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Dying in self-defence: a comparative overview of immunogenic cell death signalling in animals and plants
Host organisms utilise a range of genetically encoded cell death programmes in response to pathogen challenge. Host cell death can restrict pathogen...
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RNA helicase DDX3X modulates herpes simplex virus 1 nuclear egress
DDX3X is a mammalian RNA helicase that regulates RNA metabolism, cancers, innate immunity and several RNA viruses. We discovered that herpes simplex...
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Isolation and identification of bubaline herpesvirus 1 (BuHV-1) from latently infected water buffalo (Bubalus bubalis) from Iran
In order to isolate buffaloes herpesvirus 1 (BuHV-1) from latently infected water buffalo ( Bubalus bubalis ), 16 buffalo heifers were selected from a...
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Identification and characterization of lymphocystis disease virus (LCDV) from Indian glassy fish (Parambassis ranga Hamilton, 1822) in Iran
Lymphocystis disease (LCD) is a self-limiting viral disease characterized by hypertrophy of fibroblastic cells in connective tissues of fishes. Upon...
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Schreibers’ Bent-Winged Bat Miniopterus schreibersii (Kuhl, 1817)
This comprehensive species-specific chapter covers all aspects of the mammalian biology, including paleontology, physiology, genetics, reproduction... -
Ivermectin antiviral activity against Varicellovirus bovinealpha 1: assessment of intracellular drug accumulation in virus-infected cells
Varicellovirus bovinealpha 1 (formerly b ovine alphaherpesvirus type 1 , BoAHV-1) is associated with several syndromes in cattle, including respiratory...
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SARS-CoV-2 helicase might interfere with cellular nonsense-mediated RNA decay: insights from a bioinformatics study
BackgroundViruses employ diverse strategies to interfere with host defense mechanisms, including the production of proteins that mimic or resemble...
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Protective effect of Platycodon grandiflorus polysaccharide on apoptosis and mitochondrial damage induced by pseudorabies virus in PK-15 cells
Previous studies have confirmed that Platycodon grandiflorus polysaccharide (PGPS t ) has the effects of regulating immunity and anti-apoptosis, but...
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Viral Genomic DNA Packaging Machinery
Tailed double-stranded DNA bacteriophage employs a protein terminase motor to package their genome into a preformed protein shell—a system shared... -
Comparative genomics and integrated system biology approach unveiled undirected phylogeny patterns, mutational hotspots, functional patterns, and molecule repurposing for monkeypox virus
Monkeypox is a viral zoonosis with symptoms that are reminiscent of those experienced in previous smallpox cases. The GSAID database (Global...
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Remodeling of host membranes during herpesvirus assembly and egress
Many viruses, enveloped or non-enveloped, remodel host membrane structures for their replication, assembly and escape from host cells. Herpesviruses...
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KSHV transactivator-derived small peptide traps coactivators to attenuate MYC and inhibits leukemia and lymphoma cell growth
In herpesvirus replicating cells, host cell gene transcription is frequently down-regulated because important transcriptional apparatuses are...
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Opportunities and obstacles for the melanoma immunotherapy using T cell and chimeric antigen receptor T (CAR-T) applications: a literature review
Chimeric antigen receptor T (CAR-T) cell therapy procedure includes taking personal T cells and processing or genetic engineering using specific...
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Myotis nattereri Species Complex (M. nattereri, M. crypticus, and M. escalerai)
This comprehensive species-specific chapter covers all aspects of the mammalian biology, including paleontology, physiology, genetics, reproduction... -
Myotis nattereri Species Complex (M. nattereri, M. crypticus, and M. escalerai)
This comprehensive species-specific chapter covers all aspects of the mammalian biology, including paleontology, physiology, genetics, reproduction... -
Characterization of oral virome and microbiome revealed distinctive microbiome disruptions in paediatric patients with hand, foot and mouth disease
While the underlying determinants are unclear, hand, foot and mouth disease (HFMD) presents a wide spectrum of clinical manifestations with varying...
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Freisetzung von Herpesviruskapsiden aus dem Kern
Herpesvirus nucleocapsids are formed in the nucleus but mature into virions in the cytoplasm. Canonical nucleo-cytoplasmic transport is restricted to...