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Genome-wide differential DNA methylation analysis of MDA-MB-231 breast cancer cells treated with curcumin derivatives, ST08 and ST09
ST08 and ST09 are potent curcumin derivatives with antiproliferative, apoptotic, and migrastatic properties. Both ST08 and ST09 exhibit in vitro and...
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Chitosan Microspheres Loaded with Curcumin and Gallic Acid: Modified Synthesis, Sustainable Slow Release, and Enhanced Biological Property
Improving the utilization rate of loaded-drugs is of huge importance for generating chitosan-based (CS) micro-carriers. This study aims to fabricate...
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Development of soy protein/sodium alginate nanogel-based cress seed gum hydrogel for oral delivery of curcumin
BackgroundIn order to deliver bioactive compounds with better thermal stability and delayed release characteristics, nanogels can be placed inside a...
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Cellular uptake and apoptotic properties of gemini curcumin in gastric cancer cells
IntroductionCurcumin is a polyphenolic natural compound, which has demonstrated to possess antioxidant, anti-inflammatory, and anticancer effects in...
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Antidiabetic Properties of Curcumin: Insights on New Mechanisms
Plant extracts have been used to treat a wide range of human diseases. Curcumin, a bioactive polyphenol derived from Curcuma longa L., exhibits...
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Unveiling the emerging role of curcumin to alleviate ochratoxin A-induced muscle toxicity in grass carp (Ctenopharyngodon idella): in vitro and in vivo studies
BackgroundOchratoxin A (OTA), a globally abundant and extremely hazardous pollutant, is a significant source of contamination in aquafeeds and is...
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Curcumin: A Review of Its Effects on Epilepsy
Central nervous system (CNS) diseases pose an enormous healthcare burden, at both an individual and a societal level. Epilepsy has now become one of...
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Combination of Curcumin and Zerumbone Improves VEGF-A Inhibition in Colorectal Cancer In Vivo and In Vitro Model
Colorectal cancer (CRC) is reliant on several molecular pathways, which may develop distinct mechanisms of resistance to single-agent treatment. In...
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Turmeric and Curcumin: From Traditional to Modern Medicine
The rhizome of turmeric (Curcuma longa L.) has been used as an herbal medicine, coloring agent, spice, and food additive for thousands of years in...
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Antibacterial Activity of Curcumin Against Periodontal Pathogens: A Systematic Review
Periodontitis is a chronic inflammatory disease characterized by destruction of the supporting structures of teeth caused by development of dental...
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Carbon-based Nanomaterials and Curcumin: A Review of Biosensing Applications
Curcumin, the main active constituent of turmeric (Curcuma longa L.), is a naturally occurring phenolic compound with a wide variety of...
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Interleukin-4 from curcumin-activated OECs emerges as a central modulator for increasing M2 polarization of microglia/macrophage in OEC anti-inflammatory activity for functional repair of spinal cord injury
Microglia/macrophages are major contributors to neuroinflammation in the central nervous system (CNS) injury and exhibit either pro- or...
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Telomerase: A Target for Therapeutic Effects of Curcumin in Cancer
Telomerases are attractive targets for development of new anticancer agents. Most tumors express the enzyme telomerase that maintains telomere length...
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Antibacterial activity of supernatants of Lactoccocus lactis, Lactobacillus rhamnosus, Pediococcus pentosaceus and curcumin against Aeromonas hydrophila. In vitro study
Secretions of beneficial intestinal bacteria can inhibit the growth and biofilm formation of a wide range of microorganisms. Curcumin has shown broad...
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Retinal ganglion cell loss in an ex vivo mouse model of optic nerve cut is prevented by curcumin treatment
Retinal ganglion cell (RGC) loss is a pathologic feature common to several retinopathies associated to optic nerve damage, leading to visual loss and...
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Synthetic curcumin analog: inhibiting the invasion, angiogenesis, and metastasis in human laryngeal carcinoma cells via NF-kB pathway
BackgroundLaryngeal carcinoma, the most common among head and neck squamous cell carcinoma (HNSCC), induces 1% of all cancer deaths. Curcumin the...
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Insecticidal effects of Curcumin (Curcuma longa) against the horse stomach bot fly, Gasterophilus intestinalis (Diptera: Oestridae)
Stomach horse bots ( Gasterophilus intestinalis larvae; Diptera: Oestridae) are obligatory parasites inhabit the stomach of domestic Equidae ....
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In vitro and in silico analysis reveals antifungal activity and potential targets of curcumin on Paracoccidioides spp.
The search for new compounds with activity against Paracoccidioides , etiologic agents of Paracoccidioidomycosis (PCM), is extremely necessary due to...
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Effects of Curcumin and Its Analogues on Infectious Diseases
Infectious diseases (IDs) are life-threatening illnesses, which result from the spread of pathogenic microorganisms such as bacteria, viruses, fungi,...
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Protective Effects of Curcumin on Endothelium: An Updated Review
Endothelial dysfunction is the common early stage of most cardiovascular afflictions. The endothelium is considered the main mediator of vascular...