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Design of Epidemiologic Studies
Experimental studies have active exposure assigned by the researchers. An important component to this active assignment is randomization.... -
Map** Major Disease Resistance Genes in Soybean by Genome-Wide Association Studies
Soybean is one of the most valuable agricultural crops in the world. Besides, this legume is constantly attacked by a wide range of pathogens (fungi,... -
Multiple phenotype association tests based on sliced inverse regression
BackgroundJoint analysis of multiple phenotypes in studies of biological systems such as Genome-Wide Association Studies is critical to revealing the...
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Studies on the epibiotic association between rotifer Brachionus rubens and cladocerans from water bodies of Jammu and Kashmir, India
The epibiotic relationship was studied between the rotifer Brachionus rubens and five cladocerans ( Daphnia carinata, Moina micrura, Simocephalus...
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Genome-wide association studies of yield-related traits in high-latitude japonica rice
BackgroundHeilongjiang Province is a high-quality japonica rice cultivation area in China. One in ten bowls of Chinese rice is produced here....
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Meta-analysis of genome-wide association studies identifies ancestry-specific associations underlying circulating total tau levels
Circulating total-tau levels can be used as an endophenotype to identify genetic risk factors for tauopathies and related neurological disorders....
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Genome-wide association studies: assessing trait characteristics in model and crop plants
GWAS involves testing genetic variants across the genomes of many individuals of a population to identify genotype–phenotype association. It was...
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Genetic dissection of maize (Zea maysL.) trace element traits using genome-wide association studies
Maize ( Zea mays L.) is an important food and feed crop worldwide and serves as a a vital source of biological trace elements, which are important...
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High-Throughput Association Map** in Brassica napus L.: Methods and Applications
Oil seed rape (Braasica napus L.) is ranked second among oil seed crops cultivated globally for edible oil for human, and seed cake for animal... -
Association Between Methylenetetrahydrofoate Reductase Gene C677T Polymorphism and Susceptibility to Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is the most common form of endocrinopathy of women. Several studies have investigated the association of...
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sPLINK: a hybrid federated tool as a robust alternative to meta-analysis in genome-wide association studies
Meta-analysis has been established as an effective approach to combining summary statistics of several genome-wide association studies (GWAS)....
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Hybrid performance evaluation and genome-wide association analysis of root system architecture in a maize association population
Key MessageThe genetic architecture of RSA traits was dissected by GWAS and coexpression networks analysis in a maize association population.
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Genome-wide association studies for immunoglobulin concentrations in colostrum and serum in Chinese Holstein
BackgroundThe early death and health problems of calves caused substantial economic losses in the dairy industry. As the immune system of neonates...
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The statistical power of genome-wide association studies for threshold traits with different frequencies of causal variants
This study aimed to investigate the effects of incidence rate, heritability, and polygenic variance on the statistical power of genome-wide...
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Dissecting polygenic signals from genome-wide association studies on human behaviour
Genome-wide association studies on human behavioural traits are producing large amounts of polygenic signals with significant predictive power and...
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Identification of quantitative trait loci for related traits of stalk lodging resistance using genome-wide association studies in maize (Zea mays L.)
BackgroundStalk lodging is one of the main factors affecting maize ( Zea mays L.) yield and limiting mechanized harvesting. Develo** maize...
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Genome-wide association studies reveal novel loci for grain size in two-rowed barley (Hordeum vulgare L.)
Key messageSNP-based and InDel-based GWAS on multi-environment data identified genomic regions associated with barley grain size.
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Multi-locus genome-wide association studies for five yield-related traits in rice
BackgroundImproving the overall production of rice with high quality is a major target of breeders. Mining potential yield-related loci have been...
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Genome-Wide Association Study Statistical Models: A Review
Statistical models are at the core of the genome-wide association study (GWAS). In this chapter, we provide an overview of single- and multilocus... -
Molecular transformations and self-association in anthocyanin pigment patterns
Spatial patterns of red, purple, and blue colors due to plant pigments called anthocyanins appear in a wide variety of flower petals. Activator and...