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Molecular Mechanism of the Circadian Clock
Nearly all organisms possess a circadian clock, a genetically determined device that generates endogenous oscillations with a period of approximately...
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Advances in the Study of Etiology and Molecular Mechanisms of Sensorineural Hearing Loss
Sensorineural hearing loss (SNHL), a multifactorial progressive disorder, results from a complex interplay of genetic and environmental factors, with...
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The Impact of D614G Mutation of SARS-COV-2 on the Efficacy of Anti-viral Drugs: A Comparative Molecular Docking and Molecular Dynamics Study
D614G is one of the most reported mutations in the spike protein of SARS-COV-2 that has altered some crucial characteristics of coronaviruses, such...
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DEL variants: review of molecular mechanisms, clinical consequences and molecular testing strategy
Patients with DEL phenotype, a D variant with a low number of D antigens per red blood cell, are routinely typed as RhD-negative in serology testing...
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Exploring chalcone-sulfonyl piperazine hybrids as anti-diabetes candidates: design, synthesis, biological evaluation, and molecular docking study
To address the escalating rates of diabetes mellitus worldwide, there is a growing need for novel compounds. The demand for more affordable and...
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Genome-wide association study and development of molecular markers for yield and quality traits in peanut (Arachis hypogaea L.)
BackgroundThis study aims to decipher the genetic basis governing yield components and quality attributes of peanuts, a critical aspect for advancing...
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Molecular Systematics of Parasitic Nematodes
The study of molecular systematicsSystematics, where the concept was first introduced in Chap. 1 , enables the...
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Applications of Molecular Biology in Agriculture
Detailed knowledge of the processes involved in the central dogma of molecular biology has enabled the direct or indirect use of DNA in molecular...
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Artificial intelligence assisted identification of potential tau aggregation inhibitors: ligand- and structure-based virtual screening, in silico ADME, and molecular dynamics study
Alzheimer’s disease (AD) is a severe, growing, multifactorial disorder affecting millions of people worldwide characterized by cognitive decline and...
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Molecular Mechanisms of Pyroptosis
Pyroptosis is a regulated form of cell death that leads to inflammation and plays a role in many different diseases. Pyroptosis was initially defined...
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A comprehensive molecular docking-based study to identify potential drug-candidates against the novel and emerging severe fever with thrombocytopenia syndrome virus (SFTSV) by targeting the nucleoprotein
Severe fever with thrombocytopenia syndrome (SFTS) is a newly emerging haemorrhagic fever that is caused by an RNA virus called Severe fever with...
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Insecticidal Evaluation, Molecular Docking, and Structure-Activity Relationship Study of Some Synthesized Thiazole-Owing Hydrazone Derivatives Against Spodoptera frugiperda under Laboratory Conditions
AbstractObjective: The “fall armyworm” also known as Spodoptera frugiperda, is a maize pest that is native to North America. It invaded Africa in...
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Molecular Aspects of Mulberry
Mulberry (Morus spp.) is highly recognized as an economical cash crop plant species due to its wide utilization in “sericulture,” food, and beverage...
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Repositioning of anti-infective compounds against monkeypox virus core cysteine proteinase: a molecular dynamics study
Monkeypox virus (MPXV) core cysteine proteinase (CCP) is one of the major drug targets used to examine the inhibitory action of chemical moieties. In...
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Cardioprotective Effect of Eugenol Against Cd-Induced Inflammation, Oxidative Stress, and Dyslipidemia in Male Rats: An In Vivo and Molecular Docking Study
Cadmium, a highly toxic heavy metal, can cause severe damage to several vital organs including the kidney, liver, and brain. Many of the natural...
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Plant Molecular Farming: A Boon for Develo** Countries
Develo** countries are often at the back of the queue to receive much-needed vaccines and diagnostics. This chapter discusses the diseases...
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Modeling Protein Complexes and Molecular Assemblies Using Computational Methods
Many biological molecules are assembled into supramolecular complexes that are necessary to perform functions in the cell. Better understanding and...
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Molecular dynamics study of collective water vibrations in a DNA hydration shell
The structure of DNA double helix is stabilized by water molecules and metal counterions that form the ion-hydration shell around the macromolecule....
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Molecular complexity of diffuse large B-cell lymphoma: a molecular perspective and therapeutic implications
Diffuse large B-cell lymphoma (DLBCL) stands as a formidable challenge in the landscape of non-Hodgkin’s lymphomas. This review illuminates the...
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Bacteriological and molecular study of fosfomycin resistance in uropathogenic Escherichia coli
The identification of genes associated with resistance has the potential to facilitate the development of novel diagnostic tests and treatment...
