Search
Search Results
-
The transcription factor reservoir and chromatin landscape in activated plasmacytoid dendritic cells
BackgroundTranscription factors (TFs) control gene expression by direct binding to regulatory regions of target genes but also by impacting chromatin...
-
Effect of soybean proteins and peptides on the growth and adhesive ability of Limosilactobacillus Reuteri DSM17938
Limosilactobacillus reuteri DSM17938 is one of the most pivotal probiotics, whose general beneficial effects on the intestinal microbiota are well...
-
LFA-1 knockout inhibited the tumor growth and is correlated with treg cells
Cancer immunotherapy has been proven to be clinically effective in multiple types of cancers. Lymphocyte function-associated antigen 1 (LFA-1), a...
-
Viruses exploit growth factor mechanisms to achieve augmented pathogenicity and promote tumorigenesis
Cellular homeostasis is regulated by growth factors (GFs) which orchestrate various cellular processes including proliferation, survival,...
-
Lipocalin 2 regulates expression of MHC class I molecules in Mycobacterium tuberculosis-infected dendritic cells via ROS production
BackgroundIron has important roles as an essential nutrient for all life forms and as an effector of the host defense mechanism against pathogenic...
-
Lymphatic endothelial-like cells promote glioblastoma stem cell growth through cytokine-driven cholesterol metabolism
Glioblastoma is the most lethal primary brain tumor with glioblastoma stem cells (GSCs) atop a cellular hierarchy. GSCs often reside in a...
-
Activating STING/TBK1 suppresses tumor growth via degrading HPV16/18 E7 oncoproteins in cervical cancer
Cervical cancer is the most common gynecologic cancer, etiologically related to persistent infection of human papillomavirus (HPV). Both the host...
-
Neurotrophin growth factors and their receptors as promising blood biomarkers for Alzheimer’s Disease: a gene expression analysis study
BackgroundAlzheimer’s disease (AD) is a multifaceted neurological ailment affecting more than 50 million individuals globally, distinguished by a...
-
Effects of dietary supplementation of cobiotic based on Agave fructans on growth performance, blood parameters, oxidative damage and immune status of broiler
This study evaluated the effect of cobiotic (CO) composed of organic fructans powder of Agave tequilana and turmeric powder of Curcuma longa L. as an...
-
Mesenchymal Stem Cells, Cancer Stem Cells (CSCs), and Circulating Tumor Cells (CTCs): Roles and Combinations in Tumor Growth and Dissemination
Mesenchymal stem cells are considered the key cells in tissue regeneration after damage. MSCs play a fundamental role in cancer since they can be...
-
Mesenchymal stem cell-derived exosomes decrease Hyperplasia in Psoriasis by inducing transforming growth factor β2 (TGF-β2)
BackgroundPsoriasis, a chronic inflammatory skin disease, is increasingly effectively managed with the targeted immunotherapy; however, long-term...
-
A Novel Heat Shock Protein 70-Based Vaccine Prepared from DC Tumor Fusion Cells: An Update
We have developed an enhanced molecular chaperone-based vaccine through rapid isolation of Hsp70 peptide complexes after the fusion of tumor and...
-
Microgravity studies of solidification patterns in model transparent alloys onboard the International Space Station
We review recent in situ solidification experiments using nonfaceted model transparent alloys in science-in-microgravity facilities onboard the...
-
Ex Vivo Immunomodulatory Effects of Lactobacillus-, Lacticaseibacillus-, and Bifidobacterium-Containing Synbiotics on Human Peripheral Blood Mononuclear Cells and Monocyte-Derived Dendritic Cells in the Context of Grass Pollen Allergy
Sensing of the intestinal microbiota by the host immune system is important to induce protective immune responses. Hence, modification of the gut...
-
GPR120 induces regulatory dendritic cells by inhibiting HK2-dependent glycolysis to alleviate fulminant hepatic failure
Fulminant hepatic failure (FHF) is a potentially fatal liver disease that is associated with intrahepatic infiltration of inflammatory cells. As the...
-
Bilirubin impairs neuritogenesis and synaptogenesis in NSPCs by downregulating NMDAR-CREB-BDNF signaling
Neonatal jaundice is one of the most common disorders in the first 2 wk after birth. Unconjugated bilirubin (UCB) is neurotoxic and can cause...
-
Isolation and identification of Bacillus and abilities of 3 functional strains to control powdery mildew and promote seedling growth of Malus sieversii
To effectively control the powdery mildew ( Podosphaera leucotricha ) of Malus sieversii (Msi) and promote the growth of Msi seedlings, 170 Bacillus ...
-
Integrin-dependent migratory switches regulate the translocation of Toxoplasma-infected dendritic cells across brain endothelial monolayers
Multiple cellular processes, such as immune responses and cancer cell metastasis, crucially depend on interconvertible migration modes. However,...
-
Essential role of submandibular lymph node dendritic cells in protective sublingual immunotherapy against murine allergy
While sublingual immunotherapy (SLIT) is known as an allergen-specific treatment for type-1 allergies, how it controls allergic pathogenesis remains...
-
Metabolic Messengers: fibroblast growth factor 1
While fibroblast growth factor (FGF) 1 is expressed in multiple tissues, only adipose-derived and brain FGF1 have been implicated in the regulation...
