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Genome-wide epigenetic dynamics during postnatal skeletal muscle growth in Hu sheep
Hypertrophy and fiber transformation are two prominent features of postnatal skeletal muscle development. However, the role of epigenetic...
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CRISPRi-seq for genome-wide fitness quantification in bacteria
CRISPR interference (CRISPRi) is a powerful tool to link essential and nonessential genes to specific phenotypes and to explore their functions. Here...
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Multi-model genome-wide association study on key organic naked barley agronomic, phenological, diseases, and grain quality traits
The study objective was to assess the potential benefits of using genomic tools in organic plant breeding programs to enhance selection efficiency. A...
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Perspectives and recent progress of genome-wide association studies (GWAS) in fruits
BackgroundEarlier next-generation sequencing technologies are being vastly used to explore, administer, and investigate the gene space with accurate...
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Identification of candidate genes and favourable haplotypes for yield traits in rice based on a genome-wide association study
The key to food security is increasing rice yield. Therefore, we performed a genome-wide association study (GWAS) to analyse and identify the effects...
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Genome-wide identification of the geranylgeranyl pyrophosphate synthase (GGPS) gene family involved in chlorophyll synthesis in cotton
BackgroundGeranylgeranyl pyrophosphate synthase (GGPS) is a structural enzyme of the terpene biosynthesis pathway that is involved in regulating...
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Genetic dissection of resistance to gray leaf spot by genome-wide association study in a multi-parent maize population
BackgroundUnderstanding the genetic mechanisms underlying gray leaf spot (GLS) resistance in maize is crucial for breeding GLS-resistant inbred lines...
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Genome wide association map** of yield and various desirable agronomic traits in Rice
BackgroundRice ( Oryza sativa L.) is one of the staple foods worldwide. To feed the growing population, the improvement of rice cultivars is...
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Genetic diversity and genome-wide association study of 13 agronomic traits in 977 Beta vulgaris L. germplasms
BackgroundSugar beet ( Beta vulgaris L.) is an economically essential sugar crop worldwide. Its agronomic traits are highly diverse and...
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Genome-Wide Analysis of DREB Genes in Sugar Beet and Their Potential Functions in Response to Drought Stress
Sugar beet ( Beta vulgaris L) is an important sugar and cash crop, but its production is often severely affected by drought. Dehydration-responsive...
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Genome-wide selective signatures mining the candidate genes for egg laying in goose
BackgroundImproving the egg production of goose is a crucial goal of breeding, because genetics is the key factor affecting egg production. Thus, we...
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Genome-Wide CRISPR Screening to Identify Mammalian Factors that Regulate Intron Retention
Intron retention (IR) regulates gene expression to control fundamental biological processes like metabolism, differentiation, and cell cycle. Despite...
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Identification of fusarium head blight resistance markers in a genome-wide association study of CIMMYT spring synthetic hexaploid derived wheat lines
Fusarium head blight (FHB), caused by Fusarium graminearum , is one of the most destructive wheat diseases worldwide. FHB infection can dramatically...
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Genome-wide sequencing identifies a thermal-tolerance related synonymous mutation in the mussel, Mytilisepta virgata
The roles of synonymous mutations for adapting to stressful thermal environments are of fundamental biological and ecological interests but poorly...
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Genome-wide association studies reveal novel loci for resistance to groundnut rosette disease in the African core groundnut collection
Key messageWe identified markers associated with GRD resistance after screening an Africa-wide core collection across three seasons in Uganda
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Genome wide association study on development and evolution of glutinous rice
BackgroundGlutinous rice as a special endosperm type is consumed as a staple food in East Asian countries by consumers’ preference. Genetic studies...
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Identification of novel loci associated with starch content in maize kernels by a genome-wide association study using an enlarged SNP panel
Starch is a major component of cereals, comprising over 70% of dry weight. It serves as a primary carbon source for humans and animals. In addition,...
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Genome-Wide Resources for Genetic Locus Discovery and Gene Functional Analysis in Wheat
Future wheat production faces considerable challenges, such as how to ensure on-farm yield gains across agricultural environments that are...
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Phenotypic screen and transcriptomics approach complement each other in functional genomics of defensive stink gland physiology
BackgroundFunctional genomics uses unbiased systematic genome-wide gene disruption or analyzes natural variations such as gene expression profiles of...
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Surfaceome CRISPR screen identifies OLFML3 as a rhinovirus-inducible IFN antagonist
BackgroundRhinoviruses (RVs) cause more than half of common colds and, in some cases, more severe diseases. Functional genomics analyses of RVs using...
