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Fly neurons in culture: a model for neural development and pathology
Primary neural cultures from the fruit fly, Drosophila melanogaster , enable a high-resolution glance into cellular processes and neuronal...
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The role of transcription-independent damage signals in the initiation of epithelial wound healing
Wound healing is an essential biological process that comprises sequential steps aimed at restoring the architecture and function of damaged cells...
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Characteristics of Symplasmic Transport
Symplasmic transport is possible in organisms of plants, fungi, and even in animals and some prokaryotes, where cell-to-cell protoplasmic junctions... -
Evolution of cell-to-cell communication and the structural brain organization
The review considers key issues of historical development of the nervous system, including evolution of the brain intercellular contacts and...
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The chemopreventive role of dietary phytochemicals through gap junctional intercellular communication
Dietary phytochemicals offer protection from oxidative damages and lower the risks of chronic diseases, by complementary and overlap** action...
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Deep sequencing-based transcriptome analysis of Plutella xylostella larvae parasitized by Diadegma semiclausum
BackgroundParasitoid insects manipulate their hosts' physiology by injecting various factors into their host upon parasitization. Transcriptomic...
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Fosmid library end sequencing reveals a rarely known genome structure of marine shrimp Penaeus monodon
BackgroundThe black tiger shrimp ( Penaeus monodon ) is one of the most important aquaculture species in the world, representing the crustacean...
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Patterns of dye coupling involving serotonergic neurons provide insights into the cellular organization of a central complex lineage of the embryonic grasshopper Schistocerca gregaria
All eight neuroblasts from the pars intercerebralis of one protocerebral hemisphere whose progeny contribute fibers to the central complex in the...
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Gap junctions in the ovary of Drosophila melanogaster: localization of innexins 1, 2, 3 and 4 and evidence for intercellular communication via innexin-2 containing channels
BackgroundIn the Drosophila ovary, germ-line and soma cells are interconnected via gap junctions. The main gap-junction proteins in invertebrates...
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GExplore: a web server for integrated queries of protein domains, gene expression and mutant phenotypes
BackgroundThe majority of the genes even in well-studied multi-cellular model organisms have not been functionally characterized yet. Mining the...
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Contacts of the endoplasmic reticulum membrane with plasmalemma in plant cells
It is shown by electron microscopy that, in maize root cells, there is close contact between the membrane of the endoplasmic reticulum and the...
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The Biology of Circulating Nucleic Acids in Plasma and Serum (CNAPS)
Although nucleic acids have been known to circulate in the blood since 1948, their biology has been studied only since the 1960s. This chapter... -
Pannexins or Connexins?
Pannexins are a family of three vertebrate proteins that have moderate sequence homology with the innexin proteins, which compose gap junction... -
Stromules: Origin, structure and functions in a plant cell
The review presents a critical analysis of experimental achievements concerning structure and peculiarities of stromules over the last years....
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Two forms of long-term depression in a polysynaptic pathway in the leech CNS: one NMDA receptor-dependent and the other cannabinoid-dependent
Although long-term depression (LTD) is a well-studied form of synaptic plasticity, it is clear that multiple cellular mechanisms are involved in its...
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Connexins: a myriad of functions extending beyond assembly of gap junction channels
Connexins constitute a large family of trans-membrane proteins that allow intercellular communication and the transfer of ions and small signaling...
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The Family of Connexin Genes
The connexin genes code for a family of proteins that form intercellular gap junction channels. There are 21 connexin genes in the human genome and... -
Electrical Signaling with Neuronal Gap Junctions
Neuronal gap junctions — electrical synapses — are ubiquitous across species and brain regions. Electrical synapses typically mediate rapid,... -
Connexin-related signaling in cell death: to live or let die?
Evidence is accumulating that some forms of cell death, like apoptosis, are not only governed by the complex interplay between extracellular and...
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Imaging dynamic cell-cell junctional coupling in vivo using Trojan-LAMP
To study the physiological regulation and function of cell-cell gap junction communication in vivo , we developed a bioconjugate of caged dye, named...