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Rhythmicity of neuronal oscillations delineates their cortical and spectral architecture
Neuronal oscillations are commonly analyzed with power spectral methods that quantify signal amplitude, but not rhythmicity or ‘oscillatoriness’ per...
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Neurological Effects of Cannabis
Cannabis products and Cannabis use are inherently variable. Given the difficulty in standardizing Cannabis products and Cannabis use patterns,...
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Intracranial direct electrical map** reveals the functional architecture of the human basal ganglia
The basal ganglia play a key role in integrating a variety of human behaviors through the cortico–basal ganglia–thalamo–cortical loops. Accordingly,...
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Assessing the arrhythmogenic propensity of fibrotic substrate using digital twins to inform a mechanisms-based atrial fibrillation ablation strategy
Atrial fibrillation (AF), the most common heart rhythm disorder, may cause stroke and heart failure. For patients with persistent AF with fibrosis...
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Visual System of the Only Nocturnal Anthropoid, Aotus: The Owl Monkey
Diurnal haplorhines exhibit derived traits for high-acuity photopic vision, unique across mammals, and many other vertebrates. Yet, sometime in the...
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First report of whole genome sequence of septicemic Pasteurella multocida serovar B:2 ‘Soron’ strain isolated from swine
Pig pasteurellosis, caused by Pasteurella multocida , is an acute infection that also has economic implications for pig farmers. We report the...
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Multivariate genome-wide analysis of education, socioeconomic status and brain phenome
Socioeconomic status (SES) and education (EDU) are phenotypically associated with psychiatric disorders and behaviours. It remains unclear how these...
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Psychotropic Effects of Cannabis
Brain development is a complex phenomenon from fetal life to adolescence. During this period, the brain’s maturation proceeds through a series of...
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Electrotrawling can improve the sustainability of the bottom trawl fishery for sole: a review of the evidence
Between 2009 and 2021 almost the complete beam trawl fleet of the Netherlands switched from conventional beam trawls (BT) to pulse trawls (PT) using...
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Cross species review of the physiological role of d-serine in translationally relevant behaviors
Bridging the gap between preclinical models of neurological and psychiatric disorders with their human manifestations is necessary to understand...
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DRDs and Brain-Derived Neurotrophic Factor Share a Common Therapeutic Ground: A Novel Bioinformatic Approach Sheds New Light Toward Pharmacological Treatment of Cognitive and Behavioral Disorders
Cognitive and behavioral disorders are subgroups of mental health disorders. Both cognitive and behavioral disorders can occur in people of different...
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Removal of a partial genomic duplication restores synaptic transmission and behavior in the MyosinVA mutant mouse Flailer
BackgroundCopy number variations, and particularly duplications of genomic regions, have been strongly associated with various neurodegenerative...
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DNA Instability in Neurons: Lifespan Clock and Driver of Evolution
AbstractIn the last ten years, the discovery of neuronal DNA postmitotic instability has changed the theoretical landscape in neuroscience and, more...
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Genomewide alteration of histone H3K4 methylation underlies genetic vulnerability to psychopathology
Dysregulated histone methylation has emerged as a recurring theme in multiple neuropsychiatric disorders. However, it is yet unclear whether the...
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5-HT2AR and NMDAR psychedelics induce similar hyper-synchronous states in the rat cognitive-limbic cortex-basal ganglia system
The profound changes in perception and cognition induced by psychedelic drugs are thought to act on several levels, including increased glutamatergic...
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Biology and Management of Spot Blotch Pathogen Bipolaris sorokiniana of Wheat
Bipolaris sorokiniana (Teleomorph: Cochliobolus sativus), causal agent of spot blotch of wheat, emerges as a serious concern for yield losses to...
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Thermal-plex: fluidic-free, rapid sequential multiplexed imaging with DNA-encoded thermal channels
Multiplexed fluorescence imaging is typically limited to three- to five-plex on standard setups. Sequential imaging methods based on iterative...
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A microfluidics-based stem cell model of early post-implantation human development
Early post-implantation human embryonic development has been challenging to study due to both technical limitations and ethical restrictions. Proper...
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Human-specific evolutionary markers linked to foetal neurodevelopment modulate brain surface area in schizophrenia
Schizophrenia may represent a trade-off in the evolution of human-specific ontogenetic mechanisms that guide neurodevelopment. Human Accelerated...
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Multiocular organoids from human induced pluripotent stem cells displayed retinal, corneal, and retinal pigment epithelium lineages
BackgroundRecently, great efforts have been made to design protocols for obtaining ocular cells from human stem cells to model diseases or for...
