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miRNA Regulatory Networks Underlying the Root–Leaf Synergism in Salt Tolerant Pokkali Rice
Pokkali is one of the rice varieties that have adapted to grow under highly saline conditions. Several studies have shown that plant’s response to...
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Integrated analysis of the expression profiles of the lncRNA-miRNA-mRNA ceRNA network in granulosa and cumulus cells from yak ovaries
BackgroundGrowing oocytes acquire the ability to mature through two-way communication between gametes and surrounding somatic cumulus cells (CCs)....
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The fluctuations of expression profiles of critical genes in the miRNA maturation process and pro-and anti-inflammatory cytokines in the pathogenesis and progression of multiple sclerosis
BackgroundMultiple sclerosis (MS) is a central nervous system disease known for immune-mediated demyelination, inflammatory, and neurodegeneration...
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Overview of Computational and Experimental Methods to Identify Tissue-Specific MicroRNA Targets
As ubiquitous posttranscriptional regulators of gene expression, microRNAs (miRNAs) play key roles in cell physiology and function across taxa. In...
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Heterosis of growth trait regulated by DNA methylation and miRNA in allotriploid fish
BackgroundHeterosis of growth traits in allotriploid fish has benefited the production of aquaculture for many years, yet its genetic and molecular...
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Identification and characterization of circular RNAs in association with the feed efficiency in Hu lambs
BackgroundCircular RNA (circRNA), as a new members of noncoding RNA family, have vital functions in many biological processes by as microRNA sponges...
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Oviductal extracellular vesicles miRNA cargo varies in response to embryos and their quality
BackgroundIncreasing evidence points to an active role of oviductal extracellular vesicles (oEVs) in the early embryo-maternal dialogue. However, it...
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Regulation of pri-MIRNA processing: mechanistic insights into the miRNA homeostasis in plant
miRNAs in plant plays crucial role in controlling proper growth, development and fitness by modulating the expression of their target genes....
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A-to-I RNA editing shows dramatic up-regulation in osteosarcoma and broadly regulates tumor-related genes by altering microRNA target regions
A-to-I RNA editing is a prevalent type of RNA modification in animals. The dysregulation of RNA editing has led to multiple human cancers. However,...
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Prediction of on-target and off-target activity of CRISPR–Cas13d guide RNAs using deep learning
Transcriptome engineering applications in living cells with RNA-targeting CRISPR effectors depend on accurate prediction of on-target activity and...
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Myc manipulates the miRNA content and biologic functions of small cell lung cancer cell-derived small extracellular vesicles
BackgroundMYC genes are amplified/overexpressed in 20% of SCLCs, showing that Myc and Myc-dependent cellular mechanisms are strong candidates as...
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Maize miRNAs and their putative target genes involved in chilling stress response in 5-day old seedlings
BackgroundIn the context of early sowing of maize as a promising adaptation strategy that could significantly reduce the negative effects of climate...
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Advances in studies of circulating microRNAs: origination, transportation, and distal target regulation
In the past few years, numerous advances emerged in terms of circulating microRNA(miRNA) regulating gene expression by circulating blood to the...
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Effects of salinity acclimation on histological characteristics and miRNA expression profiles of scales in juvenile rainbow trout (Oncorhynchus mykiss)
BackgroundThe scales serve as an ideal model for studying the regulatory mechanism of bone homeostasis in fish. To explore the effect of salinity...
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Determining extracellular vesicles properties and miRNA cargo variability in bovine milk from healthy cows and cows undergoing subclinical mastitis
BackgroundSubclinical mastitis, the inflammation of the mammary gland lacking clinical symptoms, is one of the most prevalent and costly diseases in...
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Genome-wide development and application of miRNA-SSR markers in Melilotus genus
Genetic diversity of plants is the brace of biodiversity and diversity within species, between species, and of ecosystems. SSR markers are the most...
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miRNA sequencing analysis of healthy and atretic follicles of chickens revealed that miR-30a-5p inhibits granulosa cell death via targeting Beclin1
BackgroundThe egg production performance of chickens is affected by many factors, including genetics, nutrition and environmental conditions. These...
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Methylated lncRNAs suppress apoptosis of gastric cancer stem cells via the lncRNA–miRNA/protein axis
BackgroundLong noncoding RNAs (lncRNAs) play essential roles in the tumorigenesis of gastric cancer. However, the influence of lncRNA methylation on...
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Isolation of Cardiomyocytes Derived from Human Pluripotent Stem Cells Using miRNA Switches
The most common method for isolating cells of interest is an antibody method that recognizes cell surface antigens. However, specific surface...
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Inferring the regulatory network of the miRNA-mediated response to individual and combined heat and drought stress in tomato
Under natural environmental conditions, plants are prone to be challenged simultaneously by combination of stresses like heat and drought stress...
