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Ultrashort wave diathermy inhibits pulmonary inflammation in mice with acute lung injury in a HSP70 independent way: a pilot study
BackgroundAcute lung injury (ALI) is a clinical syndrome characterized by pulmonary inflammation. Ultrashort wave diathermy (USWD) has been shown to...
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Genome-wide expression of the residual lung reacting to experimental Pneumonectomy
BackgroundAcute or chronic irreversible respiratory failure may occur in patients undergoing pneumonectomy. Aim of this study was to determine...
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Role of GSDM family members in airway epithelial cells of lung diseases: a systematic and comprehensive transcriptomic analysis
Gasdermin (GSDM) family, the key executioners of pyroptosis, play crucial roles in anti-pathogen and anti-tumor immunities, although little is known...
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Proteomic characterization of spontaneously regrowing spinal cord following injury in the teleost fish Apteronotus leptorhynchus, a regeneration-competent vertebrate
In adult mammals, spontaneous repair after spinal cord injury (SCI) is severely limited. By contrast, teleost fish successfully regenerate injured...
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Endothelial cell dynamics in sepsis-induced acute lung injury and acute respiratory distress syndrome: pathogenesis and therapeutic implications
Sepsis, a prevalent critical condition in clinics, continues to be the leading cause of death from infections and a global healthcare issue. Among...
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Mesenchymal Stem Cells for Bone and Cartilage Regeneration: State of the Art
Mesenchymal stem cells (MSCs) have essential applications in bone and cartilage regenerative medicine. Undifferentiated MSCs show a high...
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MiR-326-mediated overexpression of NFIB offsets TGF-β induced epithelial to mesenchymal transition and reverses lung fibrosis
Idiopathic Pulmonary Fibrosis (IPF) is a progressively fatal and incurable disease characterized by the loss of alveolar structures, increased...
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A new perspective on gut-lung axis affected through resident microbiome and their implications on immune response in respiratory diseases
The highly diverse microbial ecosystem of the human body colonizes the gastrointestinal tract has a profound impact on the host’s immune, metabolic,...
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Ferroptosis in lung cancer: a novel pathway regulating cell death and a promising target for drug therapy
Lung cancer is a common malignant tumor that occurs in the human body and poses a serious threat to human health and quality of life. The existing...
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Expansion of FGFR3-positive nucleus pulposus cells plays important roles in postnatal nucleus pulposus growth and regeneration
BackgroundIntervertebral disc degeneration (IVDD) can cause low back pain, a major public health concern. IVDD is characterized with loss of cells...
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Regulatory T cells-centered regulatory networks of skeletal muscle inflammation and regeneration
As the understanding of skeletal muscle inflammation is increasingly clarified, the role of Treg cells in the treatment of skeletal muscle diseases...
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Synergistic effect of umbilical cord extracellular vesicles and rhBMP-2 to enhance the regeneration of a metaphyseal femoral defect in osteoporotic rats
BackgroundThe aim of this study was to evaluate potential synergistic effects of a single, local application of human umbilical cord MSC-derived sEVs...
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Reconstructing the pulmonary niche with stem cells: a lung story
The global burden of pulmonary disease highlights an overwhelming need in improving our understanding of lung development, disease, and treatment. It...
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Protection of adipose-derived mesenchymal stromal cells during acute lung injury requires autophagy maintained by mTOR
Previous studies suggest that mesenchymal stem cells may represent a promising cellular therapy for acute lung injury (ALI); however, the underlying...
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Microbiome in Inflammatory Lung Diseases: Challenges and Future Prospects
The human microbiome is broadly recognized to have a crucial role in various bodily mechanisms that impact immunological homeostasis, inflammation,...
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Redressing the interactions between stem cells and immune system in tissue regeneration
Skeletal muscle has an extraordinary regenerative capacity reflecting the rapid activation and effective differentiation of muscle stem cells...
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Multifaceted Role of Induced Pluripotent Stem Cells in Preclinical Cardiac Regeneration Research
The increasing rate of cardiovascular disease (CVD) worldwide contributes to a worsening quality of life in surviving patients and a socioeconomic...
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ARHGEF3 regulates the stability of ACLY to promote the proliferation of lung cancer
Rho GTPases play an essential role in many cellular processes, including cell cycle progress, cell motility, invasion, migration, and transformation....
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Delineating the twin role of autophagy in lung cancer
Autophagy represents an intracellular defense mechanism equipped within each eukaryotic cells to enable them to cope with variety of physical,...
