitors of ACE-2 Target of SARS-CoV-2 from Buckwheat & Quinoa
It is well established fact that peptides from various foods offer human health benefits displaying diverse functionalities. Millets considered as...
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Phenoty** of M1 and M2a Macrophages and Differential Expression of ACE-2 on Monocytes by Flow Cytometry: Impact of Cell Culture Conditions and Sample Processing
Macrophages are ubiquitously distributed throughout the various tissues of the body and perform many functions including the orchestration of...
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Association of ACE I/D gene polymorphism and related risk factors in impaired fasting glucose and type 2 diabetes: a study among two tribal populations of North-East India
BackgroundType 2 diabetes is a serious public health concern in India, even the indigenous tribal populations are not left unaffected. The present...
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Identification of novel inhibitors of angiotensin-converting enzyme 2 (ACE-2) receptor from Urtica dioica to combat coronavirus disease 2019 (COVID-19)
AbstractThe pandemic outbreak of coronavirus (SARS-CoV-2) is rapidly spreading across the globe, so the development of anti-SARS-CoV-2 agents is...
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The Effect of Different Carbon Sources on Nitrate-Dependent Iron Oxidation Process, Bacterial Diversity, and C Protagonist in Varied Texture Soils
Nitrate-dependent Fe-oxidizing bacteria (NFeOB) are key mediators for carbon (C) and nitrogen (N) cycling in paddy soils. The aim of this study was...
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ACE I/D polymorphism is a risk factor for the clinical severity of COVID-19 in Brazilian male patients
BackgroundThe renin-angiotensin system is potentially involved in the pathogen-host interaction in the disease caused by SARS-CoV-2, since the...
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In Vitro Structure–Activity Relationship Study of a Novel Octapeptide Angiotensin-I Converting Enzyme (ACE) Inhibitor from the Freshwater Mussel Lamellidens marginalis
Angiotensin-I Converting Enzyme (ACE) plays a pivotal role in regulating hypertension. Inhibition of ACE by potent inhibitors is an excellent...
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Effects of Agarum clathratum extract on cell death and calcium ion levels of ovarian cancer cell
BackgroundIn recent years, marine algae are receiving attention due to their health benefits such as anti-oxidative, anti-bacterial,...
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Utilization of Marine Seaweeds as a Promising Defense Against COVID-19: a Mini-review
COVID-19 is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which mainly affects the respiratory system....
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Comparison of Amino Acid Profile, ACE Inhibitory Activity, and Organic Acid Profile of Cow and Goat Yogurts Produced with Lactobacillus acidophilus LA-5, Bifidobacterium animalis subsp. lactis BB-12, and Classical Yogurt Culture
In this study, we aimed to produce a standard, more functional, and nutritious yogurt by using 5 different combinations of cow milk and goat milk and...
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Association investigations between ACE1 and ACE2 polymorphisms and severity of COVID-19 disease
Due to the unique affinity of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to the angiotensin-converting enzyme 2 (ACE2) receptor...
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Simulation of COVID-19 symptoms in a genetically engineered mouse model: implications for the long haulers
The ongoing pandemic (also known as coronavirus disease-19; COVID-19) by a constantly emerging viral agent commonly referred as the severe acute...
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The ‘Insertion/Deletion’ Polymorphism, rs4340 and Diabetes Risk: A Pilot Study from a Hospital Cohort
The insertion/deletion, I/D polymorphism, in the gene encoding Angiotensin Converting Enzyme, ACE is a popular genetic marker for cardiovascular...
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Phenolic bioactive-linked antioxidant, anti-hyperglycemic, and antihypertensive properties of sweet potato cultivars with different flesh color
Sweet potato is a rich source of antioxidant phytohemicals, like β-carotene, vitamin C, anthocyanins, xanthophylls, and phenolics, which are relevant...
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Genetic polymorphisms of pharmacogenomic VIP variants in the Hui population from Ningxia Province of China
Pharmacogenomics has been widely used to study the very important pharmacogenetic (VIP) variants among different populations. However, there is...
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An insight into the mechanisms of COVID-19, SARS-CoV2 infection severity concerning β-cell survival and cardiovascular conditions in diabetic patients
A significantly high percentage of hospitalized COVID-19 patients with diabetes mellitus (DM) had severe conditions and were admitted to ICU. In this...
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Plant-Derived Natural Compounds as an Emerging Antiviral in Combating COVID-19
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a human virus that burst at Wuhan in China and spread quickly over the world, leading...
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Aerobic physical training reduces severe asthma phenotype involving kinins pathway
IntroductionAerobic physical training (APT) reduces eosinophilic airway inflammation, but its effects and mechanisms in severe asthma remain unknown.
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Plant-Derived Immunomodulators Targeting COVID-19 (SARS-CoV-2): Preclinical Evaluation and Clinical Trials
Coronavirus disease-2019 (COVID-19) is a contagious disease that originated and proliferated via a novel viral strain named Severe Acute Respiratory...
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The Link Between Heat Shock Proteins, Renin-Angiotensin System, and the Coagulation Cascade in the Pathogenesis of the Coronavirus-19 Disease
Introduction: Understanding the pathogenesis of COVID-19 is integral for its successful treatment. Methods: Available literature on the relationship...