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MiR-146a-5p, targeting ErbB4, promotes 3T3-L1 preadipocyte differentiation through the ERK1/2/PPAR-γ signaling pathway
BackgroundMicroRNAs (MiRNAs) are known to participate in preadipocyte differentiation, but the manner in which miR-146a-5p participates in this...
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Heme oxygenase-1 mediates the inhibitory effect of ginseng (Panax ginseng) leaf extract on differentiation in 3T3-L1 adipocytes
BackgroundObesity, which is defined as the excess accumulation of body fat, poses metabolic diseases that result in significant health risks. Since...
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Gut bacteria-derived 3-phenylpropionylglycine mitigates adipocyte differentiation of 3T3-L1 cells by inhibiting adiponectin-PPAR pathway
BackgroundGut microbiota provide numerous types of metabolites that humans cannot produce and have a huge influence on the host metabolism....
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Knockdown of ANGPTL4 inhibits adipogenesis of preadipocyte via autophagy
It has been demonstrated that angiopoietin-like protein 4 (ANGPTL4) plays an important regulatory role in lipid metabolism and backfat deposition...
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Inhibition of palmitic acid induced adipogenesis by natural polyphenols in 3T3-L1 adipocytes
AbstractDietary free fatty acids induce preadipocyte differentiation in the presence of a hormonal cocktail in 3T3-L1 adipocytes. Plant polyphenols...
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Hypocholesterolemic potential of Bacillus amyloliquefaciens KAVK1 modulates lipid accumulation on 3T3-L1 adipose cells and high fat diet-induced obese rat model
The significance of microorganisms occurring in foods is predominantly targeted due to their application for identifying a novel range of the...
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Plant miR167e-5p promotes 3T3-L1 adipocyte adipogenesis by targeting β-catenin
Adipogenesis is important in the development of fat deposition. Evidence showed that plant microRNAs (miRNAs) could be absorbed by the digestive...
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CircSSBP2 acts as a MiR-2400 sponge to promote intramuscular preadipocyte proliferation by regulating NDRG1
Intramuscular fat (IMF) is a critical factor in beef quality. IMF is mainly distributed between muscle fibres and its accumulation can affect the...
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Effect of Abutilon indicum (L) Extract on Adipogenesis, Lipolysis and Cholesterol Esterase in 3T3-L1 Adipocyte Cell Lines
Abutilon indicum (L) is an Indian traditional plant used for the treatment of diabetes and heart diseases. The present study is to evaluate the...
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Frequency-specific sensitivity of 3T3-L1 preadipocytes to low-intensity vibratory stimulus during adipogenesis
Adipocyte accumulation in the bone marrow is a severe complication leading to bone defects and reduced regenerative capacity. Application of external...
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α-Poly-l-lysine functions as an adipogenic inducer in 3T3-L1 preadipocytes
α-Poly -l- lysine (PLL) has been used for various purposes such as cell attachment, immunization, and molecular delivery, and is known to be cytotoxic...
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3,5-Dimethoxy-4-benzoic acid (syringic acid) a natural phenolic acid reduces reactive oxygen species in differentiated 3T3-L1 adipocytes
Preadipocytes under nutrient excess mature to lipid-laden adipocytes that are hotspots for generation of reactive oxygen species (ROS) imbalance and...
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Molecular mechanism of down-regulating adipogenic transcription factors in 3T3-L1 adipocyte cells by bioactive anti-adipogenic compounds
Obesity is growing at an alarming rate, which is characterized by increased adipose tissue. It increases the probability of many health...
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Low expression of ELOVL6 may be involved in fat loss in white adipose tissue of cancer-associated cachexia
BackgroundCancer-associated cachexia (CAC) arises from malignant tumors and leads to a debilitating wasting syndrome. In the pathophysiology of CAC,...
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m6A demethylase FTO regulate CTNNB1 to promote adipogenesis of chicken preadipocyte
BackgroundN6-methyladenosine (m 6 A) is an abundant post-transcriptional RNA modification that affects various biological processes. The fat mass and...
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Anti‐adipogenic Effects of αAL14 Mediated by Modulation of PI3K/Akt Pathways in 3T3-L1 Cells
AbstractA model peptide, αAL14, was designed from the primary structure of a novel antimicrobial peptide purified form the abalone. αAL14 was only...
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Beta-catenin inhibits TR4-mediated lipid accumulation in 3T3-L1 adipocytes via induction of Slug
BackgroundTR4, an orphan nuclear receptor plays a key role in glucose and lipid metabolism by regulating the expression of genes involved in energy...
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Melatonin Induces Apoptotic Cell Death in 3T3-L1 Preadipocytes
AbstractObesity is a major disease that causes significant complications. Inhibition of preadipocyte proliferation has the potential to prevent...
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An immortal porcine preadipocyte cell strain for efficient production of cell-cultured fat
Adding adipose cells to cell-cultured meat can provide a distinctive aroma and juicy texture similar to real meat. However, a significant challenge...
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Transcriptional analyses of the effects of Catharanthus roseus L. medicinal plant extracts on some markers related to obesity and inflammation in 3T3-L1 mouse cell lines
Catharanthus roseus L. ( C. roseus ) is one of the medicinal plants used to treat diabetes. In this study, 3T3-L1 preadipocyte cell lines which are...
