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1. Osteocyte-derived sclerostin impairs cognitive function during ageing and Alzheimer’s disease progression

   Ageing increases susceptibility to neurodegenerative disorders, such as Alzheimer’s disease (AD). Serum levels of sclerostin, an osteocyte-derived...

   Tianshu Shi, Siyu Shen, ... Baosheng Guo in Nature Metabolism

   Article 26 February 2024
   

2. Breast carcinoma-amplified sequence 2 regulates adult neurogenesis via β-catenin

   Background

   Breast carcinoma-amplified sequence 2 (BCAS2) regulates β-catenin gene splicing. The conditional knockout of BCAS2 expression in the...

   Hsin-Hsiung Chen, Hao-Yu Lu, ... Show-Li Chen in Stem Cell Research & Therapy

   Article Open access 11 April 2022
   

3. Expansion spatial transcriptomics

   Capture array-based spatial transcriptomics methods have been widely used to resolve gene expression in tissues; however, their spatial resolution is...

   Yuhang Fan, Žaneta Andrusivová, ... Bo Wang in Nature Methods

   Article 22 June 2023
   

4. Color Hippocampus Image Segmentation Using Quantum Inspired Firefly Algorithm and Merging of Channel-Wise Optimums

   Color image segmentation is essential for medical image processing to figure out the cells, tissues, lesion areas, etc. The hippocampus is an...

   Alokeparna Choudhury, Sourav Samanta, ... Oishila Bandyopadhyay in Bioinformatics and Biomedical Engineering

   Conference paper 2023
   

5. Structural Organization of Astrocytes in the Subgranular Zone of the Rabbit Hippocampal Dentate Fascia

   Neurogenesis in the subgranular zone (SGZ) of the mammalian hippocampus is well known to occur throughout the life span. Astrocytes in this...

   E. G. Sukhorukova, O. V. Kirik, ... D. E. Korzhevskii in Journal of Evolutionary Biochemistry and Physiology

   Article 01 March 2019

6. Neuron Navigator 1 (Nav1) regulates the response to cocaine in mice

   Genetic variation accounts for much of the risk for develo** a substance use disorder, but the underlying genetic factors and their genetic...

   Jared R. Bagley, Yalun Tan, ... Gary Peltz in Communications Biology

   Article Open access 18 October 2023
   

7. Zinc Ameliorates Nogo-A Receptor and Osteocalcin Gene Expression in Memory-Sensitive Rat Hippocampus Impaired by Intracerebroventricular Injection of Streptozotocin

   Metabolic dysfunction is a critical step in the etiopathogenesis of Alzheimer’s disease. In this progressive neurological disorder, impaired zinc...

   Haluk Gumus, Saltuk Bugra Baltaci, ... Abdulkerim Kasim Baltaci in Biological Trace Element Research

   Article 03 September 2022
   

8. Using Pre-Clinical Studies to Explore the Potential Clinical Uses of Exosomes Secreted from Induced Pluripotent Stem Cell-Derived Mesenchymal Stem cells

   Recent studies of exosomes derived from mesenchymal stem cells (MSCs) have indicated high potential clinical applications in many diseases. However,...

   Andrew Kailin Zhou, Eric Jou, ... Baoqiang Guo in Tissue Engineering and Regenerative Medicine

   Article Open access 31 August 2023
   

9. SHANK family on stem cell fate and development

   SH3 and multiple ankyrin repeat domains protein (SHANK) 1, SHANK2, and SHANK3 encode a family of postsynaptic scaffolding proteins present at...

   Xu Liu, Mengmeng Yuan, ... Yue Li in Cell Death & Disease

   Article Open access 18 October 2022
   

10. Exploratory and Locomotor Activity in Mice Following Selective Lesions of the Hippocampus: Effects of Lesion Site and Open Field Arena Size

    Abstract

    The present study showed arena size-dependent effects on the impairment of locomotor activity and rearing after lesions of caudal hippocampus...

