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Showing 81-100 of 336 results
  1. The model diatom Phaeodactylum tricornutum provides insights into the diversity and function of microeukaryotic DNA methyltransferases

    Cytosine methylation is an important epigenetic mark involved in the transcriptional control of transposable elements in mammals, plants and fungi....

    Antoine Hoguin, Feng Yang, ... Leila Tirichine in Communications Biology
    Article Open access 09 March 2023
  2. A dynamic intron retention program regulates the expression of several hundred genes during pollen meiosis

    Key message

    Intron retention is a stage-specific mechanism of functional attenuation of a subset of co-regulated, functionally related genes during...

    Agnieszka A. Golicz, Annapurna D. Allu, ... Prem L. Bhalla in Plant Reproduction
    Article 21 May 2021
  3. Lineage-specific energy and carbon metabolism of sponge symbionts and contributions to the host carbon pool

    Marine sponges host a wide diversity of microorganisms, which have versatile modes of carbon and energy metabolism. In this study we describe the...

    I. Burgsdorf, S. Sizikov, ... L. Steindler in The ISME Journal
    Article Open access 07 December 2021
  4. Ancient homomorphy of molluscan sex chromosomes sustained by reversible sex-biased genes and sex determiner translocation

    Contrary to classic theory prediction, sex-chromosome homomorphy is prevalent in the animal kingdom but it is unclear how ancient homomorphic sex...

    Wentao Han, Liangjie Liu, ... Shi Wang in Nature Ecology & Evolution
    Article 24 October 2022
  5. RNA landscape of the emerging cancer-associated microbe Fusobacterium nucleatum

    Fusobacterium nucleatum , long known as a constituent of the oral microflora, has recently garnered renewed attention for its association with several...

    Falk Ponath, Caroline Tawk, ... Jörg Vogel in Nature Microbiology
    Article 08 July 2021
  6. The carrot monoterpene synthase gene cluster on chromosome 4 harbours genes encoding flavour-associated sabinene synthases

    In plants, low molecular weight terpenes produced by terpene synthases (TPS) contribute to multiple ecologically and economically important traits....

    Sven Reichardt, Holger Budahn, ... Lilya Kopertekh in Horticulture Research
    Article Open access 01 December 2020
  7. VARUS: sampling complementary RNA reads from the sequence read archive

    Background

    Vast amounts of next generation sequencing RNA data has been deposited in archives, accompanying very diverse original studies. The data is...

    Mario Stanke, Willy Bruhn, ... Katharina J. Hoff in BMC Bioinformatics
    Article Open access 08 November 2019
  8. Bookend: precise transcript reconstruction with end-guided assembly

    We developed Bookend, a package for transcript assembly that incorporates data from different RNA-seq techniques, with a focus on identifying and...

    Michael A. Schon, Stefan Lutzmayer, ... Michael D. Nodine in Genome Biology
    Article Open access 29 June 2022
  9. AtHsp101 research sets course of action for the genetic improvement of crops against heat stress

    Caseinolytic protease (Clp)/Hsp100 proteins are members of the AAA+ (ATPase associated with a variety of cellular activities) family of proteins...

    Ritesh Kumar, Lisha Khungar, ... Anil Grover in Journal of Plant Biochemistry and Biotechnology
    Article 23 October 2020
  10. The mitochondrial genomes of Tortricidae: nucleotide composition, gene variation and phylogenetic performance

    Background

    Mitochondrial genomes (mitogenomes) have greatly improved our understanding of the backbone phylogeny of Lepidoptera, but few studies on...

    Mingsheng Yang, Junhao Li, ... Lili Li in BMC Genomics
    Article Open access 21 October 2021
  11. Comprehensive Analysis of Long Non-coding RNA-Associated Competing Endogenous RNA Network in Duchenne Muscular Dystrophy

    Duchenne muscular dystrophy (DMD) is one of the most severe neuromuscular disorders. Long non-coding RNAs (lncRNAs) are a group of non-coding...

    **aoxue Xu, Yuehan Hao, ... Zhiyi He in Interdisciplinary Sciences: Computational Life Sciences
    Article 02 September 2020
  12. De novo RNA sequencing for identification of growth-related genes in Silurus lanzhouensis muscle tissues

    To obtain transcriptomic insights into the growth regulation traits of Silurus lanzhouensis , this study employed de novo RNA sequencing to analyze...

    Wei **ao, Zong-Qiang Lian, ... Qing-Yun Sai in Fisheries Science
    Article 11 August 2022
  13. Computational discovery and annotation of conserved small open reading frames in fungal genomes

    Background

    Small open reading frames (smORF/sORFs) that encode short protein sequences are often overlooked during the standard gene prediction...

    Shuhaila Mat-Sharani, Mohd Firdaus-Raih in BMC Bioinformatics
    Article Open access 04 February 2019
  14. PacBio single molecule long-read sequencing provides insight into the complexity and diversity of the Pinctada fucata martensii transcriptome

    Background

    The pearl oyster Pinctada fucata martensii is an economically valuable shellfish for seawater pearl production, and production of pearls...

    Hua Zhang, Hanzhi Xu, ... Maoxian He in BMC Genomics
    Article Open access 13 July 2020
  15. Re-examination of two diatom reference genomes using long-read sequencing

    Background

    The marine diatoms Thalassiosira pseudonana and Phaeodactylum tricornutum are valuable model organisms for exploring the evolution,...

    Gina V. Filloramo, Bruce A. Curtis, ... John M. Archibald in BMC Genomics
    Article Open access 24 May 2021
  16. LncRNA RAD51-AS1 Regulates Human Bone Marrow Mesenchymal Stem Cells via Interaction with YBX1 to Ameliorate Osteoporosis

    Long noncoding RNA (lncRNA) is a new key regulatory molecule in the occurrence of osteoporosis, but its research is still in the primary stage. In...

    Beichen Li, **g Wang, ... Qiang Sun in Stem Cell Reviews and Reports
    Article 21 June 2022
  17. Prediction of a conserved pheromone receptor lineage from antennal transcriptomes of the pine sawyer genus Monochamus (Coleoptera: Cerambycidae)

    Longhorned beetles (Cerambycidae) are a diverse family of wood-boring insects, many species of which produce volatile pheromones to attract mates...

    Robert F. Mitchell, Daniel Doucet, ... Jeremy D. Allison in Journal of Comparative Physiology A
    Article 15 October 2022
  18. RNA-Seq Data Analysis in Galaxy

    A complete RNA-Seq analysis involves the use of several different tools, with substantial software and computational requirements. The Galaxy...
    Bérénice Batut, Marius van den Beek, ... Nicola Soranzo in RNA Bioinformatics
    Protocol Open access 2021
  19. Seasonal plasticity and diel stability of H3K27me3 in natural fluctuating environments

    Diel and seasonal oscillations are two major environmental changes in nature. While organisms cope with the former by the well-characterized...

    Haruki Nishio, Atsushi J. Nagano, ... Hiroshi Kudoh in Nature Plants
    Article 31 August 2020
  20. A Novel IFITM5 Variant Associated with Phenotype of Osteoporosis with Calvarial Doughnut Lesions: A Case Report

    Osteogenesis imperfecta (OI) and other decreased bone density disorders comprise a heterogeneous group of heritable diseases with skeletal fragility....

    R. E. Mäkitie, M. Pekkinen, ... O. Mäkitie in Calcified Tissue International
    Article Open access 22 June 2021
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