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Highly aneuploid non-small cell lung cancer shows enhanced responsiveness to concurrent radiation and immune checkpoint blockade
Over 500 clinical trials are investigating combination radiotherapy and immune checkpoint blockade (ICB) as cancer treatments; however, the majority...
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Eleutheroside E supplementation prevents radiation-induced cognitive impairment and activates PKA signaling via gut microbiota
Radiation affects not only cognitive function but also gut microbiota. Eleutheroside E (EE), a principal active compound of Acanthopanax senticosus,...
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Influence of Low-Intensive He-Ne Laser Radiation on the Composition and Content of Phospholipids and Sterols in the Callus Tissues of Wheat Тriticum aestivum L.
AbstractThe effect of He-Ne laser radiation on the composition and content of cell membrane components, namely phospholipids (PL) and sterols, in...
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Microgravity and space radiation inhibit autophagy in human capillary endothelial cells, through either opposite or synergistic effects on specific molecular pathways
Microgravity and space radiation (SR) are two highly influential factors affecting humans in space flight (SF). Many health problems reported by...
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Adaptive Properties of Arthrobacter agilis Strain wb28 Isolated from Wheat Bran
Abstract —The article presents the results of a study of some adaptive properties of a bacterial isolate from wheat bran, identified by the 16S rRNA...
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Global dispersal and adaptive evolution of domestic cattle: a genomic perspective
Domestic cattle have spread across the globe and inhabit variable and unpredictable environments. They have been exposed to a plethora of selective...
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Light (High Light/UV Radiation) Modulates Adaptation Mechanisms and Secondary Metabolite Production in Medicinal Plants
Traditional medicines have long been making the use of plants that produce the secondary metabolites of therapeutic importance. However, in order to...
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Low-dose radiation exaggerates HFD-induced metabolic dysfunction by gut microbiota through PA-PYCR1 axis
Co-exposure of High-fat-diet (HFD) behavior and environmental low-dose radiation (LDR) is common among majority occupational workers, but the...
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Adaptive strategy in control of ectoparasitic infection in Eurasian tree sparrow
BackgroundSelection pressure due to parasitic infestation puts adverse effects on birds’ fitness concerning survival and reproductive success. The...
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Longitudinal multi-omic changes in the transcriptome and proteome of peripheral blood cells after a 4 Gy total body radiation dose to Rhesus macaques
BackgroundNon-human primates, such as Rhesus macaques, are a powerful model for studies of the cellular and physiological effects of radiation,...
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Quaternary history and radiation of Salvelinus fish in the ancient Arctic Lake El’gygytgyn
El’gygytgyn is the only ancient lake in the Arctic that avoided continental-scale glaciations. This lake is located on an arid mountain plateau, far...
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Adaptive Phenotypic Divergence in Fishes of Japan: Potential Model Systems for Ecological and Evolutionary Genomics
Recent progress in ecological and evolutionary genomicsEcological and evolutionary genomics has provided insight into why and how so many phenotypes...
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Profiling ATM regulated genes in Drosophila at physiological condition and after ionizing radiation
BackgroundATM (ataxia-telangiectasia mutated) protein kinase is highly conserved in metazoan, and plays a critical role at DNA damage response,...
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Genetic diversity and gene expression diversity shape the adaptive pattern of the aquatic plant Batrachium bungei along an altitudinal gradient on the Qinghai–Tibet plateau
It is an intriguing issue of evolutionary biology how genetic diversity and gene expression diversity shape the adaptive patterns. Comparative...
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Decomplicating and identifying species in the radiation of the Antarctic fish genus Pogonophryne (Artedidraconidae)
The 27 species of the genus Pogonophryne are a distinctive component of the radiation of cryonotothenioid fishes and commonly encountered during...
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Mesenchymal Stem Cell-Derived Exosomes are Effective for Radiation Enteritis and Essential for the Proliferation and Differentiation of Lgr5+ Intestinal Epithelial Stem Cells by Regulating Mir-195/Akt/β-Catenin Pathway
Background:Radiation enteritis (RE) is a common complication of abdominal or pelvic radiotherapy, which when severe, could be life-threatening....
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Genomic variation from an extinct species is retained in the extant radiation following speciation reversal
Ecosystem degradation and biodiversity loss are major global challenges. When reproductive isolation between species is contingent on the interaction...
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Genomic Insights on Global Journeys of Adaptive Wheat Genes that Brought Us to Modern Wheat
Since its first cultivation, hexaploid wheat has evolved, allowing for its widespread cultivation and contributing to global food security. The...
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Solutions: how adaptive changes in cellular fluids enable marine life to cope with abiotic stressors
The seas confront organisms with a suite of abiotic stressors that pose challenges for physiological activity. Variations in temperature, hydrostatic...
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Metallo-adaptive response: a unique survival strategy of plants under genotoxic stress
The sedentary nature of a plant’s lifestyle has lead to the evolvement of different strategies to minimise the effects of various genotoxic...
