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Insight into the pathophysiological advances and molecular mechanisms underlying cerebral stroke: current status
Molecular pathways involved in cerebral stroke are diverse. The major pathophysiological events that are observed in stroke comprises of...
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Human platelet lysate stimulates neurotrophic properties of human adipose-derived stem cells better than Schwann cell-like cells
BackgroundTrauma-associated peripheral nerve injury is a widespread clinical problem causing sensory and motor disabilities. Schwann cells (SCs)...
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Pharmaceutical and nutraceutical potential of natural bioactive pigment: astaxanthin
Astaxanthin (3,3′-dihydroxy-β,β-carotene-4,4′-dione) is an orange-red, lipophilic keto-carotenoid pigment. It is majorly found in marine ecosystems...
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State of the Retina and Optic Nerve in 21-Day Head-Down Tilt Bed Rest
AbstractStudies in conditions of head-down tilt bed rest (HDTBR) are widely used experiments that imitate redistribution of body fluids similar to...
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Modeling the impact of thoracic pressure on intracranial pressure
A potential contribution to the progression of Spaceflight Associated Neuro-ocular Syndrome is the thoracic-to-spinal dural sac transmural pressure...
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Zeb1-controlled metabolic plasticity enables remodeling of chromatin accessibility in the development of neuroendocrine prostate cancer
Cell plasticity has been found to play a critical role in tumor progression and therapy resistance. However, our understanding of the characteristics...
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The neuroprotective roles of Dietary Micronutrients on Parkinson’s disease: a review
Parkinson’s disease (PD) is a prevalent elderly neurodegenerative disease. The nature of PD is strongly bounded with certain cellular processes,...
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Utilizing Carbon Ions to Treat Medulloblastomas that Exhibit Chromothripsis
Purpose of ReviewNovel radiation therapies with accelerated charged particles such as protons and carbon ions have shown encouraging results in...
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Intranasal human-recombinant NGF administration improves outcome in children with post-traumatic unresponsive wakefulness syndrome
BackgroundSevere traumatic brain injury (TBI) is one of the most dramatic events in pediatric age and, despite advanced neuro-intensive care, the...
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Assessing Mechanical Properties of Stored Potato Tubers Using Biospeckle Imaging: Reference Tests and Biospeckle Activity Analysis
The current study proposes a novel approach for assessing the effect of storage on potato tuber texture using biospeckle imaging. Agria potato tubers...
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Expression of polyamines and its association with GnRH-I in the hypothalamus during aging in rodent model
GnRH-I and GnIH are the key neuropeptides that regulate the hypothalamic–pituitary–gonadal axis in mammals during aging. Polyamines are important...
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Yucca schidigera Extract Mitigates the Oxidative Damages, Inflammation, and Neurochemical Impairments in the Brains of Quails Exposed to Lead
The present study explored the neurotoxic impacts of lead (Pb) and the potential alleviating effect of Yucca schidigera extract (YSE) in Japanese...
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Emerging concepts in the treatment of optic neuritis: mesenchymal stem cell-derived extracellular vesicles
BackgroundOptic neuritis (ON) is frequently encountered in multiple sclerosis, neuromyelitis optica spectrum disorder, anti-myelin oligodendrocyte...
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Unsaturated Hydraulic Conductivity Prediction Using Artificial Intelligence and Multiple Linear Regression Models in Biochar Amended Sandy Clay Loam Soil
Improved productivity of crops grown in biochar amended soils largely depend on the unsaturated hydraulic conductivity (K (q)) and moisture content...
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Therapeutic potential of low dose ionizing radiation against cancer, dementia, and diabetes: evidences from epidemiological, clinical, and preclinical studies
The growing use of ionizing radiation (IR)-based diagnostic and treatment methods has been linked to increasing chronic diseases among patients and...
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Edible Mushrooms as Neuro-nutraceuticals: Basis of Therapeutics
Mushrooms, the macro-fungi with distinctive fruiting bodies and mycelia, are valued throughout the world not only for their nutritive values but also...
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Taurine protects dopaminergic neurons in paraquat-induced Parkinson’s disease mouse model through PI3K/Akt signaling pathways
Taurine (Tau) is one of the most abundant amino acids in the brain and regulates physiological functions in the central nervous system, including...
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Towards physiologically relevant human pluripotent stem cell (hPSC) models of Parkinson’s disease
The derivation of human embryonic stem cells followed by the discovery of induced pluripotent stem cells and leaps in genome editing approaches have...
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Loss of Dip2b leads to abnormal neural differentiation from mESCs
BackgroundDisco-interacting protein 2 homolog B is a member of the Dip2 family encoded by the Dip2b gene. Dip2b is widely expressed in neuro-related...
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Clinical–Neurobiological Correlations in Female Adolescents with Non-Suicidal Self-Injurious Behavior
AbstractThe relationships of quantitative clinical, EEG, and neuroimmunological parameters were analyzed in 40 female adolescent patients with...