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Mitochondrial complex I inhibition triggers NAD+-independent glucose oxidation via successive NADPH formation, “futile” fatty acid cycling, and FADH2 oxidation
Inhibition of mitochondrial complex I (NADH dehydrogenase) is the primary mechanism of the antidiabetic drug metformin and various unrelated natural...
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Comprehensive Evaluation of the Relationships Between Grape Skin Color/Ripening Time and Antioxidative Capacity, Some Phytochemicals, and Fatty Acid Compositions of Their Seeds
It has been proven that grapes, which are widely cultivated around the world, have positive health effects. However, the phytochemical composition of...
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Amino acid profile, physico-chemical properties and fatty acids composition of some fruit seed kernels after detoxification
BackgroundThe use of food processing wastes and by-products, as well as the under-utilization of agricultural products, have recently received...
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The microprotein encoded by exosomal lncAKR1C2 promotes gastric cancer lymph node metastasis by regulating fatty acid metabolism
Lymph node metastasis (LNM) is the prominent route of gastric cancer dissemination, and usually leads to tumor progression and a dismal prognosis of...
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Characterization of the Ayran Made with Commercial Probiotic Cultures for Fatty Acids, Cholesterol, Folic Acid Levels, and Anti-Oxidative Potential
Ayran is a salted drinkable fermented milk food which consumed in many countries around the world. In this study, some chemical parameters were...
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IKBA phosphorylation governs human sperm motility through ACC-mediated fatty acid beta-oxidation
The nuclear factor-κB (NF-κB) signaling pathway regulates specific immunological responses and controls a wide range of physiological processes....
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Intestinal Fatty Acid-Binding Protein Gene (I-FABP) in Golden Pompano Trachinotus ovatus Larvae
Fatty acid-binding proteins (FABPs) belong to the multigene family with 14–16 kDa molecular mass and have the function of binding long-chain fatty...
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Structural characteristics of alpha-fetoprotein, including N-glycosylation, metal ion and fatty acid binding sites
Alpha-fetoprotein (AFP), a serum glycoprotein, is expressed during embryonic development and the pathogenesis of liver cancer. It serves as a...
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Fern Fatty Acids: From Diversity to Dietary Value
Fatty acids are essential components of all living cells and play vital functions in plant and animal organisms. Literature data demonstrate a...
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A novel LGALS1-depended and immune-associated fatty acid metabolism risk model in acute myeloid leukemia stem cells
Leukemia stem cells (LSCs) are recognized as the root cause of leukemia initiation, relapse, and drug resistance. Lipid species are highly abundant...
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Genome-wide association study reveals useful QTL and genes controlling the fatty acid composition in rice bran oil using Vietnamese rice landraces
In rice ( Oryza sativa L.), rice bran contains valuable nutritional constituents, such as high unsaturated fat content, tocotrienols, inositol,...
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Fatty acid desaturases (FADs) modulate multiple lipid metabolism pathways to improve plant resistance
BackgroundBiological and abiotic stresses such as salt, extreme temperatures, and pests and diseases place major constraints on plant growth and crop...
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Sustainable Production of Diatom-Based Omega-3 Fatty Acids
Diatoms constitute a prominent group of phytoplankton characterized by their siliceous cell wall. They account for 20–25% of oxygen release and...
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A mediation analysis of the role of total free fatty acids on pertinence of gut microbiota composition and cognitive function in late life depression
BackgroundExtensive evidence demonstrates correlations among gut microbiota, lipid metabolism and cognitive function. However, there is still a lack...
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Exogenous Melatonin Modulated Drought Stress by Regulating Physio-Biochemical Attributes and Fatty acid Profile of Sweet Cherry (Prunus avium L.)
Melatonin has been widely used to modulate the deleterious effects of drought stress on plant growth and productivity. The purpose of the current...
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Use of mixtures of algal and vegetable oils as fish oil replacers in Asian seabass (Lates calcarifer) feeds and their effects on growth, digestive enzymes, immune biomarkers, fatty acid profiles, and expression of genes involved in fatty acid biosynthesis
An experiment was conducted to assess the potential use of algal oil (AO) and vegetable (soya and palm oil; 1:1) oil (VO) mixtures as replacers for...
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Fatty acid composition of oil crops: genetics and genetic engineering
Vegetable oils are important components of the human diet, and are also actively used for industrial and cosmetic purposes and as biofuels. The scope...
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Fatty acid amide hydrolase drives adult mammary gland development by promoting luminal cell differentiation
Mammary gland development occurs primarily in adulthood, undergoing extensive expansion during puberty followed by cycles of functional...
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Dietary feed nanozeolite, Pediococcus, and medium-chain fatty acid enhanced growth performance and transcription of growth-related gene of Nile tilapia (Oreochromis niloticus)
The current trial was designed to evaluate the positive impacts of different feed additives singly or in combination on the growth performance,...
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Overexpression of ZNF488 supports pancreatic cancer cell proliferation and tumorigenesis through inhibition of ferroptosis via regulating SCD1-mediated unsaturated fatty acid metabolism
BackgroundPancreatic cancer is a malignancy with high mortality. Once diagnosed, effective treatment strategies are limited and the five-year...
