Search
Search Results
-
Effects of mifepristone on adipocyte differentiation in mouse 3T3-L1 cells
BackgroundBoth glucocorticoid receptor and peroxisome proliferator-activated receptor-γ (PPARγ) play a critical role in adipocyte differentiation....
-
Quercetin declines LPS induced inflammation and augments adiponectin expression in 3T3-L1 differentiated adipocytes SIRT-1 dependently
BackgroundInflammation is an important factor contributing to obesity-induced metabolic disorders. Different investigations confirm that local...
-
Heme oxygenase-1 mediates the inhibitory effect of ginseng (Panax ginseng) leaf extract on differentiation in 3T3-L1 adipocytes
BackgroundObesity, which is defined as the excess accumulation of body fat, poses metabolic diseases that result in significant health risks. Since...
-
MiR-146a-5p, targeting ErbB4, promotes 3T3-L1 preadipocyte differentiation through the ERK1/2/PPAR-γ signaling pathway
BackgroundMicroRNAs (MiRNAs) are known to participate in preadipocyte differentiation, but the manner in which miR-146a-5p participates in this...
-
Gut bacteria-derived 3-phenylpropionylglycine mitigates adipocyte differentiation of 3T3-L1 cells by inhibiting adiponectin-PPAR pathway
BackgroundGut microbiota provide numerous types of metabolites that humans cannot produce and have a huge influence on the host metabolism....
-
Hypocholesterolemic potential of Bacillus amyloliquefaciens KAVK1 modulates lipid accumulation on 3T3-L1 adipose cells and high fat diet-induced obese rat model
The significance of microorganisms occurring in foods is predominantly targeted due to their application for identifying a novel range of the...
-
Inhibition of palmitic acid induced adipogenesis by natural polyphenols in 3T3-L1 adipocytes
AbstractDietary free fatty acids induce preadipocyte differentiation in the presence of a hormonal cocktail in 3T3-L1 adipocytes. Plant polyphenols...
-
7-MEGA™ inhibits adipogenesis in 3T3-L1 adipocytes and suppresses obesity in high-fat-diet-induced obese C57BL/6 mice
BackgroundOverweight, often known as obesity, is the abnormal and excessive accumulation of fat that exposes the health of a person at risk by...
-
Plant miR167e-5p promotes 3T3-L1 adipocyte adipogenesis by targeting β-catenin
Adipogenesis is important in the development of fat deposition. Evidence showed that plant microRNAs (miRNAs) could be absorbed by the digestive...
-
RETRACTED ARTICLE: MiRNA-27a mediates insulin resistance in 3T3-L1 cells through the PPARγ
The biological actions of insulin have been originated by activation of membrane receptors, which trigger a diversity of signaling pathways in...
-
BGM, a Newly Synthesised Boron Compound, Induces Apoptosis and Reduces Oxidative Stress by Inhibiting Lipogenesis in 3T3-L1 Adipocytes via PPARγ and CTRP3
Obesity is a chronic disease associated with increased morbidity and mortality. The rapidly increasing prevalence of obesity makes it a global health...
-
Effect of Abutilon indicum (L) Extract on Adipogenesis, Lipolysis and Cholesterol Esterase in 3T3-L1 Adipocyte Cell Lines
Abutilon indicum (L) is an Indian traditional plant used for the treatment of diabetes and heart diseases. The present study is to evaluate the...
-
The effects of glipizide on DNA damage and nuclear transport in differentiated 3T3-L1 adipocytes
BackgroundDespite commonly use for treatment of type II diabetes, possible effects of glipizide on nuclear transport and DNA damage in cells are...
-
Glucose enhances catecholamine-stimulated lipolysis via increased glycerol-3-phosphate synthesis in 3T3-L1 adipocytes and rat adipose tissue
BackgroundDuring lipolysis, triglyceride (TG) are hydrolyzed into a glycerol and fatty acids in adipocyte. A significant portion of the fatty acids...
-
α-Poly-l-lysine functions as an adipogenic inducer in 3T3-L1 preadipocytes
α-Poly -l- lysine (PLL) has been used for various purposes such as cell attachment, immunization, and molecular delivery, and is known to be cytotoxic...
-
Frequency-specific sensitivity of 3T3-L1 preadipocytes to low-intensity vibratory stimulus during adipogenesis
Adipocyte accumulation in the bone marrow is a severe complication leading to bone defects and reduced regenerative capacity. Application of external...
-
3,5-Dimethoxy-4-benzoic acid (syringic acid) a natural phenolic acid reduces reactive oxygen species in differentiated 3T3-L1 adipocytes
Preadipocytes under nutrient excess mature to lipid-laden adipocytes that are hotspots for generation of reactive oxygen species (ROS) imbalance and...
-
Molecular mechanism of down-regulating adipogenic transcription factors in 3T3-L1 adipocyte cells by bioactive anti-adipogenic compounds
Obesity is growing at an alarming rate, which is characterized by increased adipose tissue. It increases the probability of many health...
-
Anti‐adipogenic Effects of αAL14 Mediated by Modulation of PI3K/Akt Pathways in 3T3-L1 Cells
AbstractA model peptide, αAL14, was designed from the primary structure of a novel antimicrobial peptide purified form the abalone. αAL14 was only...
-
Beta-catenin inhibits TR4-mediated lipid accumulation in 3T3-L1 adipocytes via induction of Slug
BackgroundTR4, an orphan nuclear receptor plays a key role in glucose and lipid metabolism by regulating the expression of genes involved in energy...
