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1. Contextual determinants of TGFβ action in development, immunity and cancer

   Few cell signals match the impact of the transforming growth factor-β (TGFβ) family in metazoan biology. TGFβ cytokines regulate cell fate decisions...

   Charles J. David, Joan Massagué in Nature Reviews Molecular Cell Biology

   Article 11 April 2018
   

2. SMAD family member 1 (MADH1; SMAD1) MADH5 (SMAD5); MADH9 (SMAD9; SMAD8)

   in Science-Business eXchange

   Article 30 October 2014

3. Characterizations of PMCA2-interacting complex and its role as a calcium oxalate crystal-binding protein

   Three isoforms of plasma membrane Ca ²⁺ -ATPase (PMCA) are expressed in the kidney. While PMCA1 and PMCA4 play major role in regulating Ca ²⁺ ...

   Arada Vinaiphat, Visith Thongboonkerd in Cellular and Molecular Life Sciences

   Article 30 October 2017
   

4. ALK1 signaling in development and disease: new paradigms

   Activin A receptor like type 1 (ALK1) is a transmembrane serine/threonine receptor kinase in the transforming growth factor-beta receptor family that...

   Beth L. Roman, Andrew P. Hinck in Cellular and Molecular Life Sciences

   Article 04 September 2017
   

5. BMP-SMAD signalling output is highly regionalized in cardiovascular and lymphatic endothelial networks

   Background

   Bone morphogenetic protein (BMP) signalling has emerged as a fundamental pathway in endothelial cell biology and deregulation of this...

   Karen Beets, Michael W. Staring, ... An Zwijsen in BMC Developmental Biology

   Article Open access 10 October 2016
   

6. LNDriver: identifying driver genes by integrating mutation and expression data based on gene-gene interaction network

   Background

   Cancer is a complex disease which is characterized by the accumulation of genetic alterations during the patient’s lifetime. With the...

   Pi-**g Wei, Di Zhang, ... Chun-Hou Zheng in BMC Bioinformatics

   Article Open access 23 December 2016
   

7. AID/APOBEC-network reconstruction identifies pathways associated with survival in ovarian cancer

   Background

   Building up of pathway-/disease-relevant signatures provides a persuasive tool for understanding the functional relevance of gene...

   Martin Svoboda, Anastasia Meshcheryakova, ... Diana Mechtcheriakova in BMC Genomics

   Article Open access 16 August 2016
   

8. Determination of dosage compensation and comparison of gene expression in a triploid hybrid fish

   Background

   Polyploidy and hybridization are both recognized as major forces in evolution. Most of our current knowledge about differences in gene...

   Li Ren, Chenchen Tang, ... Shaojun Liu in BMC Genomics

   Article Open access 05 January 2017
   

9. Transcription factor ZNF25 is associated with osteoblast differentiation of human skeletal stem cells

   Background

   The differentiation of human bone marrow derived skeletal stem cells (known as human bone marrow stromal or mesenchymal stem cells, hMSCs)...

   Natalie A. Twine, Linda Harkness, ... Marc R. Wilkins in BMC Genomics

   Article Open access 04 November 2016
   

10. Comparison of microarray expression profiles between follicular variant of papillary thyroid carcinomas and follicular adenomas of the thyroid

    Background

    Follicular variant of papillary thyroid carcinoma (FVPTC) and follicular adenoma (FA) are histologically closely related tumors and...

    Hans-Juergen Schulten, Zuhoor Al-Mansouri, ... Jaudah Al-Maghrabi in BMC Genomics

    Article Open access 15 January 2015
    

11. Identification of microRNA and target gene associated with marbling score in Korean cattle (Hanwoo)

    Marbling is a crucial characteristic in meat quality assessment. In the search for a genetic basis of meat quality, a large number of gene analyses...

    Jiyeon Seong, Hyojeong Yoon, Hong Sik Kong in Genes & Genomics

    Article 19 March 2016
    

12. A network map of Interleukin-10 signaling pathway

    Interleukin-10 (IL-10) is an anti-inflammatory cytokine with important immunoregulatory functions. It is primarily secreted by antigen-presenting...

    Renu Verma, Lavanya Balakrishnan, ... Subramanian Shankar in Journal of Cell Communication and Signaling

    Article 08 August 2015
    

13. On signaling pathways: hematopoietic stem cell specification from hemogenic endothelium

    Hematopoietic stem cells (HSCs) are specified and generated during the embryonic development and have remarkable potential to replenish the full set...

    Yan Long, He Huang in Science China Life Sciences

    Article Open access 26 November 2015

14. The transcriptome of metamorphosing flatfish

    Background

    Flatfish metamorphosis denotes the extraordinary transformation of a symmetric pelagic larva into an asymmetric benthic juvenile....

    Ricardo N. Alves, Ana S. Gomes, ... Deborah M. Power in BMC Genomics

    Article Open access 27 May 2016
    

15. Detection and replication of QTL underlying resistance to gastrointestinal nematodes in adult sheep using the ovine 50K SNP array

    Background

    Persistence of gastrointestinal nematode (GIN) infection and the related control methods have major impacts on the sheep industry...

    Marina Atlija, Juan-Jose Arranz, ... Beatriz Gutiérrez-Gil in Genetics Selection Evolution

    Article Open access 20 January 2016
    

16. MicroRNA expression signature for Satb2-induced osteogenic differentiation in bone marrow stromal cells

    Satb2 acts as a potent transcription factor to promote osteoblast differentiation and bone regeneration. Recently, microRNAs (miRNA) have been...

    Yiming Gong, Fei Xu, ... Youcheng Yu in Molecular and Cellular Biochemistry

    Article 12 November 2013
    

17. RETRACTED ARTICLE: Identification of genes associated with the differentiation potential of adipose-derived stem cells to osteocytes or myocytes

    Adipose-derived stem cells (ADSCs) have been considered as the optimal cells for regenerative medicine because ADSCs have the...

    Yizhong Ren, Changxu Han, ... Dianming Jiang in Molecular and Cellular Biochemistry

    Article 11 November 2014
    

18. MicroRNAs involved in bone formation

    During skeletal development, mesenchymal progenitor cells undergo a multistage differentiation process in which they proliferate and become bone- and...

    Garyfallia Papaioannou, Fatemeh Mirzamohammadi, Tatsuya Kobayashi in Cellular and Molecular Life Sciences

    Article 10 August 2014

19. Combined analysis of chromosomal instabilities and gene expression for colon cancer progression inference

    Background

    Copy number alterations (CNAs) represent an important component of genetic variations. Such alterations are related with certain type of...

    Claudia Cava, Italo Zoppis, ... Marco Antoniotti in Journal of Clinical Bioinformatics

    Article Open access 24 January 2014
    

20. Flouride Promotes Viability and Differentiation of Osteoblast-Like Saos-2 Cells Via BMP/Smads Signaling Pathway

    The BMP/Smad signaling pathway plays an important role in the viability and differentiation of osteoblast; however, it is not clear whether this...

    Liangliang Huo, Kangkang Liu, ... Yanhui Gao in Biological Trace Element Research

    Article Open access 07 August 2013