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A guide to barley mutants
BackgroundMutants have had a fundamental impact upon scientific and applied genetics. They have paved the way for the molecular and genomic era, and...
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Strategies for Screening Induced Mutants for Stress Tolerance
Crop plants are exposed to a multitude of biotic and abiotic factors, which necessitates improving tolerance/resistance in plant germplasm using...
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Conformational Transitions in EGFR Protein Tyrosine Kinase Domain and Their Modulation by Mutants
The epidermal growth factor receptor (EGFR) is a membrane protein with intracellular kinase activity. The EGFR plays a significant role in the cell...
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Role of Silicon in Mediating Salt Stress Responses in Arabidopsis Methylation Mutants
PurposeThe growing prevalence of soil salinity presents a significant threat to agriculture production on a global scale. Previous studies on salt...
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C-terminal frameshift mutations generate viable knockout mutants with developmental defects for three essential protein kinases
Loss-of-function mutants are fundamental resources for gene function studies. However, it is difficult to generate viable and heritable knockout...
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Zebrafish nampt-a mutants are viable despite perturbed primitive hematopoiesis
BackgroundNicotinamide phosphoribosyltransferase (Nampt) is required for recycling NAD + in numerous cellular contexts. Morpholino-based knockdown of...
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Alternate Bearing Tendency in Gamma-Ray Induced Mutants of ‘Amasya’ Apple
The ‘Amasya’, the primary cultivar of Turkey, was irradiated in 2011 with 29.01-Gy gamma rays determined the optimal mutagen dosage using a 60 Co...
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Characterization of Mutants and Cause of Flower Color Mutations
A large number of mutant varieties have been reported in different ornamental plants, but reports on a comparative evaluation of original and mutant...
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Generation of selenium-rich wheat mutants and exploration of responsive genes for selenium accumulation
Key messageSalt tolerance, selenium accumulation and expression of the responsive genes were analyzed in the wheat high selenium mutants.
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Development and characterization of Chlamydomonas reinhardtii low chlorophyll mutants to improve photosynthetic efficiency and biomass
The ability of the microalgae to utilize light efficiently is the critical factor for growth and biomass productivity through photosynthesis. Here,...
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Application of Flow Cytometry for Viability Assay of Mutants for Translation Termination Factors in the Yeast Saccharomyces cerevisiae
AbstractNonsense mutations in the essential SUP45 and SUP35 genes encoding translation termination factors affect the viability of Saccharomyces...
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Detection of genetic divergence among putative ethyl methane sulfonate mutants of super basmati using microsatellite markers
BackgroundSeeds of super basmati were mutagenized with different ethyl methane sulphonate (EMS) doses for creating genetic variability.
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Efficiency of Escherichia coli and Bacillus subtilis Expression Systems for Production of Binase Mutants
AbstractBacillus pumilus ribonuclease (binase) exhibits cytotoxic and oncolytic properties, while causing genotoxic effects at high concentrations....
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Structure and biological activity in vitro of Flagellin and its mutants from Escherichia coli Nissle 1917
Bacterial flagellin is a potent immunomodulatory agent. Previously, we successfully obtained flagellin from Escherichia coli Nissle 1917 (FliC EcN )...
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Generation and characterization of reduced PSII antenna size mutants of Chlorella sorokiniana for improved biomass
Biofuel production from algal biomass is a fundamental component in develo** sustainable energy sources that can replace fossil fuels. However,...
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Survey of prothioconazole sensitivity in Fusarium pseudograminearum isolates from Henan Province, China, and characterization of resistant laboratory mutants
BackgroundFusarium crown rot (FCR) is one of the most significant diseases limiting crop production in the Huanghuai wheat-growing region of China....
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Evaluation of altered starch mutants and identification of candidate genes responsible for starch variation in wheat
BackgroundInduction of mutation through chemical mutagenesis is a novel approach for preparing diverse germplasm. Introduction of functional alleles...
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Physiological, transcriptome and co-expression network analysis of chlorophyll-deficient mutants in flue-cured tobacco
BackgroundPhotosynthetic pigments in higher plants, including chlorophyll (Chl) and carotenoids, are crucial for photosynthesis and photoprotection....
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High-throughput creation of Nicotiana tabacum gene-targeted mutants based on CRISPR/Cas9
Key message4382 available sgRNAs targeting 1060 tobacco genes were obtained, and 10,682 targeted mutants were created using high-throughput methods....
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Excited-state observation of active K-Ras reveals differential structural dynamics of wild-type versus oncogenic G12D and G12C mutants
Despite the prominent role of the K-Ras protein in many different types of human cancer, major gaps in atomic-level information severely limit our...
