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A heat-shock response regulated by the PfAP2-HS transcription factor protects human malaria parasites from febrile temperatures
Periodic fever is a characteristic clinical feature of human malaria, but how parasites survive febrile episodes is not known. Although the genomes...
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Cell surface heat shock protein-mediated entry of tumor cell-adapted rotavirus into U-937 cells
Rotaviruses infect cells by binding to specific cell surface molecules including gangliosides, heat shock protein cognate protein 70 (Hsc70), and...
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Effects of HSP inducers on the gene expression of Heat Shock Proteins (HSPs) in cells extracted from sterlet sturgeon under temperature stress with antioxidant and immunity responses
Global warming has profound effects on the living conditions and metabolism of organisms, including fish. The metabolic rate of fish increases as the...
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Expression patterns of heat-shock genes during stopover and the trade-off between refueling and stress response in a passerine migrant
Migrating birds are often exposed to variable environments and face a multitude of stress exposures along their long-distance flights. During...
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Maize heat shock proteins—prospection, validation, categorization and in silico analysis of the different ZmHSP families
Among the plant molecular mechanisms capable of effectively mitigating the effects of adverse weather conditions, the heat shock proteins (HSPs), a...
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The abundance and localization of heat shock proteins (HSP)-60, -70, and -90 in the oviductal ampulla of hamadryas baboon (Papio hamadryas) during the menstrual cycle
The presence of HSPs in female reproductive and their relationship with the steroid hormone fluctuation have been reported in several mammals but not...
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Knockout of Hsp70 Genes Modulates Age-Related Transcriptomic Changes in Leg Muscles and Reduces the Locomotion Speed and Lifespan of Drosophila melanogaster
This study investigated the effect of knockout of six Hsp70 genes (orthologues of the mammalian genes Hspa1a , Hspa1b , Hspa2, and Hspa8 ) on...
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Effects of small heat shock proteins from thermotolerant bacteria on the stress resistance of Escherichia coli to temperature, pH, and hyperosmolarity
Small heat shock proteins (HSPs), such as HSP20, represent cellular thermal resistance mechanisms, to avoid protein aggregation at elevated...
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Heat shock factor 1 directly regulates transsulfuration pathway to promote prostate cancer proliferation and survival
There are limited therapeutic options for patients with advanced prostate cancer (PCa). We previously found that heat shock factor 1 (HSF1)...
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Hsp104p: a protein disaggregase
All newly synthesized proteins must fold to their correct native conformation in order to function. That protein folding in the crowded...
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Heat shock factor 1 suppression induces spindle abnormalities and sensitizes cells to antimitotic drugs
BackgroundHeat shock factor 1 (HSF1) is the master regulator of the heat shock response and supports malignant cell transformation. Recent work has...
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Analyzing the regulatory role of heat shock transcription factors in plant heat stress tolerance: a brief appraisal
An increase in ambient temperature throughout the twenty-first century has been described as a “worldwide threat” for crop production. Due to their...
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Heat shock proteins with an emphasis on HSP 60
Heat shock phenomenon is a process by which cells express a set of proteins called heat shock proteins (HSPs) against heat stress. HSPs include...
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Contemplation of protein–protein interactions for salt tolerance in rice mutant lines
Proteome analyses of two contrasting mutant lines and their parent revealed responsive proteins in salt stress. The tandem mass spectrometry analysis...
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Hsp60/10 and sHsp families of heat shock protein genes in rainbow trout (Oncorhynchus mykiss) and their expression under heat stress
Heat shock proteins (Hsps) are highly conserved proteins whose expression can be induced by high temperature and play an important role in a variety...
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Plasticity in depth selection behavior and heat shock proteins in Daphnia
Habitat selection behavior by aquatic and terrestrial animals is influenced by both abiotic (e.g., temperature) and biotic (e.g., threat from...
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Conformational dynamics of free and membrane-bound human Hsp70 in model cytosolic and endo-lysosomal environments
The binding of the major stress-inducible human 70-kDa heat shock protein (Hsp70) to the anionic phospholipid bis-(monoacylglycero)-phosphate (BMP)...
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Transplantation of Heat-Shock Preconditioned Neural Stem/Progenitor Cells Combined with RGD-Functionalised Hydrogel Promotes Spinal Cord Functional Recovery in a Rat Hemi-Transection Model
BackgroundNeural stem/progenitor cell (NSPC) transplantation in spinal cord injury (SCI) is a potential treatment that supports regeneration by...
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The protein phosphatase-2A subunit PR130 is involved in the formation of cytotoxic protein aggregates in pancreatic ductal adenocarcinoma cells
As a major source of cellular serine and threonine phosphatase activity, protein phosphatase-2A (PP2A) modulates signaling pathways in health and...
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Evaluation of Morphological Malformities and hsp70 Gene Response on Aristolochic Acid Exposed Neocardina davidi (Red Shrimp)
AbstractIn our study, we investigated morphological abnormalities and overexpression of one of the stress genes ( hsp70 ) at different concentrations...
