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Sodium butyrate alleviates deoxynivalenol-induced hepatic cholesterol metabolic dysfunction via RORγ-mediated histone acetylation modification in weaning piglets
BackgroundCholesterol is an essential component of lipid rafts in cell plasma membrane, which exerts a hepatoprotective role against mycotoxin...
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Leveraging host-genetics and gut microbiota to determine immunocompetence in pigs
BackgroundThe gut microbiota influences host performance playing a relevant role in homeostasis and function of the immune system. The aim of the...
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Genotype-by-environment interactions for reproduction, body composition, and growth traits in maternal-line pigs based on single-step genomic reaction norms
BackgroundThere is an increasing need to account for genotype-by-environment (G × E) interactions in livestock breeding programs to improve...
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Estimation of genetic parameters and inbreeding depression in Piau pig breed
This study is aimed at estimating genetic parameters, effective population size, inbreeding, and inbreeding depression for birth weight, weaning...
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Compositional analysis of the tonsil microbiota in relationship to Streptococcus suis disease in nursery pigs in Ontario
BackgroundThe tonsil of the soft palate in pigs is the colonization site of both commensal and pathogenic microbial agents. Streptococcus suis ...
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Ages of weaning influence the gut microbiota diversity and function in Chongming white goats
AbstractTo study the effect of weaning age on the gut microbiota diversity in the lambs of Chongming white goats, fresh feces from the lambs weaned...
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Trace amounts of antibiotic altered metabolomic and microbial profiles of weaned pigs infected with a pathogenic E. coli
BackgroundOur previous study has shown that supplementation of trace amounts of antibiotic exacerbated the detrimental effects of enterotoxigenic E....
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Gut microbiota and host genetics contribute to the phenotypic variation of digestive and feed efficiency traits in growing pigs fed a conventional and a high fiber diet
BackgroundBreeding pigs that can efficiently digest alternative diets with increased fiber content is a viable strategy to mitigate the feed cost in...
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Repeatability of endocrine traits and dominance rank in female guinea pigs
BackgroundGlucocorticoids (e.g. cortisol) are associated with variation in social behavior, and previous studies have linked baseline as well as...
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A transgene-free method for rapid and efficient generation of precisely edited pigs without monoclonal selection
Gene-edited pigs for agricultural and biomedical applications are typically generated using somatic cell nuclear transfer (SCNT). However, SCNT...
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Motivation matters: lighter littermates of the domestic cat compete more successfully for meat at weaning
AbstractWidespread recognition of the contribution of individual differences in behavioral phenotype to evolutionary processes raises questions as to...
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Alternatives to antibiotics in pig production: looking through the lens of immunophysiology
In the livestock production system, the evolution of porcine gut microecology is consistent with the idea of “The Hygiene Hypothesis” in humans. I.e. ,...
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Map** and analysis of a spatiotemporal H3K27ac and gene expression spectrum in pigs
The limited knowledge of genomic noncoding and regulatory regions has restricted our ability to decipher the genetic mechanisms underlying complex...
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Fecal microbial composition and functional diversity of Wuzhishan pigs at different growth stages
The mammalian gut microbiome participates in almost all life processes in the host. In addition to diet, the breed is the main factor affecting...
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Sow performance in response to natural betaine fed during lactation and post-weaning during summer and non-summer months
BackgroundTwo studies were conducted to evaluate the effects of dietary natural betaine on sow reproductive performance during summer (Exp. 1) and...
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Pioneering gut health improvements in piglets with phytogenic feed additives
AbstractThis research investigates the effects of phytogenic feed additives (PFAs) on the growth performance, gut microbial community, and microbial...
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Dietary branched-chain amino acids modulate the dynamics of calcium absorption and reabsorption in protein-restricted pigs
BackgroundVery low-protein (VLP) diets negatively impact calcium (Ca) metabolism and absorption. The objective of this study was to investigate the...
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Tannic acid prevents post-weaning diarrhea by improving intestinal barrier integrity and function in weaned piglets
BackgroundTannic acid (TA) is potential to reduce diarrhea in weaning pigs, but knowledge about the influence of TA on intestinal barrier integrity...
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Shifts in energy allocation and reproduction in response to temperature in a small precocial mammal
BackgroundSpecies adjust to changes in temperature and the accompanying reduction in resource availability during the annual cycle by shifts in...
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Quantitative analysis of the blood transcriptome of young healthy pigs and its relationship with subsequent disease resilience
BackgroundDisease resilience, which is the ability of an animal to maintain performance under disease, is important for pigs in commercial herds,...
