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Temporal and spatial expression of Drosophila Neurexin during the life cycle visualized using a DNRX-Gal4/UAS-reporter
Drosophila neurexin (DNRX) plays a critical role in proper architecture development and synaptic function in vivo . However, the temporal and spatial...
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Tandem duplications of receptor-like kinase genes reshaped the homologous chromosome 1 regions in Oryza sativa ssp. indica and japonica and their possible ancestral genomes
Plant receptor-like kinase ( Rlk ) genes form a large family, each encoding a protein with a signal motif, a single transmembrane region, and a...
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Annotation of Alternatively Spliced Proteins and Transcripts with Protein-Folding Algorithms and Isoform-Level Functional Networks
Tens of thousands of splice isoforms of proteins have been catalogued as predicted sequences from transcripts in humans and other species. Relatively...
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Drosophila anti-nematode and antibacterial immune regulators revealed by RNA-Seq
BackgroundDrosophila melanogaster activates a variety of immune responses against microbial infections. However, information on the Drosophila ...
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Autophagy-independent function of Atg1 for apoptosis-induced compensatory proliferation
BackgroundATG1 belongs to the Uncoordinated-51-like kinase protein family. Members of this family are best characterized for roles in macroautophagy...
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Roles of cofactors and chromatin accessibility in Hox protein target specificity
BackgroundThe regulation of specific target genes by transcription factors is central to our understanding of gene network control in developmental...
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Representation of anatomy in online atlases and databases: a survey and collection of patterns for interface design
BackgroundA large number of online atlases and databases have been developed to mange the rapidly growing amount of data describing embryogenesis. As...
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Comparative Genomics of Transcription Factor Binding in Drosophila
While the number of genome-wide, in vivo transcription factor binding datasets is growing, yielding greater insight into the role of regulatory DNA...
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Tutorial: ein Überblick zu wichtigen Datenbanken und Programmen
Die Tutorials sind dafür gedacht, Sie im Überblick einmal durch wichtige Analyseschritte und zugehörige Softwares zu führen, die im...
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The Brachypodium distachyon Reference Genome
Grasses provide the bulk of human calories but improvement in grass yields is hindered by the characteristically large and complex genomes of these...
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Strategies for gene disruption in Drosophila
Drosophila melanogaster has been a classic model organism for the studies of genetics. More than 15,000 Drosophila genes have been annotated since...
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Functional characterization of a defense-related class-III chitinase promoter from Lupinus albus, active in legume and monocot tissues
A class-III chitinase promoter was isolated from Lupinus albus. The region 5′ to the coding sequence of the IF3 gene was amplified by gene walking...
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Molecular cloning and expression analysis of the mevalonate diphosphate decarboxylase gene from the latexof Hevea brasiliensis
Mevalonate diphosphate decarboxylase (MVD) catalyzes the conversion of mevalonate diphosphate to isopentenyl diphosphate (IPP), a monomer of a large...
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Isolation and Comparative Genomic Analysis of T1-Like Shigella Bacteriophage pSf-2
The increasing prevalence of antibiotic-resistant Shigella sp. emphasizes that alternatives to conventional antibiotics are needed. Siphoviridae ...
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Amnioserosa cell constriction but not epidermal actin cable tension autonomously drives dorsal closure
Tissue morphogenesis requires coordination of multiple force-producing components. During dorsal closure in fly embryogenesis, an epidermis opening...
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Structureomics in Systems-Based Drug Discovery
Selection of the appropriate drug target is crucial and furthermore its association with small molecule binding partners is the subject of extensive...
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The histone demethylase dKDM5/LID interacts with the SIN3 histone deacetylase complex and shares functional similarities with SIN3
BackgroundRegulation of gene expression by histone-modifying enzymes is essential to control cell fate decisions and developmental processes. Two...
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Deletion of
Drosophila Nopp140 induces subcellular ribosomopathiesThe nucleolar and Cajal body phosphoprotein of 140 kDa (Nopp140) is considered a ribosome assembly factor, but its precise functions remain unknown....
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Insect Regulatory Genomics
Insects are the most diverse and ecologically important group of animals in the animal kingdom, with more than a million species described to date....