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The Third International Genomic Medicine Conference (3rd IGMC, 2015): overall activities and outcome highlights
The Third International Genomic Medicine Conference (3 rd IGMC) was organised by the Centre of Excellence in Genomic Medicine Research (CEGMR) at the...
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Impairment of IGF2 gene expression in prostate cancer is triggered by epigenetic dysregulation of IGF2-DMR0 and its interaction with KLF4
BackgroundHuman cancer cells often exhibit impaired IGF2 expression and the underlying mechanisms are multifaceted and complex. Besides the...
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Di-2-ethylhexyl phthalate induced oxidative damage involving FasL-associated apoptotic pathway in mouse spermatogenic GC-2spd cells
Di-2-ethylhexyl phthalate (DEHP) which belongs to phthalatic-acid esters, is a kind of harmful, global environmental pollutants. It is a known...
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Analysis of the lifetime and culling reasons for AI boars
BackgroundThe aim of the study was to analyze the lifetime and culling reasons for boars used in insemination centers (AI centers).
Methods ...
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Immunohistochemical verification of kisspeptins and their receptor in human fetal organs during prenatal development
Kisspeptins (KPs) and their receptor (KISS1R) play an important role in many physiological processes in the body, such as sexual maturation,...
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Counting Sperm Numbers
Selection of the best ejaculate from the donor species depends greatly on precise calculation of the concentration of the live sperm cells. Different...
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Spermatogenesis parameters and testosterone production at puberty as predictors of testicular functional activity in mice (Mus musculus)
The aim of this study was to investigate fertility-associated parameters of spermatogenesis and androgenic status in male laboratory mice at puberty...
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Estimating Metabolic Activity of Spermatozoa
The motility of live spermatozoa indicating energy requirement and thus presence of intrinsic metabolic pathways in the cell has led researchers to...
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The toxic effects of trace elements on male reproductive health
The review covers the data on the toxic effects of trace elements on the male reproductive system. The basic pathogenetic mechanisms of male...
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The influence of mast cells on reparative regeneration of tissues characterized by various degrees of immune privilege
Tissues characterized by various degrees of immune privilege are thought to differ in repair processes. This circumstance may be due to mast cells...
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Antioxidant efficiency of lycopene on oxidative stress - induced damage in bovine spermatozoa
BackgroundLycopene (LYC) is a natural carotenoid with powerful reactive oxygen species (ROS) scavenging activities. The aim of this study was to...
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Comprehensive analysis of histone post-translational modifications in mouse and human male germ cells
BackgroundDuring the process of spermatogenesis, male germ cells undergo dramatic chromatin reorganization, whereby most histones are replaced by...
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Molecular and cellular characteristics of human and non-human primate multipotent stromal cells from the amnion and bone marrow during long term culture
IntroductionMultipotent stromal cells (MSCs) are among the key candidates in regenerative medicine. However variety of MSC sources and general...
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Evaluation of thermal comfort, physiological, hematological, and seminal features of buffalo bulls in an artificial insemination station in a tropical environment
This study aimed to assess the variation over time in thermal comfort indices and the behavior of physiological parameters related to thermolysis,...
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Comparative proteomic network signatures in seminal plasma of infertile men as a function of reactive oxygen species
BackgroundReactive oxygen species (ROS) plays a major role in the pathology of male infertility. It is an independent biomarker of sperm function....
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Experimental evidence of proliferation and reproduction of highly differentiated Sertoli cells
The main results of studies regarding the biology of Sertoli cells under various experimental conditions are considered. Possible potential...
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Relationship between the andrological status of adolescents and the anthropometric and hormonal parameters
The relationship between the andrological status and the anthropometric and hormonal characteristics was studied to reveal the age-related features...
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Impact of precise modulation of reactive oxygen species levels on spermatozoa proteins in infertile men
BackgroundElevated levels of reactive oxygen species (ROS) are detected in 25% to 80% of infertile men. They are involved in the pathology of male...
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Evaluation of mesenchymal stem cells in treatment of infertility in male rats
IntroductionThe present study aimed to elucidate the therapeutic effects of mesenchymal stem cells (MSCs) derived from the bone marrow of rats (BM)...
