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Characterization of circSEC11A as a novel regulator of Iodine-125 radioactive seed-induced anticancer effects in hepatocellular carcinoma via targeting ZHX2/GADD34 axis
Iodine-125 (I-125) radioactive seed implantation is used for the local treatment of hepatocellular carcinoma (HCC), but the molecular mechanisms...
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Cystathionine β-synthase as novel endogenous regulator of lymphangiogenesis via modulating VEGF receptor 2 and 3
Lymphangiogenesis is a key player in several diseases such as tumor metastasis, obesity, and graft rejection. Endogenous regulation of...
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MilR3, a unique SARP family pleiotropic regulator in Streptomyces bingchenggensis
Streptomyces bingchenggensis is the main industrial producer of milbemycins, which are a group of 16-membered macrocylic lactones with excellent...
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Tumor suppressor let-7 acts as a key regulator for pluripotency gene expression in Muse cells
In embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), the expression of an RNA-binding pluripotency-relevant protein, LIN28, and...
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A novel regulator of wheat tillering LT1 identified by using an upgraded BSA method, uni-BSA
Branching/tillering is a critical process for plant architecture and grain yield. However, Branching is intricately controlled by both endogenous and...
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MACC1 promotes pancreatic cancer metastasis by interacting with the EMT regulator SNAI1
Metastasis is the dominant cause of cancer-related mortality. Metastasis-associated with colon cancer protein 1 (MACC1) has been proven to play a...
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The Transcription Regulator GntR/HutC Regulates Biofilm Formation, Motility and Stress Tolerance in Lysobacter capsici X2-3
Lysobacter capsici X2-3, a plant growth-promoting rhizobacteria (PGPR), was isolated from wheat rhizosphere and has inhibitory effects against a wide...
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Ions and Pollen Tube Growth
Ions play a crucial role in the control of pollen tube growth. In this review we focus on four that seem especially important: calcium (Ca...
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Autophagy: Regulator of cell death
Autophagy is the process by which cells degrade and recycle proteins and organelles to maintain intracellular homeostasis. Generally, autophagy plays...
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OsGADD45a1: a multifaceted regulator of rice architecture, grain yield, and blast resistance
Key messageThe homolog gene of the Growth Arrest and DNA Damage-inducible 45 (GADD45) in rice functions in the regulation of plant architecture,...
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Exogenously applied plant growth regulator protects rice from heat-induced damage by modulating plant defense mechanism
This study was undertaken to investigate the effect of biostimulants such as spermidine (1 mM, 2 mM), indole-3-acetic acid (10 –3 M, 10 –5 M),...
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The DREAM complex functions as conserved master regulator of somatic DNA-repair capacities
The DNA-repair capacity in somatic cells is limited compared with that in germ cells. It has remained unknown whether not only lesion-type-specific,...
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Paclobutrazol as a plant growth regulator
Plant growth regulators are chemical substances which govern all the factors of development and growth within plants. The application of plant growth...
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Regulator of G protein signaling 16 restrains apoptosis in colorectal cancer through disrupting TRAF6-TAB2-TAK1-JNK/p38 MAPK signaling
Colorectal cancer (CRC) remains a major global cause of cancer-related mortality, lacking effective biomarkers and therapeutic targets. Revealing the...
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The function of mitochondrial regulator LRPPRC in Aedes aegypti and its potential for mosquito control
The yellow fever mosquito, Aedes aegypti , affects the health of millions of people by transmitting arboviruses that cause multiple diseases. Since...
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LMO2 promotes the development of AML through interaction with transcription co-regulator LDB1
One of the characteristics of leukemia is that it contains multiple rearrangements of signal transduction genes and overexpression of non-mutant...
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UV-B Radiation and Crop Growth
This book is an inclusive collection of topics on research on UVB for its impact on plants with a focus on its use as an emerging technology for crop...
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The recombination regulator RecX negatively regulates heat-stable antifungal factor (HSAF) biosynthesis in Lysobacter enzymogenes
Bacteria often use multiple transcription factors to regulate specific biological processes. Biosynthesis of heat-stable antifungal factor (HSAF) is...
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Differential expression and cross-correlation between global regulator and pho regulon genes involved in decision-making under phosphate stress
The differential gene expression under phosphate stress conditions leads to cross-talk between the global regulator, pho regulon, and metabolic...
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Genome-Wide Characterization of Cytokinin Response Regulator in Grape and Expression Analyses during Berry Set Process
AbstractCytokinin response regulators (RRs) are a family of transcription factors, which function as a signal output of the cytokinin two-component...
