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Modeling Xylem Functionality Aspects
Depending on the questions to be answered, water flow in the xylem can be modelled following different approaches with varying spatial and temporal... -
Characterization and potential mechanism of resistance to double-stranded RNA in willow leaf beetle, Plagiodera versicolora
RNAi-based pesticides have emerged gradually in recent decades and are believed to be the next generation of pesticides. Although resistance to RNA...
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Modeling Spatial Niches of Small Mammals Using the Example of Myodes glareolus in Mosaic Southern Taiga Forests
AbstractBased on long-term (2010–2014) studies carried out in the forest ecosystems of the Central Forest Biosphere Reserve, two models of the...
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Multigenic resistance to Xylella fastidiosa in wild grapes (Vitis sps.) and its implications within a changing climate
Xylella fastidiosa is a bacterium that infects crops like grapevines, coffee, almonds, citrus and olives. There is little understanding of the genes...
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Reversal of gentamicin sulfate resistance in avian pathogenic Escherichia coli by matrine combined with berberine hydrochloride
In recent years, the evolution of antibiotic resistance has led to the inefficacy of several antibiotics, and the reverse of resistance was a novel...
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Exploring the resistome, virulome, and mobilome of multidrug-resistant Klebsiella pneumoniae isolates: deciphering the molecular basis of carbapenem resistance
BackgroundKlebsiella pneumoniae , a notorious pathogen for causing nosocomial infections has become a major cause of neonatal septicemia, leading to...
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Rice WRKY13 TF protein binds to motifs in the promoter region to regulate downstream disease resistance-related genes
In plants, pathogen resistance is brought about by the binding of certain transcription factor (TF) proteins to the cis -elements of certain target...
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Single-cell characterization of step-wise acquisition of carboplatin resistance in ovarian cancer
The molecular underpinnings of acquired resistance to carboplatin are poorly understood and often inconsistent between in vitro modeling studies....
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Draft genome sequence of novel Candidatus Ornithobacterium hominis carrying antimicrobial resistance genes in Egypt
BackgroundCandidatus Ornithobacterium hominis ( O. hominis ), which was identified in nasopharyngeal swabs from Egypt, has been associated with...
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Insect-Resistance of Aquilaria sinensis (Lour.) Leaves is Associated with Volatile Compounds
AbstractAquilaria sinensis (Lour.) is listed as a nationally endangered plant in China. Heortia vitessoides (Moore) is an important monophagous...
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Comparative assessment of different anti-CD147/Basigin 2 antibodies as a potential therapeutic anticancer target by molecular modeling and dynamic simulation
Cluster of differentiation 147 (CD147) is an attractive target for anticancer therapy since it is pivotal in develo** and progressing several of...
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Cytochrome P450 CYP709C56 metabolizing mesosulfuron-methyl confers herbicide resistance in Alopecurus aequalis
Multiple herbicide resistance in diverse weed species endowed by enhanced herbicide detoxification or degradation is rapidly growing into a great...
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Toward combining qualitative race-specific and quantitative race-nonspecific disease resistance by genomic selection
Key messageA novel genomic selection strategy offers the unique opportunity to develop qualitative race-specific resistant varieties that possess...
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Modeling of the brain-lung axis using organoids in traumatic brain injury: an updated review
Clinical outcome after traumatic brain injury (TBI) is closely associated conditions of other organs, especially lungs as well as degree of brain...
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Modeling habitat suitability across different levels of invasive plant abundance
Predicting where invasive plants are likely to spread and become abundant is critical for informing invasive plant management. Species distribution...
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A deep learning model of tumor cell architecture elucidates response and resistance to CDK4/6 inhibitors
Cyclin-dependent kinase 4 and 6 inhibitors (CDK4/6is) have revolutionized breast cancer therapy. However, <50% of patients have an objective...
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Field resistance to boscalid and molecular mechanisms of strawberry Botrytis cinerea in Chongqing, China
Gray mold is a common and severe disease that affects strawberry production and storage. To clarify the occurrence and mechanism of Botrytis cinerea ...
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Multi-omics assisted breeding for biotic stress resistance in soybean
Biotic stress is a critical factor limiting soybean growth and development. Soybean responses to biotic stresses such as insects, nematodes, fungal,...
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Molecular modeling of aquaporins and artificial transmembrane channels: a mini-review and perspective for plants
Aquaporins (AQPs) are a family of transmembrane channels found across various kingdoms, including archaea, eubacteria, fungi, plants, and animals....