    P. A. Kuptsov, R. M. J. Deacon, ... M. G. Pleskacheva in Journal of Evolutionary Biochemistry and Physiology

    Article 01 July 2023
    

11. Deep generative modeling of transcriptional dynamics for RNA velocity analysis in single cells

    RNA velocity has been rapidly adopted to guide interpretation of transcriptional dynamics in snapshot single-cell data; however, current approaches...

    Adam Gayoso, Philipp Weiler, ... Nir Yosef in Nature Methods

    Article Open access 21 September 2023
    

12. Cells of Cerebrovascular Endothelium and Perivascular Astroglia in the Regulation of Neurogenesis

    Abstract

    The blood–brain barrier (BBB) is a constellation of cells within the neurovascular unit of the brain that perform the barrier function, being...

    E. A. Teplyashina, Ya. V. Gorina, ... A. B. Salmina in Journal of Evolutionary Biochemistry and Physiology

    Article 01 May 2022
    

13. Cerebral Semaphorin3D is a novel risk factor for age-associated cognitive impairment

    Background

    We previously reported that miR-195 exerts neuroprotection by inhibiting Sema3A and cerebral miR-195 levels decreased with age, both of...

    Chien-Yuan Chen, Yung-Mei Chao, ... Suh-Hang H. Juo in Cell Communication and Signaling

    Article Open access 14 June 2023
    

14. The Role of Stem Cells in Exercise-Enhanced Organogenesis and Regeneration

    The beneficial effect of exercise on the whole body is well-known, and recent evidence suggests that exercise could enhance tissue genesis and...

    Chang Liu, **nying Wu, ... Junjie **ao in Handbook of Stem Cell Applications

    Living reference work entry 2023
    

15. Hippocampal BMP signaling as a common pathway for antidepressant action

    The benefits of current treatments for depression are limited by low response rates, delayed therapeutic effects, and multiple side effects....

    Elif Tunc-Ozcan, Sarah M. Brooker, ... John A. Kessler in Cellular and Molecular Life Sciences

    Article 22 December 2021
    

16. Mettl1-mediated internal m⁷G methylation of Sptbn2 mRNA elicits neurogenesis and anti-alzheimer’s disease

    Background

    N ⁷ -methylguanosine (m ⁷ G) is one of the most conserved modifications in nucleosides impacting mRNA export, splicing, and translation....

    Qingfeng Li, Hui Liu, ... Aiguo Xuan in Cell & Bioscience

    Article Open access 01 October 2023
    

17. WWC1/2 regulate spinogenesis and cognition in mice by stabilizing AMOT

    WWC1 regulates episodic learning and memory, and genetic nucleotide polymorphism of WWC1 is associated with neurodegenerative diseases such as...

    Runyi Cao, Rui Zhu, ... Fa-**ng Yu in Cell Death & Disease

    Article Open access 01 August 2023
    

18. S100A6 as a Constituent and Potential Marker of Adult and Cancer Stem Cells

    Adult or tissue stem cells are present in various tissues of the organism where they reside in a specific environment called the niche. Owing to...

    Wiesława Leśniak, Anna Filipek in Stem Cell Reviews and Reports

    Article 07 July 2022
    

19. Involvement of isoproterenol-induced intracellular Zn²⁺ dynamics in the basolateral amygdala in conditioned fear memory

    Beta-adrenergic receptors in the basolateral amygdala play an essential role in fear memory, while the physiological role of intracellular Zn ²⁺ ...

    Ryusei Itoh, Yudai Ishikawa, ... Atsushi Takeda in BioMetals

    Article 18 July 2022
    

20. MNMST: topology of cell networks leverages identification of spatial domains from spatial transcriptomics data

    Advances in spatial transcriptomics provide an unprecedented opportunity to reveal the structure and function of biology systems. However, current...

    Yu Wang, Zaiyi Liu, **aoke Ma in Genome Biology

    Article Open access 23 May 2024