Search
Search Results
-
Versatile generation of precise gene edits in bovines using SEGCPN
BackgroundGene knockout and knock-in have been widely performed in large farm animals based on genome editing systems. However, many types of precise...
-
Development and Vision of CRISPR-Based Technology
Genome editing mediated by these nucleases has been used to rapidly, easily and efficiently modify endogenous genes in a wide variety of biomedically...
-
A Method for Precisely Identifying Modifications to Plant Mitochondrial Genomes by mitoTALENs
The ability to transform plant mitochondrial genomes has many benefits. Although delivery of foreign DNA to mitochondria is presently very difficult,...
-
Genome editing in plants: a tool for precision breeding and functional genomics
Genome or gene editing (GE) involves a repertoire of innovative molecular techniques that make use of sequence-specific nucleases (SSNs), for the...
-
Metabolic Engineering for High-Value Bioactive Compounds from Medicinal Plants
Medicinal plants produce a heterogeneous group of natural metabolic products having distinct compounds conferring adaptive roles like in defense,...
-
Soybean Improvement and the Role of Gene Editing
Soybean is a major agricultural crop that is used for food, feed, and industrial products. However, soybean production is facing several challenges,...
-
Application of CRISPR/Cas system in optimizing nutrients and anti-nutrients content in fruits
From time immemorial, fruits are taken by human as staple food which are rich in nutrients like vitamins, carbohydrates, minerals, dietary fibres and...
-
CRISPR-Cas9 and beyond: what’s next in plant genome engineering
Scientists have developed and deployed successive generations of genome engineering technologies for use in plants, including meganucleases, zinc...
-
Comparison of DNA targeting CRISPR editors in human cells
BackgroundProfiling and comparing the performance of current widely used DNA targeting CRISPR systems provide the basic information for the...
-
CRISPR-Cas9 based molecular breeding in crop plants: a review
Traditional crop breeding techniques are not quickly boosting yields to fulfill the expanding population needs. Long crop lifespans hinder the...
-
CRISPR/Cas tool designs for multiplex genome editing and its applications in develo** biotic and abiotic stress-resistant crop plants
Crop plants are prone to several yield-reducing biotic and abiotic stresses. The crop yield reductions due to these stresses need addressing to...
-
CRISPR/Cas9 mediated genome editing tools and their possible role in disease resistance mechanism
Several phytopathogens have detrimental effects on crop production and productivity potentially threatening global food security. Studying the...
-
Structural and functional analyses of Burkholderia pseudomallei BPSL1038 reveal a Cas-2/VapD nuclease sub-family
Burkholderia pseudomallei is a highly versatile pathogen with ~25% of its genome annotated to encode hypothetical proteins. One such hypothetical...
-
The Application of Genome Editing Technologies in Soybean (Glycine max L.) for Abiotic Stress Tolerance
Soybean (Glycine max L.) is one of the five major cultivated crops that are important in the world, and it is also a major source of oil and protein...
-
RNAi-Based Biopesticides: A Review of Recent Studies in Lepidopteran Insects
It is well recognized that synthetic chemical pesticides are crucial in the control of insect pests. However, their detrimental effects on the...
-
Expanding Horizons: Role of Biotechnology in MAP Research, Production and Utilization
Plant tissue culture (PTC) plays a vital role in selection, multiplication, and conservation of the critical genotypes of medicinal plants. These...
-
Prediction of prime editing insertion efficiencies using sequence features and DNA repair determinants
Most short sequences can be precisely written into a selected genomic target using prime editing; however, it remains unclear what factors govern...
-
Gene Editing
Gene editing is a technique of genetic engineering when a particular fragment of DNA is either inserted, replaced, or removed from a genome using...
-
Innovations in Artificial Induction of Plant Genetic Diversity
Plant breeding aimed at crop improvement is dependent upon the genetic variability in the available genetic resources. This is essentially required...
-
Gene editing tool kit in millets: present status and future directions
Millets, the sixth most-grown group of crops in the drylands, support the livelihood of many small-holder farmers in the region. Being one of the...
