Search
Search Results
-
Changes in extra cellular matrix remodelling and re-expression of fibronectin and tenascin-C splicing variants in human myocardial tissue of the right atrial auricle: implications for a targeted therapy of cardiovascular diseases using human SIP format antibodies
Cardiovascular diseases are accompanied by changes in the extracellular matrix (ECM) including the re-expression of fibronectin and tenascin-C...
-
Digital BioCuration: A Question of Balance
Curation of biomedical data has come to encompass a broad range of activities and considerations, which include the building of digital archives,...
-
Molecular Cytogenetic Applications in Diagnostics and Research: An Overview
Molecular cytogenetics is a new branch of chromosome research that is just is just over 25 years old. Current applications of fluorescence in situ...
-
Hereditary haemochromatosis gene (HFE) H63D mutation shows an association with abnormal sperm motility
The aim of this study was to screen infertile men for HFE H63D mutation in correlation with clinical characteristics of infertile men (sperm...
-
FGFR1 and anosmin-1 underlying genetically distinct forms of Kallmann syndrome are co-expressed and interact in olfactory bulbs
Kallmann syndrome is a genetically heterogeneous developmental disease characterised by a partial or complete lack of olfactory bulb development. Two...
-
Nose thyself: individuality in the human olfactory genome
A recent study using cell-based assays together with an olfactory psychophysical survey in humans has established a link between a genetic...
-
Biological Function of Prokineticins
Secreted peptides have been implicated in diverse physiological functions. Prokineticins are a pair of regulatory peptides that signal through...
-
GPR54 and Kisspeptins
The G-protein coupled receptor GPR54 has an essential role in the initiation and maintenance of mammalian fertility. Humans and mice with...
-
Kallmann’s syndrome, a neuronal migration defect
Infertility and inability to smell are the phenotypical features of Kallmann’s syndrome (KS), a genetic disease which affects 1 in 10,000 males and 1...
-
Krankheiten des endokrinen Systems
Das Hormonsystem ist mit den elementaren Körperfunktionen so eng verknüpft, dass Defekte des endokrinen Systems zu Krankheiten bis hin zum Tod...
-
"NeuroStem Chip": a novel highly specialized tool to study neural differentiation pathways in human stem cells
BackgroundHuman stem cells are viewed as a possible source of neurons for a cell-based therapy of neurodegenerative disorders, such as Parkinson's...
-
Signaling in the Chemosensory Systems
Of all five senses, olfaction is the most complex molecular mechanism, as it comprises hundreds of receptor proteins enabling it to detect and...
-
Genome-wide gene expression profiling of human mast cells stimulated by IgE or FcεRI-aggregation reveals a complex network of genes involved in inflammatory responses
BackgroundMast cells are well established effectors of IgE-triggered allergic reactions and immune responses to parasitic infections. Recent studies...
-
Branching Morphogenesis in Vertebrate Neurons
Within the develo** vertebrate nervous system, strict control of branching morphogenesis is essential for establishing appropriate circuitry, since...
-
Chromosomenstörungen
Chromosomenstörungen sind beim Menschen keine Seltenheit. Etwa 20 % aller Konzeptionen haben Chromosomenanomalien, jedoch wird der größte Teil dieser...
-
Modular Assembly of Genes and the Evolution of New Functions
Modular assembly of novel genes from existing genes has long been thought to be an important source of evolutionary novelty. Thanks to major advances...
-
Modular assembly of genes and the evolution of new functions
Modular assembly of novel genes from existing genes has long been thought to be an important source of evol- utionary novelty. Thanks to major...
-
The olfactory bulb as an independent developmental domain
The olfactory system is a good model to study the mechanisms underlying guidance of growing axons to their appropriate targets. The formation of the...
-
