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Hepatitis C-associated Osteosclerosis (HCAO): Long-Term Follow-Up of a New Case Recovered After Antiviral Treatment
Hepatitis C-associated osteosclerosis (HCAO) is a very rare condition that can be observed in a small number of patients with Hepatitis C Virus (HCV)...
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A combined inactivated cholera and hepatitis A vaccine-induced potent protective immunity in a mouse model
AbstractCholera and hepatitis A are serious infections spread by consuming contaminated food or water. Vaccination is the most effective strategy to...
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Janus kinase inhibitor Tofacitinib alleviated acute hepatitis induced by lipopolysaccharide/D-galactosamine in mice
Background:The Janus kinase (JAK) is a crucial intracellular signaling hub for numerous cytokines, which is extensively involved in the activation of...
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Hepatitis E virus in wild and domestic rabbits from Portugal: a combined molecular and longitudinal serological study
Hepatitis E virus (HEV), species Paslahepevirus balayani , poses a global public health threat, especially in develo** countries, by causing acute...
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Identification of Mulberrofuran as a potent inhibitor of hepatitis A virus 3Cpro and RdRP enzymes through structure-based virtual screening, dynamics simulation, and DFT studies
Hepatitis is a medical condition characterized by inflammation of the liver. It is commonly caused by the hepatitis viruses A, B, C, D, and E....
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Association between MTTP genotype (-493G/T) polymorphism and hepatic steatosis in hepatitis C: a systematic review and meta-analysis
BackgroundHepatitis C has been associated with the development of hepatic steatosis, which increases the risk of liver cancer. The microsomal...
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GSDMD induces hepatocyte pyroptosis to trigger alcoholic hepatitis through modulating mitochondrial dysfunction
BackgroundMechanisms and consequences of Gasdermin D (GSDMD) activation in alcoholic hepatitis (AH) are unclear. In the present study, we...
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Hepatocyte steatosis inhibits hepatitis B virus secretion via induction of endoplasmic reticulum stress
The effects of hepatocyte steatosis on hepatitis B virus (HBV) DNA replication and HBV-related antigen secretion are incompletely understood. The...
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Analyzing energetics and dynamics of hepatitis C virus polymerase interactions with marine bacterial compounds: a computational study
Hepatitis C Virus (HCV) is a significant health concern affecting a large portion of the global population and is a major cause of acute liver...
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Genetic polymorphisms in the miR-372 (rs12983273) and LncRNA HULC (rs7763881) genes and susceptibility to Hepatitis B virus (HBV) infection
BackgroundMicroRNAs (miRNAs) and Long non-coding RNAs (lncRNAs) are two major types of non-coding RNAs (ncRNAs) with regulatory roles. The initiation...
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Genetic polymorphism of HLA-DRA and alcohol consumption affect hepatitis development in the Korean population
BackgroundHepatitis is an inflammation of the liver that has several potential causes; however, the genetic association has recently begun to be...
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Hepatitis B virus x gene-downregulated growth-arrest specific 5 inhibits the cell viability and invasion of hepatocellular carcinoma cell lines by activating Y-box-binding protein 1/p21 signaling
The long noncoding RNA growth-arrest specific 5 (GAS5) is a suppressor of many cancers. However, the role and mechanism of action of GAS5 in...
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Clinical stage drugs targeting inhibitor of apoptosis proteins purge episomal Hepatitis B viral genome in preclinical models
A major unmet clinical need is a therapeutic capable of removing hepatitis B virus (HBV) genome from the liver of infected individuals to reduce...
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Dynamic profile of the HBeAg-anti-HBe system in acute and chronic hepatitis B virus infection: A clinical-laboratory approach
Wild-type HBV infection is followed by the blood expression of its widely known serological markers of infection, and designated as, hepatitis B...
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The phosphatidylserine receptor TIM1 promotes infection of enveloped hepatitis E virus
The hepatitis E virus (HEV) is an underestimated RNA virus of which the viral life cycle and pathogenicity remain partially understood and for which...
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3D landscape of Hepatitis B virus interactions with human chromatins
Hepatitis B viral (HBV) DNAs, including covalently closed circular DNA (cccDNA) and integrated HBV DNA forms, are considered to be primary...
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A new dyslipidemia-based scoring model to predict transplant-free survival in patients with hepatitis E-triggered acute-on-chronic liver failure
Background/AimsHepatitis E virus (HEV)-triggered acute-on-chronic liver failure (ACLF) has unacceptably high short-term mortality. However, it is...
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Armoracia rusticana P. Gaertn., B. Mey. & Scherb. Brassicaceae
Armoracia rusticana G. Gaertn., B. Mey. & Scherb.: Armoracia armoracia Cockerell ex Daniels; Armoracia austriaca (Jacq.) Bluff, Nees & Schauer;...
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Application of a truncated ORF2 protein-based ELISA for diagnosis of hepatitis E in an endemic area
AbstractEnterically transmitted waterborne hepatitis E (HE) caused due to hepatitis E virus (HEV) prevails as a significant public health problem...
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Multiomics interrogation into HBV (Hepatitis B virus)-host interaction reveals novel coding potential in human genome, and identifies canonical and non-canonical proteins as host restriction factors against HBV
Hepatitis B Virus (HBV) constitutes a major threat to global public health. Current understanding of HBV-host interaction is yet limited. Here,...
