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Homology Modeling of Antibody Variable Regions: Methods and Applications
Adaptive immunity specifically protects us from antigenic challenges. Antibodies are key effector proteins of adaptive immunity, and they are...
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Pseudogenes act as a neutral reference for detecting selection in prokaryotic pangenomes
A long-standing question is to what degree genetic drift and selection drive the divergence in rare accessory gene content between closely related...
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Micro-habitat features determine oviposition site selection in High Brown and Dark Green Fritillaries
AbstractThe survival of butterfly populations depends on successful oviposition strategies. The limited mobility of early life stages requires...
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Pre-selection against a lethal recessive allele in breeding schemes with optimum-contribution selection or truncation selection
BackgroundWe tested the hypothesis that breeding schemes with a pre-selection step, in which carriers of a lethal recessive allele (LRA) were culled,...
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Analysis of historical selection in winter wheat
Key MessageModeling of the distribution of allele frequency over year of variety release identifies major loci involved in historical breeding of...
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New statistical selection method for pleiotropic variants associated with both quantitative and qualitative traits
BackgroundIdentification of pleiotropic variants associated with multiple phenotypic traits has received increasing attention in genetic association...
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Reproductive patterns, morpho-agronomic variability and selection for breeding Hancornia speciosa Gomes (Apocynaceae)
Hancornia speciosa is a fruit tree species with the potential for exploitation, which makes the adoption of strategies related to its conservation...
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Salinity-triggered homogeneous selection constrains the microbial function and stability in lakes
AbstractClimate change and anthropogenic exploitation have led to the gradual salinization of inland waters worldwide. However, the impacts of this...
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Phenomic Selection: A New and Efficient Alternative to Genomic Selection
Recently, it has been proposed to switch molecular markers to near-infrared (NIR) spectra for inferring relationships between individuals and further...
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Common lizard microhabitat selection varies by sex, parity mode, and colouration
BackgroundAnimals select and interact with their environment in various ways, including to ensure their physiology is at its optimal capacity, access...
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Antibody selection strategies and their impact in predicting clinical malaria based on multi-sera data
BackgroundNowadays, the chance of discovering the best antibody candidates for predicting clinical malaria has notably increased due to the...
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Playing with plant height and spike number in Brazilian wheat: an applied study on early-generation selection effects
Although genomic tools have proven to be very useful for plant breeding, most bread wheat breeding programs at develo** countries still rely solely...
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Pan-genome of Citrullus genus highlights the extent of presence/absence variation during domestication and selection
The rich genetic diversity in Citrullus lanatus and the other six species in the Citrullus genus provides important sources in watermelon breeding....
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Behavioral habitat selection of wood bison (Bison bison athabascae) in boreal forests
Habitat selection is critical to informing wildlife management and conservation. However, different behaviors require the use of different habitat...
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Winter food selection and exploratory behavior vary with natal territory characteristics in wild great tits
AbstractDifferences in habitat characteristics experienced during rearing associate with variation in a range of behavioral phenotypes such as...
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Ensemble feature selection with data-driven thresholding for Alzheimer's disease biomarker discovery
BackgroundFeature selection is often used to identify the important features in a dataset but can produce unstable results when applied to...
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Unravelling urban nesting site selection in an opportunistic gull: an integrated analysis of micro-spatial habitat and litter quantification
The proliferation of gull populations in urban areas has led to an increase in human-gull conflicts, especially in highly populated cities where...
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Does predation drive Chilean Elaenia (Elaenia chilensis) nest-site selection in the temperate forest of southern South America?
Nest-site selection is a behavioral response that can provide protection for adults, eggs and nestlings, affecting fitness. Since predation is the...
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Integrating ecological niche modeling and rates of evolution to model geographic regions of mimetic color pattern selection
Geographic variation in natural selection derived from biotic sources is an important driver of trait evolution. The evolution of Müllerian mimicry...
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Disparities in spatially variable gene calling highlight the need for benchmarking spatial transcriptomics methods
Identifying spatially variable genes (SVGs) is a key step in the analysis of spatially resolved transcriptomics data. SVGs provide biological...
