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On the use of adenovirus dodecahedron as a carrier for glycoconjugate vaccines
Virus-Like Particles (VLPs) have been used as immunogenic molecules in numerous recombinant vaccines. VLPs can also serve as vaccine platform to...
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Bioengineering and Bioprocessing of Virus-Like Particle Vaccines in Escherichia coli
Virus-like particles (VLPs) are macromolecular assemblies of recombinant viral structural proteins. Self-assembling with high precision, the...
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The endocytic recycling compartment serves as a viral factory for hepatitis E virus
Although hepatitis E virus (HEV) is the major leading cause of enterically transmitted viral hepatitis worldwide, many gaps remain in the...
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Comprehensive insight into altered host cell-signaling cascades upon Helicobacter pylori and Epstein–Barr virus infections in cancer
Cancer is characterized by mutagenic events that lead to disrupted cell signaling and cellular functions. It is one of the leading causes of death...
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Antibacterial and anti-corona virus (229E) activity of Nigella sativa oil combined with photodynamic therapy based on methylene blue in wound infection: in vitro and in vivo study
Microbial skin infections, antibiotic resistance, and poor wound healing are major problems, and new treatments are needed. Our study targeted...
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Topical application of dsRNA for plant virus control: a review
RNA interference (RNAi) is a mechanism in which dsRNA is processed by the cell machinery mediating post-transcriptional or transcriptional gene...
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Size variations of mesoporous silica nanoparticle control uptake efficiency and delivery of AC2-derived dsRNA for protection against tomato leaf curl New Delhi virus
Key messageWe report the size dependent uptake of dsRNA loaded MSNPs into the leaves and roots of
Nicotiana benthamiana plants and accessed for their...
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Core promoter mutation of nucleotides A1762T and G1764A of hepatitis B virus increases core promoter transactivation by hepatocyte nuclear factor 1
Hepatitis B virus (HBV) infection highly increases the risk for liver cirrhosis and hepatocellular carcinoma (HCC). The clinical manifestation of HBV...
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Functional analysis revealed the involvement of ZmABCB15 in resistance to rice black-streaked dwarf virus infection
BackgroundMaize rough dwarf disease (MRDD), caused by rice black-streaked dwarf virus (RBSDV) belonging to the Fijivirus genus, seriously threatens...
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Prediction of Virus-Receptor Interactions Based on Similarity and Matrix Completion
Viral infectious diseases are threatening human health and global security by rapid transmission and severe fatalities. The receptor-binding is the...
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Transcriptome analysis of Citrus limon infected with Citrus yellow vein clearing virus
BackgroundCitrus yellow vein clearing virus (CYVCV) is the causative agent of citrus yellow vein clearing disease, and poses a serious threat to the...
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Spray application of a cocktail of dsRNAs reduces infection of chilli leaf curl virus in Nicotiana benthamiana
Chilli leaf curl virus (ChiLCV) is a monopartite begomovirus (family Geminiviridae ) that spreads exclusively through an insect vector, whitefly ( Bemis...
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Detection of low-load Epstein-Barr virus in blood samples by enriched recombinase aided amplification assay
Epstein-Barr virus (EBV), a common human γ-herpesvirus, infects more than 90% of adults worldwide. The purpose of this study was to establish a novel...
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Putative priming effect of Seguieria langsdorffii Moq. leaf extract in Cucurbita pepo L. infected by zucchini yellow mosaic virus
Cucurbita pepo L., an important crop in Brazil, can be infected by zucchini yellow mosaic virus (ZYMV), an aphid-transmitted Potyvirus . To avoid the...
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N6-methyladenosine modification of the Aedes aegypti transcriptome and its alteration upon dengue virus infection in Aag2 cell line
The N 6 -methyladenosine (m 6 A) modification of RNA has been reported to affect viral infections. Studies have confirmed the role of m 6 A in replication...
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Polyamine-metabolizing enzymes are activated to promote the proper assembly of rice stripe mosaic virus in insect vectors
Both viruses and host cells compete for intracellular polyamines for efficient propagation. Currently, how the key polyamine-metabolizing enzymes,...
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Barley yellow dwarf virus-infected wheat plant modulated selection behavior of vector aphids
Evolution of the spread strategies of plant pathogens may be described using the vector manipulation hypothesis (VMH), which posits that pathogens...
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Viral tag and grow: a scalable approach to capture and characterize infectious virus–host pairs
Viral metagenomics (viromics) has reshaped our understanding of DNA viral diversity, ecology, and evolution across Earth’s ecosystems. However,...
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Exploratory study of volatile fatty acids and the rumen-and-gut microbiota of dairy cows in a single farm, with respect to subclinical infection with bovine leukemia virus
BackgroundSubclinical infection with bovine leukemia virus (BLV) in cows can cause economic losses in milk and meat production in many countries, as...
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Fabrication and characterization of CdS nanowires templated in tobacco mosaic virus with improved photocatalytic ability
AbstractUsing a virus as a template to synthesize nanomaterial is a simple, green, and controllable method to acquire unique structure nanoparticles....
