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Acute hypoxia elevates arginase 2 and induces polyamine stress response in zebrafish via evolutionarily conserved mechanism
Living organisms repeatedly encounter stressful events and apply various strategies to survive. Polyamines are omnipresent bioactive molecules with...
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ASS1 metabolically contributes to the nuclear and cytosolic p53-mediated DNA damage response
Downregulation of the urea cycle enzyme argininosuccinate synthase (ASS1) in multiple tumors is associated with a poor prognosis partly because of...
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Urea-aromatic interactions in biology
Noncovalent interactions are key determinants in both chemical and biological processes. Among such processes, the hydrophobic interactions play an...
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Fungi and Nitrogen Cycle: Symbiotic Relationship, Mechanism and Significance
Fungi are integral components of any natural ecosystem and play a significant role in maintaining nitrogen cycle. Nitrogen is the essential... -
Nitrogen supply associated with rhizobacteria in the first productive cycle of Marandu grass
The rhizobacteria of genus Azospirillum and Bacillus are effective at fixing atmospheric nitrogen, promote plant growth and can largely contribute to...
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Ammonia-oxidizing bacteria and archaea exhibit differential nitrogen source preferences
Ammonia-oxidizing microorganisms (AOM) contribute to one of the largest nitrogen fluxes in the global nitrogen budget. Four distinct lineages of AOM:...
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Techno-economic and Life Cycle Assessments of Microbial Process in Renewable Energy Production
Energy security, environmental concerns, and the increasing demand of a growing population present opportunities for adopting alternative pathways... -
Search for Metabolomic Markers of Hypertensive Conditions of Different Genesis: Experimental Study
AbstractA personalized approach to the diagnosis and treatment of arterial hypertension requires a comprehensive analysis of the...
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Compositional Shifts and Assembly in Rhizosphere-Associated Fungal Microbiota Throughout the Life Cycle of Japonica Rice Under Increased Nitrogen Fertilization
Soil fungal microbiomes facilitate a range of beneficial functions for their host plants, and rhizosphere fungal community composition, richness, and...
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Wnt/β-catenin signaling regulates amino acid metabolism through the suppression of CEBPA and FOXA1 in liver cancer cells
Deregulation of the Wnt/β-catenin pathway is associated with the development of human cancer including colorectal and liver cancer. Although we...
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The Impact of Different Fertilizers on Physiological and Biochemical Attributes of Soybean Plants Grown in Saline and Non-Saline Soils
Soybean is an important cash crop; however, its productivity is significantly hampered by salinity. Therefore, it is crucial to apply fertilizer...
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Transcriptome Analysis of a Wine Yeast Strain with a Deletion of the CAR1 Arginase Gene
Abstract —Ethyl carbamate, a potential carcinogen, is formed in wine as a result of a chemical reaction between ethanol and urea during fermentation...
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Effects of urea on cell growth and physiological response in pigment biosynthesis in mixotrophic Chromochloris zofingiensis
The mixotrophic cultivation of Chromochloris zofingiensis (Chlorophyta, Trebouxiophyceae) under various urea concentrations was investigated for...
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Exogenous Coumarin Decreases Phytotoxic Effects of Manganese by Regulating Ascorbate–Glutathione Cycle and Glyoxalase System to Improve Photosynthesis and Nutrient Acquisition in Sesame (Sesamum indicum L.)
Coumarin (COU) is an essential phenolic compound safeguarding plants under environmental constraints. Coumarin-induced salinity tolerance is reported...
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Investigation of the effects of urea cycle amino acids on the expression of ALB and CEBPB in the human hepatocellular carcinoma cell line FLC-4
Cell lines are powerful tools for research into liver function at the molecular level. However, they are generally unsuitable for rigorously...
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A review of dietary approaches for ammonia toxicity remediation in fish
We reviewed available data regarding the benefits of feed additives for mitigation of ammonia toxicity in fish. We first emphasized the toxic effects...
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Nitrous oxide emissions after struvite application in relation to soil P status
PurposeAlthough struvite (MgNH 4 PO 4 ·6H 2 O) is mostly considered to be a novel phosphorus (P) fertiliser, it does contain a significant amount of...
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Identification of a novel homozygous intron 3 splice site (A>T) mutation in the ARG1 gene in cerebral palsy pediatric cases from Odisha, India
BackgroundArginase enzyme is essential for the catalysis of the last step of the urea cycle, resulting in the conversion of l -arginine to l -ornithine...
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Cell signalling compound improves pasture and livestock productivity and the environment
A biogenic agricultural compound enables pasture to synthesise more soluble sugars and delivers benefits attributable to bioactive molecules:...
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Effects of the Combined Application of Nitrogen Fertilizer and 2,4-D on Nitrification Ammonia Oxidizers and Herbicide Bioavailability in a Volcanic Soil. A Microcosm Study
Purpose2,4-D (2,4-dichlorophenoxy acetic acid) is an herbicide used in weed control worldwide; however, there is no information regarding its effects...