Search
Search Results
-
Principal neuron diversity in the murine lateral superior olive supports multiple sound localization strategies and segregation of information in higher processing centers
Principal neurons (PNs) of the lateral superior olive nucleus (LSO) in the brainstem of mammals compare information between the two ears and enable...
-
Icariside II promotes the differentiation of human amniotic mesenchymal stem cells into dopaminergic neuron-like cells
The purpose of this study is to observe the effect of icariside II (ICS II) on the differentiation of human amniotic mesenchymal stem cells (hAMSCs)...
-
Telomerase reverse transcriptase preserves neuron survival and cognition in Alzheimer’s disease models
Amyloid-induced neurodegeneration plays a central role in Alzheimer’s disease (AD) pathogenesis. Here, we show that telomerase reverse transcriptase (
-
Insulin signalling in tanycytes gates hypothalamic insulin uptake and regulation of AgRP neuron activity
Insulin acts on neurons and glial cells to regulate systemic glucose metabolism and feeding. However, the mechanisms of insulin access in discrete...
-
Neuron derived fractalkine promotes microglia to absorb hematoma via CD163/HO-1 after intracerebral hemorrhage
BackgroundHematoma leads to progressive neurological deficits and poor outcomes after intracerebral hemorrhage (ICH). Early clearance of hematoma is...
-
ApoE4 (Δ272–299) induces mitochondrial‐associated membrane formation and mitochondrial impairment by enhancing GRP75-modulated mitochondrial calcium overload in neuron
BackgroundApolipoprotein E4 (apoE4) is a major genetic risk factor of Alzheimer’s disease. Its C-terminal-truncated apoE4 (Δ272–299) has...
-
Neuron navigator 3 (NAV3) is required for heart development in zebrafish
As a tightly controlled biological process, cardiogenesis requires the specification and migration of a suite of cell types to form a particular...
-
CRABP1-CaMKII-Agrn regulates the maintenance of neuromuscular junction in spinal motor neuron
Cellular retinoic acid-binding protein 1 (CRABP1) binds retinoic acid (RA) specifically in the cytoplasm with unclear functions. CRABP1 is highly and...
-
Omi inhibition ameliorates neuron apoptosis and neurological deficit after subarachnoid hemorrhage in rats
BackgroundSubarachnoid hemorrhage (SAH) is a severe neurological emergency, resulting in cognitive impairments and threatening human's health....
-
miR-204-5p is sponged by TUG1 to aggravate neuron damage induced by focal cerebral ischemia and reperfusion injury through upregulating COX2
Studies have reported that miR-204-5p is involved in multiple biological processes. However, little is known about the expression and mechanism of...
-
Optogenetics to Interrogate Neuron-Glia Interactions in Pups and Adults
In just over 10 years, the use of optogenetic technologies in neuroscience has become widespread, having today a tremendous impact on our...
-
Sexual excitation induces courtship ultrasonic vocalizations and cataplexy-like behavior in orexin neuron-ablated male mice
Cataplexy is triggered by laughter in humans and palatable food in mice. To further evaluate mice’s cataplexy, we examined courtship behavior in...
-
Motor Unit Number Index (MUNIX): A Biomarker for Evaluation of Lower Motor Neuron Involvement in Amyotrophic Lateral Sclerosis
AbstractAlthough multiple clinical trials of various therapeutic interventions in amyotrophic lateral sclerosis (ALS) have been conducted so far,...
-
Improvement of damaged cavernosa followed by neuron-like differentiation at injured cavernous nerve after transplantation of stem cells seeded on the PLA nanofiber in rats with cavernous nerve injury
This study investigated the differentiation of transplanted transplanted mesenchymal stem cells MSCs into neuron-like cells, repair of erectile...
-
Sex-dimorphic moderate hypoglycemia preconditioning effects on Hippocampal CA1 neuron bio-energetic and anti-oxidant function
Hypoglycemia is a detrimental complication of rigorous management of type 1 diabetes mellitus. Moderate hypoglycemia (MH) preconditioning of male...
-
Mettl14-mediated m6A modification modulates neuron apoptosis during the repair of spinal cord injury by regulating the transformation from pri‐mir‐375 to miR-375
BackgroundSpinal cord injury (SCI) is a disabling disorder, resulting in neurological impairments. This study investigated the mechanism of...
-
Numerical analysis of conduction velocity/path relationships in a crustacean sensory neuron
Experimental observations of the axonal conduction velocities of sensory neurons associated with near-field sensilla on the cephalothorax of the...
-
Amyloidosis increase is not attenuated by long-term calorie restriction or related to neuron density in the prefrontal cortex of extremely aged rhesus macaques
As human lifespan increases and the population ages, diseases of aging such as Alzheimer’s disease (AD) are a major cause for concern. Although...
