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Viable and Heat-Killed Probiotic Strains Improve Oral Immunity by Elevating the IgA Concentration in the Oral Mucosa
Oral-nasal mucosal immunity plays a crucial role in protecting the body against bacterial and viral invasion. Safe probiotic products have been used...
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Effects of dietary supplementation of compound probiotics on growth, non-specific immunity, intestinal digestive enzyme, and microbiota of whitespotted conger (Conger myriaster) in recirculating aquaculture system
This study investigated the impact of compound probiotics on the growth performance, non-specific immunity, intestinal digestive enzyme, and...
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Effects of Dietary Supplementation with Lactobacillus acidophilus and Bacillus subtilis on Mucosal Immunity and Intestinal Barrier Are Associated with Its Modulation of Gut Metabolites and Microbiota in Late-Phase Laying Hens
We investigated the effects of dietary supplementation with Lactobacillus acidophilus and Bacillus subtilis on the intestinal immune response,...
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Cellular basis of enhanced humoral immunity to SARS-CoV-2 upon homologous or heterologous booster vaccination analyzed by single-cell immune profiling
SARS-CoV-2 vaccine booster dose can induce a robust humoral immune response, however, its cellular mechanisms remain elusive. Here, we investigated...
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Effects of dietary supplementation of gallic tanninc acid on growth, intestinal digestive enzymes activity, innate immunity, morphology, and microbial composition of Cyprinus carpio
In this study, we investigated the effects of gallic tannic acid (GTA) supplementation on the growth performance, intestinal digestive enzymes,...
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Histone demethylases in the regulation of immunity and inflammation
Pathogens or danger signals trigger the immune response. Moderate immune response activation removes pathogens and avoids excessive inflammation and...
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DExD/H-box helicases: multifunctional regulators in antiviral innate immunity
DExD/H-box helicases play critical roles in multiple cellular processes, including transcription, cellular RNA metabolism, translation, and...
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Role of probiotics on the immunity of Nile tilapia Oreochromis niloticus: a review
The development and intensification of Nile tilapia farming systems has happened together with ever increased use of antibiotics and therapeutants....
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Engineering of Chlamydomonas reinhardtii chloroplast for mucosal immunotherapeutic against Newcastle disease virus
Newcastle disease virus (NDV) is a devastating virus for the poultry industry, resulting in huge economic losses due to high morbidity and mortality....
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Feed-based bivalent vaccine upregulates expressions of immune-related genes in systemic and mucosal tissues of red hybrid tilapia (Oreochromis niloticus × O. mossambicus) against Streptococcus iniae and Aeromonas hydrophila
Streptococcus iniae and Aeromonas hydrophila are the two major pathogens of tilapia, and considered a significant problem with huge economic losses...
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Puerarin alleviates sleep disorders in aged mice related to repairing intestinal mucosal barrier
More and more evidence suggests that puerarin, a potential remedy for gut inflammation, may have an ameliorative effect on sleep disturbances....
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Plant Molecular Farming for Vaccine Development
Vaccines are effective tools for the prophylaxis of infectious diseases. Various diseases have been eradicated using vaccines, and the importance of... -
Role of Mucin 2 Glycoprotein and L-fucose in Interaction of Immunity and Microbiome within the Experimental Model of Inflammatory Bowel Disease
AbstractMany factors underlie the development of inflammatory bowel disease (IBD) in humans. In particular, imbalance of microbiota and thinning of...
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Isolation and characterization of autochthonous probiotics from skin mucus and their in vivo validation with dietary probiotic bacteria on growth performance and immunity of Labeo calbasu (Hamilton, 1822)
The present study was performed to isolate and identify antimicrobial bacteria from the skin mucus of Labeo calbasu and assess their effects as water...
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Potential effects of gut microbiota on host cancers: focus on immunity, DNA damage, cellular pathways, and anticancer therapy
The symbiotic bacteria that live in the human gut and the metabolites they produce have long influenced local and systemic physiological and...
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Intermittent administration of peracetic acid is a mild environmental stressor that elicits mucosal and systemic adaptive responses from Atlantic salmon post-smolts
BackgroundFish encounter oxidative stress several times during their lifetime, and it has a pervasive influence on their health and welfare. One of...
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Effects of dietary Mitracarpus scaber leaves extract on growth, physiological, antioxidants, and mucosal immune profiles of North African catfish, Clarias gariepinus, and resistance against Edwardsiella tarda infection
This study evaluated the effect of Mitracarpus scaber leaves extract (MSLE) as a dietary supplement on growth performance, physiological,...
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The effects of dietary L-carnitine supplementation in fish diet containing high corn gluten meal on immunity, lipid metabolism, and metabolomics in juvenile hybrid grouper (♀Epinephelus fuscoguttatus × ♂Epinephelus lanceolatus)
This study examined the effects of L-carnitine (LC) supplementation in corn gluten meal (CGM) diets for juvenile hybrid grouper on growth, immunity,...
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Pathogen-associated T follicular helper cell plasticity is critical in anti-viral immunity
T follicular helper (Tfh) cells are critical in providing help for B cells in the germinal center reaction. Tfh cell plasticity, especially with...
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A combined inactivated cholera and hepatitis A vaccine-induced potent protective immunity in a mouse model
AbstractCholera and hepatitis A are serious infections spread by consuming contaminated food or water. Vaccination is the most effective strategy to...