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Matrix metalloproteinase 9 contributes to gut microbe homeostasis in a model of infectious colitis
BackgroundInflammatory bowel diseases are associated with increased expression of zinc-dependent Matrix Metalloproteinase 9 (MMP-9). A stark...
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Measures of phylogenetic differentiation provide robust and complementary insights into microbial communities
High-throughput sequencing techniques have made large-scale spatial and temporal surveys of microbial communities routine. Gaining insight into...
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Quantitative trait loci in a bacterially induced model of inflammatory bowel disease
Inflammatory bowel diseases (IBDs) are complex disorders caused by a combination of environmental, microbial, and genetic factors. Genome-wide...
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Caspase deficiency alters the murine gut microbiome
Caspases are aspartate-specific cysteine proteases that have an essential role in apoptosis and inflammation, and contribute to the maintenance of...
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Culture-independent methods for studying environmental microorganisms: methods, application, and perspective
Since the application of molecular methods, culture-independent methods (CIMs) have been developed to study microbial communities from various...
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Characterization of Housing-Related Spontaneous Variations of Gut Microbiota and Expression of Toll-Like Receptors 2 and 4 in Rats
Gut microbiota has been suggested as a key component of gut homeostasis, affecting immune responses within the gut. We determined changes in...
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Effects of xylooligosaccharide on growth performance, activities of digestive enzymes, and intestinal microflora of juvenile Pelodiscus sinensis
The effects of xylooligosaccharide (XOS) on growth performance, activities of digestive enzymes, and intestinal microflora of Chinese soft-shelled...
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The Development and Stability of the Genus Bacteriodes from Human Gut Microbiota in HFA Mice Model
Human flora-associated (HFA) mice are frequently applied in studying the ecology and metabolism of human gut microbiota. However, the development and...
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Whole-genome microarray analysis and functional characterization reveal distinct gene expression profiles and patterns in two mouse models of ileal inflammation
BackgroundAlthough a number of intestinal inflammatory conditions pertain to the ileum, whole-genome gene expression analyses in animal models of...
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Recent advances on biological difructose anhydride III production using inulase II from inulin
Difructose anhydride III (DFA III), the smallest cyclic disaccharide, consists of two fructose residues. DFA III is a hydrolysate of inulin and is...
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Spatial organization of intestinal microbiota in the mouse ascending colon
Complex microbial populations are organized in relation to their environment. In the intestine, the inner lining (mucosa) is a potential focal point...
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The ciliate,
Troglodytella abrassarti , contributes to polysaccharide hydrolytic activities in the chimpanzee colonEntodiniomorphid ciliates are intestinal protists inhabiting the colons of African great apes. The participation of intestinal entodiniomorphid...
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Comparative fecal metagenomics unveils unique functional capacity of the swine gut
BackgroundUncovering the taxonomic composition and functional capacity within the swine gut microbial consortia is of great importance to animal...
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The Human Microbiome and Host–Pathogen Interactions
In the past, medical microbiology has largely relied on simplifying assumptions of one-to-one relationships: between a single pathogen and a single...
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Effects of different starch sources on Bacillus spp. in intestinal tract and expression of intestinal development related genes of weanling piglets
The study was conducted to evaluate the effects of different starch sources on Bacillus spp. in intestinal tract and expression of intestinal...
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Effects of apples and specific apple components on the cecal environment of conventional rats: role of apple pectin
BackgroundOur study was part of the large European project ISAFRUIT aiming to reveal the biological explanations for the epidemiologically...
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Metagenomic Applications and the Potential for Understanding Chronic Liver Disease
Liver fibrosis is characterized by an excessive deposition of extracellular matrix proteins that occurs in chronic liver disease of any origin....
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Community analysis of bacteria colonizing intestinal tissue of neonates with necrotizing enterocolitis
BackgroundNecrotizing enterocolitis (NEC) is the most common gastrointestinal emergency in newborn neonates. Bacteria are believed to be important in...
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Impact of training sets on classification of high-throughput bacterial 16s rRNA gene surveys
Taxonomic classification of the thousands–millions of 16S rRNA gene sequences generated in microbiome studies is often achieved using a naïve...
