Search
Search Results
-
Anti-stress effects of Fameyes in in vitro and in vivo models of stresses
BackgroundFameyes (a mixture of Clematis mandshurica Rupr. extract (CMRE) and Erigeron annuus (L.) Pers. extract (EAPE)) containing scutellarin and...
-
Deep learning-based mixed-dimensional Gaussian mixture model for characterizing variability in cryo-EM
Structural flexibility and/or dynamic interactions with other molecules is a critical aspect of protein function. Cryogenic electron microscopy...
-
3D tissue-engineered lung models to study immune responses following viral infections of the small airways
Small airway infections caused by respiratory viruses are some of the most prevalent causes of illness and death. With the recent worldwide pandemic...
-
Temperature-dependent development of Agrotis ipsilon (Lepidoptera: Noctuidae) and its stage transition models
The black cut worm Agrotis ipsilon (Hufnagel) is a destructive crop pest worldwide and a typical cut worm damaging plant parts below the soil...
-
Anesthesia and analgesia for common research models of adult mice
Anesthesia and analgesia are major components of many interventional studies on laboratory animals. However, various studies have shown improper...
-
Utilizing hydrothermal time models to assess the effects of temperature and osmotic stress on maize (Zea mays L.) germination and physiological responses
The application of germination models in economic crop management makes them extremely useful for predicting seed germination. Hence, we examined the...
-
Rhizosphere models: their concepts and application to plant-soil ecosystems
BackgroundThe rhizosphere is the influence-sphere of the root. It is a local ecosystem with complex functions that determine nutrient uptake, cycling...
-
Generalized Linear Mixed Models for Longitudinal Microbiome Data
Chapter 16 investigated some general topics of generalized linear mixed-effects models (GLMMs). This chapter...
-
Assignment of unimodal probability distribution models for quantitative morphological phenoty**
BackgroundCell morphology is a complex and integrative readout, and therefore, an attractive measurement for assessing the effects of genetic and...
-
Identifying common transcriptome signatures of cancer by interpreting deep learning models
BackgroundCancer is a set of diseases characterized by unchecked cell proliferation and invasion of surrounding tissues. The many genes that have...
-
Performance of a finite mixture model in CPUE standardization for a longline fishery with target change
Standardized catch per unit effort (CPUE) is frequently used to represent annual fish-stock abundance trends. In multispecies fisheries, the...
-
Leveraging Tissue Engineering for Skin Cancer Models
Bioengineered in vitro three-dimensional (3D) skin model has emerged as a promising tool for recapitulating different types of skin cancer and...
-
Representing Insect Movement in Agricultural Areas using Spatially Explicit Models
Understanding the movement of organisms is fundamental for comprehending how life thrives and the changes in population dynamics of a species. It is...
-
Complementary and Inducible creERT2 Mouse Models for Functional Evaluation of Endothelial Cell Subtypes in the Bone Marrow
In the adult bone marrow (BM), endothelial cells (ECs) are an integral component of the hematopoietic stem cell (HSC)-supportive niche, which...
-
Inhibition of TRAF6 improves hyperlipidemic acute pancreatitis by alleviating pyroptosis in vitro and in vivo rat models
ObjectiveHypertriglyceridemia (HTG) is one of the common causes of acute pancreatitis (AP). Hyperlipidemic acute pancreatitis (HTG-AP) is associated...
-
A small-molecule TNIK inhibitor targets fibrosis in preclinical and clinical models
Idiopathic pulmonary fibrosis (IPF) is an aggressive interstitial lung disease with a high mortality rate. Putative drug targets in IPF have failed...
-
Optimal precision and accuracy in 4Pi-STORM using dynamic spline PSF models
Coherent fluorescence imaging with two objective lenses (4Pi detection) enables single-molecule localization microscopy with sub-10 nm spatial...
-
Microglial MHC-I induction with aging and Alzheimer’s is conserved in mouse models and humans
Major histocompatibility complex I (MHC-I) CNS cellular localization and function is still being determined after previously being thought to be...
-
Comprehensive characterization of the neurogenic and neuroprotective action of a novel TrkB agonist using mouse and human stem cell models of Alzheimer’s disease
BackgroundNeural stem cell (NSC) proliferation and differentiation in the mammalian brain decreases to minimal levels postnatally. Nevertheless,...
-
Aesthetic preference for art can be predicted from a mixture of low- and high-level visual features
It is an open question whether preferences for visual art can be lawfully predicted from the basic constituent elements of a visual image. Here, we...
