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Integrative analysis reveals associations between oral microbiota dysbiosis and host genetic and epigenetic aberrations in oral cavity squamous cell carcinoma
Dysbiosis of the human oral microbiota has been reported to be associated with oral cavity squamous cell carcinoma (OSCC) while the host-microbiota...
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The diversity, distribution, and temporal stability of coral ‘zooxanthellae’ on a pacific reef: from the scale of individual colonies to across the host community
The ecological and evolutionary consequences of partner fidelity and flexibility among coral–dinoflagellate mutualisms are widely debated. Resident...
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Molecular Basis of Host–Pathogen Interaction: An Overview
The concept of plant–pathogen interaction involves individual pathways for effective defense and successful colonization. The early detection of... -
Identification, Detection, and Management of Geminiviruses as Biotic Stress of Vegetable Crops
Vegetables are the largest horticultural product, contributing not only to nutritional diversity but also to farmer’s individual and national... -
Pattern-Triggered Immunity and Effector-Triggered Immunity: crosstalk and cooperation of PRR and NLR-mediated plant defense pathways during host–pathogen interactions
The elucidation of the molecular basis underlying plant-pathogen interactions is imperative for the development of sustainable resistance strategies...
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Lemur Gut Microeukaryotic Community Variation Is Not Associated with Host Phylogeny, Diet, or Habitat
Identifying the major forces driving variation in gut microbiomes enhances our understanding of how and why symbioses between hosts and microbes...
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Next-Gen Dual Transcriptomics for Adult Extrapulmonary Tuberculosis Biomarkers and Host–Pathogen Interplay in Human Cells: A Strategic Review
Tuberculosis (TB) is a major public health concern that results in significant morbidity and mortality, particularly in middle- to low-income...
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The Potential of Systems Biology to Understand the Tenets of Host-pathogen Interaction, Toxicology, and Aging
This chapter highlights the potential of systems biology in elucidating the fundamental principles underlying host-pathogen interaction, toxicology,... -
The eINTACT method for studying nuclear changes in host plant cells targeted by bacterial effectors in native infection contexts
Type-III effector proteins are major virulence determinants that most gram-negative bacteria inject into host cells to manipulate cellular processes...
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Pathogen detection in RNA-seq data with Pathonoia
BackgroundBacterial and viral infections may cause or exacerbate various human diseases and to detect microbes in tissue, one method of choice is RNA...
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Adaptation to host cell environment during experimental evolution of Zika virus
Zika virus (ZIKV) infection can cause important developmental and neurological defects in Humans. Type I/III interferon responses control ZIKV...
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Cut site preference allows influenza A virus PA-X to discriminate between host and viral mRNAs
Many viruses block host gene expression to take over the infected cell. This process, termed host shutoff, is thought to promote viral replication by...
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Antibiotics-induced dysbiosis in gut microbiota affects bumblebee health via regulating host amino acid metabolism
The gut bacteria can provide nutrition for the host, and regulate host physiological functions and host behavior. In this study, we specifically...
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Effects of Host Plants on Development and Immunity of a Generalist Insect Herbivore
Secondary plant chemistry mediates a variety of communication signals among species, playing a fundamental role in the evolutionary diversification...
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Human papillomaviruses: diversity, infection and host interactions
Human papillomaviruses (HPVs) are an ancient and highly successful group of viruses that have co-evolved with their host to replicate in specific...
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Transmission of parasitic mites (Riccardoella oudemansi) between limacid slug hosts: the role of parasite and host behaviour
Transmission between hosts is crucial to the growth, development and reproduction of many parasites. As a consequence, parasites are under selection...
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Host factor TNK2 is required for influenza virus infection
BackgroundHost factors are required for Influenza virus infection and have great potential to become antiviral target.
ObjectiveHere we demonstrate...
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Genome-wide association reveals host-specific genomic traits in Escherichia coli
BackgroundEscherichia coli is an opportunistic pathogen which colonizes various host species. However, to what extent genetic lineages of E. coli ...
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A single laccase acts as a key component of environmental sensing in a broad host range fungal pathogen
Secreted laccases are important enzymes on a broad ecological scale for their role in mediating plant-microbe interactions, but within ascomycete...