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Screening and identification of phytochemical drug molecules against mutant BRCA1 receptor of breast cancer using computational approaches
The American Cancer Society claims that breast cancer is the second most significant cause of cancer-related death, with over one million women...
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Research on seismic performance of traditional Chinese hall-style timber buildings in the Song and Yuan dynasties (960–1368 AD): a case study of the main hall of Baoguo Temple
The hall-style timber frame built in the Song and Yuan dynasties (960–1368 AD) is one of the most important structural prototypes of the traditional...
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Detection of genetic variation and base modifications at base-pair resolution on both DNA and RNA
Accurate decoding of nucleic acid variation is critical to understand the complexity and regulation of genome function. Here we use a single-molecule...
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Self-Assembly and Fabrication of Biomaterials onto Transducers and Their Characterization
Biosensor applies the immobilized biomaterials as the sensitive components, and the performances of the biosensor are greatly defined by the activity... -
Exploring viral diversity and metagenomics in livestock: insights into disease emergence and spillover risks in cattle
Cattle have a significant impact on human societies in terms of both economics and health. Viral infections pose a relevant problem as they directly...
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Spatial map** of cellular senescence: emerging challenges and opportunities
Cellular senescence is a well-established driver of aging and age-related diseases. There are many challenges to map** senescent cells in tissues...
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Current Insights into the Potential of Gene Therapy to Treat Rare Mitochondrial Diseases
Mitochondrial disorders represent a rare category of diseases that arise from abnormalities in essential proteins necessary for the proper... -
Isolation and sequencing of a single copy of an introgressed chromosome from a complex genome for gene and SNP identification
Key messageThis manuscript describes the identification, isolation and sequencing of a single chromosome containing high value resistance genes from...
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A global evaluation of mitochondrial DNA diversity and distribution of dromedary, Camelus dromedarius from north-central Saudi Arabia
Knowledge of genetic variability within and among types and breeds of dromedary ( Camelus dromedarius L.) can be a valuable asset in selective...
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Do highways influence the genetic structure of coyotes (Canis latrans) in a highly fragmented urban–rural landscape in central Mexico?
Central Mexico has suffered accelerated rates of habitat fragmentation caused by the growth of agriculture, industry, and rural and urban settlements...
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Diseases of Cassava
Cassava (Manihot esculenta Crantz) has become a staple crop in sub-Saharan African (SSA) regions of the globe. The crop possesses unquantifiable... -
Identification of potential rice lines harboring phosphorus uptake 1 QTL using diagnostic markers
Soil phosphorus (P) deficiency is a major constraint on rice productivity. Identifying donors with better uptake and yield under low soil P is...
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Modern Tools for Detection and Diagnosis of Plant Pathogens
Plant diseases contribute to an estimated annual crop loss of $60 billion worldwide, threatening the food security and thereby the survival of... -
Virus–Vector Interactions and Transmission
Plant viruses cause significant economic losses in agriculture by affecting crop yield and quality. The transmission of these viruses often relies on... -
Plasma cortisol and production of miRNAs in red drum (Sciaenops ocellatus) exposed to three distinct challenges
The red drum Sciaenops ocellatus is a marine fish species of high commercial interest. Despite improvements in current aquaculture practices, there...
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Human thirst behavior requires transformation of sensory inputs by intrinsic brain networks
BackgroundTo survive and thrive, many animals, including humans, have evolved goal-directed behaviors that can respond to specific physiological...
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Systems Biology and Hospital-Associated Infections
Hospital-associated infections (HAIs) have become a major threat and lead to almost over 90,000 deaths globally per year. Advanced methods of... -
DNA from non-viable bacteria biases diversity estimates in the corals Acropora loripes and Pocillopora acuta
BackgroundNucleic acid-based analytical methods have greatly expanded our understanding of global prokaryotic diversity, yet standard metabarcoding...
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