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Genome-Wide DNA Methylation Protocol for Epigenetics Studies
Epigenetic modification are heritable changes in gene expression not encoded by the DNA sequence therefore playing a significant role in a broad...
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DNA methylation of GDF-9 and GHR genes as epigenetic regulator of milk production in Egyptian Zaraibi goat
BackgroundDNA methylation is an epigenetic mechanism that takes place at gene promoters and a potent epigenetic marker to regulate gene expression.
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Diversity of individuals' methylation patterns to different moisture regimes in Einkorn wheat revealed by CRED-RA technique
Diploid species with desirable traits among wheat's wild relatives have a high potential for crop modification. DNA methylation is one of the...
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Detecting cell-of-origin and cancer-specific methylation features of cell-free DNA from Nanopore sequencing
The Oxford Nanopore (ONT) platform provides portable and rapid genome sequencing, and its ability to natively profile DNA methylation without complex...
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DNA methylation analysis of floral parts revealed dynamic changes during the development of homostylous Fagopyrum tataricum and heterostylous F. esculentum flowers
BackgroundProper flower development is essential for plant reproduction, a crucial aspect of the plant life cycle. This process involves precisely...
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Multi-tissue DNA methylation aging clocks for sea lions, walruses and seals
Age determination of wild animals, including pinnipeds, is critical for accurate population assessment and management. For most pinnipeds, current...
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Predicting active enhancers with DNA methylation and histone modification
BackgroundEnhancers play a crucial role in gene regulation, and some active enhancers produce noncoding RNAs known as enhancer RNAs (eRNAs)...
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Effects of maternal methyl donor intake during pregnancy on ileum methylation and function in an intrauterine growth restriction pig model
BackgroundIntrauterine growth retardation (IUGR) affects intestinal growth, morphology, and function, which leads to poor growth performance and high...
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Chromosomal aberrations and changes in the methylation patterns of Lactuca sativa L. (Asteraceae) exposed to carbon nanotubes
Carbon nanotubes (CNTs) are one of the most important nanomaterials, with applications in several areas. The exponential increase in the production...
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Dynamic roles of small RNAs and DNA methylation associated with heterosis in allotetraploid cotton (Gossypium hirsutum L.)
BackgroundHeterosis is a complex phenomenon wherein the hybrids outperform their parents. Understanding the underlying molecular mechanism by which...
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The effects of N6-methyladenosine RNA methylation on the nervous system
Epitranscriptomics, also known as “RNA epigenetics”, is a type of chemical modification that regulates RNA. RNA methylation is a significant...
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Profiling DNA Methylation in Human Naïve Pluripotent Stem Cells
DNA methylation represents one of the best characterized epigenetic modifications. In particular, global demethylation is a common feature of...
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Targeting PRMT9-mediated arginine methylation suppresses cancer stem cell maintenance and elicits cGAS-mediated anticancer immunity
Current anticancer therapies cannot eliminate all cancer cells, which hijack normal arginine methylation as a means to promote their maintenance via...
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Genome-wide DNA methylation profiling in differentiating Crohn’s disease from intestinal tuberculosis
BackgroundDifferential diagnosis of Crohn’s disease (CD) and intestinal tuberculosis (ITB) is still difficult in clinical pratice. DNA methylation...
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H3K4 methylation regulates development, DNA repair, and virulence in Mucorales
Mucorales are basal fungi that opportunistically cause a potentially fatal infection known as mucormycosis (black fungus disease), which poses a...
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Karma-EgDEF1 methylation in Elaeis guineensis clonal mother palms that produced high mantling rates in the second clonal generation
The mantled phenotype in oil palm is a somaclonal variant that can only be visibly detected when the plant reaches reproductive maturity, which is...
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Effects of stacking breeding on the methylome and transcriptome profile of transgenic rice with glyphosate tolerance
Main conclusionTranscriptomics and methylomics were used to identify the potential effects resulting from GM rice breeding stacks, which provided...
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Modulation of DNA/RNA Methylation Signaling Mediating Metabolic Homeostasis in Cancer
Nucleic acid methylation is a fundamental epigenetic mechanism that im**es upon several cellular attributes, including metabolism and energy...
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DNA methylation underpins the epigenomic landscape regulating genome transcription in Arabidopsis
BackgroundIt is challenging to determine the effect of DNA methylation on the epigenetic landscape and the function in higher organisms due to the...
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Fertilization by short-term stored sperm alters DNA methylation patterns at single-base resolution in common carp (Cyprinus carpio) embryos
Sperm after short-term storage in vitro is widely used for artificial fertilization in aquaculture. It has been shown that short-term storage affects...
