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A New Approach to Release Insoluble Curcumin into DU-145 Human Prostate Cancer Cells Through Biodegradable Polymeric Nanocarriers with Apoptosis Induction and Metastasis Inhibition
AbstractObjective: Curcumin (C 21 H 20 O 6 , CUR) is the most abundant compound in turmeric (Curcuma longa), which had antioxidant, anti-cancer and...
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Association Between the Blood Copper-Zinc (Cu/Zn) Ratio and Anemia in Patients Undergoing Maintenance Hemodialysis
Copper (Cu) and zinc (Zn) imbalances are common in dialysis patients. This study aimed to investigate the relationship between the blood Cu/Zn ratio...
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Optimization of xylanase production by Pichia kudriavzevii and Candida tropicalis isolated from the wood product workshop
Enzymatic compounds can be found abundantly and provide numerous advantages in microbial organisms. Xylanases are used in various pharmaceutical,...
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High Blood Cu/Zn Ratio is Associated with Nutritional Risk in Patients Undergoing Maintenance Hemodialysis
Patients undergoing maintenance hemodialysis (MHD) are at risk of an imbalance of copper and zinc homeostasis. We hypothesized that there is an...
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Bone marrow mesenchymal stem cell-derived exosomal microRNA-381-3p alleviates vascular calcification in chronic kidney disease by targeting NFAT5
Vascular calcification (VC) is a significant complication of chronic kidney disease (CKD) and cellular apoptosis is one of the intricate mechanisms...
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Production and Isolation of the Candida Species Biofilm Extracellular Matrix
The extracellular matrix (ECM) is a dynamic structure comprising of all four classes of macromolecules. In the biofilm setting, this matrix is key to...
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Microgravity crystallization of perdeuterated tryptophan synthase for neutron diffraction
Biologically active vitamin B 6 -derivative pyridoxal 5′-phosphate (PLP) is an essential cofactor in amino acid metabolic pathways. PLP-dependent...
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Reconstitution of Detergent-Solubilized Membrane Proteins into Proteoliposomes and Nanodiscs for Functional and Structural Studies
Reconstitution of detergent-solubilized membrane proteins into phospholipid bilayers allows for functional and structural studies under...
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The Production of Soluble Human Gamma Interferon in the Escherichia coli Expression System with a Decrease in Cultivation Temperature
A recombinant strain for producing human gamma interferon (IFN-γ) E. coli BL 21/pET-IFN-γ was constructed to provide a high level of its expression....
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In vitro assembly of chimeric virus-like particles composed of a porcine circovirus 2b capsid protein and a B-cell epitope of infectious bursal disease virus
ObjectivesTo develop a method for in vitro assembly of recombinant proteins expressed in E. coli into chimeric virus-like particles (cVLPs).
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Partitioning Milk Constituents
This chapter discusses applications of dialysis, ultrafiltration, ultracentrifugation, milk coagulation reactions and precipitation methods for...
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Construction of a prediction model for drug removal rate in hemodialysis based on chemical structures
AbstractIn designing drug dosing for hemodialysis patients, the removal rate (RR) of the drug by hemodialysis is important. However, acquiring the RR...
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Non-high-density lipoprotein cholesterol may predict the cardio-cerebrovascular risk in patients on maintenance hemodialysis
BackgroundNon-high-density lipoprotein cholesterol (non-HDL-C) may be an independent risk factor for cardio-cerebrovascular disease (CVD); however,...
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PPARγ alleviates peritoneal fibrosis progression along with promoting GLUT1 expression and suppressing peritoneal mesothelial cell proliferation
ObjectivePeritoneal fibrosis (PF) is commonly induced by bioincompatible dialysate exposure during peritoneal dialysis, but the underlying mechanisms...
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Self-assembly of smooth muscle myosin filaments: adaptation of filament length by telokin and Mg·ATP
The contractile apparatus of smooth muscle is malleable to accommodate stress and strain exerted on the muscle cell and to maintain optimal...
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Proteomic signature associated with chronic kidney disease (CKD) progression identified by data-independent acquisition mass spectrometry
BackgroundHalting progression of chronic kidney disease (CKD) to established end stage kidney disease is a major goal of global health research. The...
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Improved anti-biofilm activity and long-lasting effects of novel serratiopeptidase immobilized on cellulose nanofibers
AbstractToday, enzymatic treatment is a progressive field in combating biofilm producing pathogens. In this regard, serratiopeptidase, a medicinally...
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Effects of uremic toxins on hippocampal synaptic transmission: implication for neurodegeneration in chronic kidney disease
Patients affected by chronic kidney disease (CKD) have an increased risk of develo** cognitive impairment. The cause of mental health disorders in...
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Calciprotein Particle Synthesis Strategy Determines In Vitro Calcification Potential
Circulating calciprotein particles (CPP), colloids of calcium, phosphate and proteins, were identified as potential drivers of the calcification...
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Associations Between Surrogates of Skeletal Muscle Mass and History of Bone Fracture in Patients with Chronic Kidney Disease: The Fukuoka Kidney disease Registry (FKR) Study
Patients with chronic kidney disease (CKD) are at increased risks of both sarcopenia and fragility fractures. However, information on the association...
