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MSC Studies in Large-Animal Models
Mesenchymal stromal cells found within bone marrow, fat, and other tissues are a population of cells with the potential to mediate therapeutic... -
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Relationship of Oxidative Stress with Cardiovascular Disease
More women die from complications related to cardiovascular disease (CVD) each year than men, yet dysfunction of the heart and blood vessels is still... -
Dynamics of human cardiovascular responses in different periods of long-term exposure to weightlessness
The purpose of this work was to determine the dynamics of changes in the state of the human cardiovascular system at rest and upon exposure to lower...
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PTP1B in Obesity-Related Cardiovascular Function
Protein tyrosine phosphatase 1B (PTP1B), a molecular brake on leptin and insulin signaling pathways, is an important regulator of metabolic... -
Non-steroid anti-inflammatory drugs, prostaglandins, and cancer
Fatty acids are involved in multiple pathways and play a pivotal role in health. Eicosanoids, derived from arachidonic acid, have received extensive...
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Perinatal taurine exposure affects adult arterial pressure control
Taurine is an abundant, free amino acid found in mammalian cells that contributes to many physiologic functions from that of a simple cell osmolyte...
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Cardiovascular Circuits and Digestive Function of Intermittent-Feeding Sauropsids
Turtles, squamates, and crocodiles show remarkable morphological and physiological plasticity of their gastrointestinal tract in response to feeding.... -
Physiological Responses to Starvation in Snakes: Low Energy Specialists
Many types of snakes are capable of surviving over a year of complete starvation. The physiological effects of food limitation on snakes can be... -
Western-style diet modulates contractile responses to phenylephrine differently in mesenteric arteries from senescence-accelerated prone (SAMP8) and resistant (SAMR1) mice
The influence of two known cardiovascular risk factors, aging and consumption of a high-fat diet, on vascular mesenteric artery reactivity was...
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Aging enhances contraction to thromboxane A2 in aorta from female senescence-accelerated mice
The time-course for aging-associated effects on vascular reactivity to U46619, a stable analogue of thromboxane A 2 (TXA 2 ), was studied in aorta from...
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Avian metabolism: its control and evolution
This review discussed metabolism in poultry and wild birds with an emphasis on what remains to be elucidated. Circulating concentrations of glucose...
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Developmental changes in mesenteric artery reactivity in embryonic and newly hatched chicks
At birth, the intestine becomes the sole site for nutrient absorption requiring a dramatic increase in blood flow. The vascular changes accompanying...
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The Renin Angiotensin System
The renin angiotensin system (RAS) is a hormonal cascade that is thought to act as a master controller of blood pressure and fluid balance within the... -
Crustacean neuropeptides
Crustaceans have long been used for peptide research. For example, the process of neurosecretion was first formally demonstrated in the crustacean...
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Some Molecular Aspects in the Biology of Respiration
The development of an embryo is instructed by the vast information encoded in the genome. Transactions of information contained in the DNA direct the... -
Agonist of serotonin 5HT1A-receptors 8-OH-DPAT increases the force of contraction of rat aorta and mesenteric artery in the presence of endothelin-1 or vasopressin and causes relaxation of the vessels preconstricted with noradrenaline
Agonist 5HT1A serotonin receptors 8-OH-DPAT at 70–80% in rats relax the isolated aorta and mesenteric artery, precollapsed with noradrenaline. An...
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Modulation of stomatogastric rhythms
Neuromodulation by peptides and amines is a primary source of plasticity in the nervous system as it adapts the animal to an ever-changing...