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The model diatom Phaeodactylum tricornutum provides insights into the diversity and function of microeukaryotic DNA methyltransferases
Cytosine methylation is an important epigenetic mark involved in the transcriptional control of transposable elements in mammals, plants and fungi....
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A dynamic intron retention program regulates the expression of several hundred genes during pollen meiosis
Key message Intron retention is a stage-specific mechanism of functional attenuation of a subset of co-regulated, functionally related genes during...
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Lineage-specific energy and carbon metabolism of sponge symbionts and contributions to the host carbon pool
Marine sponges host a wide diversity of microorganisms, which have versatile modes of carbon and energy metabolism. In this study we describe the...
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Ancient homomorphy of molluscan sex chromosomes sustained by reversible sex-biased genes and sex determiner translocation
Contrary to classic theory prediction, sex-chromosome homomorphy is prevalent in the animal kingdom but it is unclear how ancient homomorphic sex...
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RNA landscape of the emerging cancer-associated microbe Fusobacterium nucleatum
Fusobacterium nucleatum , long known as a constituent of the oral microflora, has recently garnered renewed attention for its association with several...
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The carrot monoterpene synthase gene cluster on chromosome 4 harbours genes encoding flavour-associated sabinene synthases
In plants, low molecular weight terpenes produced by terpene synthases (TPS) contribute to multiple ecologically and economically important traits....
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VARUS: sampling complementary RNA reads from the sequence read archive
BackgroundVast amounts of next generation sequencing RNA data has been deposited in archives, accompanying very diverse original studies. The data is...
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Bookend: precise transcript reconstruction with end-guided assembly
We developed Bookend, a package for transcript assembly that incorporates data from different RNA-seq techniques, with a focus on identifying and...
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AtHsp101 research sets course of action for the genetic improvement of crops against heat stress
Caseinolytic protease (Clp)/Hsp100 proteins are members of the AAA+ (ATPase associated with a variety of cellular activities) family of proteins...
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The mitochondrial genomes of Tortricidae: nucleotide composition, gene variation and phylogenetic performance
BackgroundMitochondrial genomes (mitogenomes) have greatly improved our understanding of the backbone phylogeny of Lepidoptera, but few studies on...
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Comprehensive Analysis of Long Non-coding RNA-Associated Competing Endogenous RNA Network in Duchenne Muscular Dystrophy
Duchenne muscular dystrophy (DMD) is one of the most severe neuromuscular disorders. Long non-coding RNAs (lncRNAs) are a group of non-coding...
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De novo RNA sequencing for identification of growth-related genes in Silurus lanzhouensis muscle tissues
To obtain transcriptomic insights into the growth regulation traits of Silurus lanzhouensis , this study employed de novo RNA sequencing to analyze...
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Computational discovery and annotation of conserved small open reading frames in fungal genomes
BackgroundSmall open reading frames (smORF/sORFs) that encode short protein sequences are often overlooked during the standard gene prediction...
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PacBio single molecule long-read sequencing provides insight into the complexity and diversity of the Pinctada fucata martensii transcriptome
BackgroundThe pearl oyster Pinctada fucata martensii is an economically valuable shellfish for seawater pearl production, and production of pearls...
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Re-examination of two diatom reference genomes using long-read sequencing
BackgroundThe marine diatoms Thalassiosira pseudonana and Phaeodactylum tricornutum are valuable model organisms for exploring the evolution,...
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LncRNA RAD51-AS1 Regulates Human Bone Marrow Mesenchymal Stem Cells via Interaction with YBX1 to Ameliorate Osteoporosis
Long noncoding RNA (lncRNA) is a new key regulatory molecule in the occurrence of osteoporosis, but its research is still in the primary stage. In...
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Prediction of a conserved pheromone receptor lineage from antennal transcriptomes of the pine sawyer genus Monochamus (Coleoptera: Cerambycidae)
Longhorned beetles (Cerambycidae) are a diverse family of wood-boring insects, many species of which produce volatile pheromones to attract mates...
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RNA-Seq Data Analysis in Galaxy
A complete RNA-Seq analysis involves the use of several different tools, with substantial software and computational requirements. The Galaxy... -
Seasonal plasticity and diel stability of H3K27me3 in natural fluctuating environments
Diel and seasonal oscillations are two major environmental changes in nature. While organisms cope with the former by the well-characterized...
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A Novel IFITM5 Variant Associated with Phenotype of Osteoporosis with Calvarial Doughnut Lesions: A Case Report
Osteogenesis imperfecta (OI) and other decreased bone density disorders comprise a heterogeneous group of heritable diseases with skeletal fragility....