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Periodontitis-level butyrate-induced ferroptosis in periodontal ligament fibroblasts by activation of ferritinophagy
Loss of periodontal ligament fibroblasts (PDLFs) is one critical issue for regenerating lost periodontal tissues. A wide variety of regulated cell...
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Novel Phocaeicola Strain Ameliorates Dextran Sulfate Sodium-induced Colitis in Mice
Previously, we isolated a novel Phocaeicola strain, Phocaeicola faecalis FXJYN30E22, from the feces of a healthy human from China. Metagenomic...
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Comparison of the effect of sodium bicarbonate, sodium sesquicarbonate, and zeolite as rumen buffers on apparent digestibility, growth performance, and rumen fermentation parameters of Arabi lambs
The current research was conducted to compare the effect of various buffers or alkalizers in Arabi lambs and find new and less expensive buffering...
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Butyrate’s (a short-chain fatty acid) microbial synthesis, absorption, and preventive roles against colorectal and lung cancer
Butyrate, a short-chain fatty acid (SCFA) produced by bacterial fermentation of fiber in the colon, is a source of energy for colonocytes. Butyrate...
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Xylanase improves the intestinal barrier function of Nile tilapia (Oreochromis niloticus) fed with soybean (Glycine max) meal
BackgroundSoybean ( Glycine max ) meal is one of the important protein sources for fish, but the non-starch polysaccharides (NSP) in soybean meal...
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Dietary resveratrol attenuation of intestinal inflammation and oxidative damage is linked to the alteration of gut microbiota and butyrate in piglets challenged with deoxynivalenol
BackgroundDeoxynivalenol (DON) is a widespread mycotoxin that induces intestinal inflammation and oxidative stress in humans and animals. Resveratrol...
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Ruminal modulator additive effect of Stryphnodendron rotundifolium bark in feedlot lambs
The study aimed to evaluate the inclusion effects of Stryphnodendron rotundifolium (barbatimão) extracts in substitution of the lasalocid sodium on...
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Open microbiome dominated by Clostridium and Eubacterium converts methanol into i-butyrate and n-butyrate
Isobutyrate ( i -butyrate) is a versatile platform chemical, whose acid form is used as a precursor of plastic and emulsifier. It can be produced...
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Performance, nutritional behavior, and carcass characteristics of feedlot lambs fed diets with non-forage fiber source or sodium bicarbonate
The study was carried out to evaluate the effect of sodium bicarbonate (SB) supplementation in diets and compare its chemical effect with the fiber...
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Potassium sodium hydrogen citrate intervention on gut microbiota and clinical features in uric acid stone patients
AbstractThe high recurrence rate of renal uric acid stone (UAS) poses a significant challenge for urologists, and potassium sodium hydrogen citrate...
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5-Aminosalicylic acid ameliorates dextran sulfate sodium-induced colitis in mice by modulating gut microbiota and bile acid metabolism
Colitis develops via the convergence of environmental, microbial, immunological, and genetic factors. The medicine 5-aminosalicylic acid (5-ASA) is...
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Exploring the potential of epigenetic chemicals to increase metabolite production in the dinoflagellate microalga Amphidinium carterae
This study explores the use of chemical epigenetic modifiers to enhance the production of bioactive molecules in the dinoflagellate Amphidinium...
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Bioinformatics and metabolic flux analysis highlight a new mechanism involved in lactate oxidation in Clostridium tyrobutyricum
Climate change and environmental issues compel us to find alternatives to the production of molecules of interest from petrochemistry. This study...
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Attenuation of Hyperglycemia in Diabetic Rats Assisted by Immobilized Probiotic in Sodium Alginate
Diabetes mellitus type 2 (DM2) is the most common chronic disease worldwide, characterized mainly by increased glucose concentration in the blood and...
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Preliminary Exposure to Histone Deacetylase Inhibitors Changes the Direction of Human iPSCs’ Differentiation with the Formation of Cardiospheres Instead of Skin Organoids
AbstractPluripotent stem cells (PSCs) are a unique cell type that can differentiate into all cell types in the body. In PSC culture, subpopulations...
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The impact of antimicrobial food additives and sweeteners on the growth and metabolite production of gut bacteria
Metabolic disorders caused by the imbalance of gut microbiota have been associated with the consumption of processed foods. Thus, this study aimed to...
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Contribution of histone acetylation to the serotonin-mediated long-term synaptic plasticity in terrestrial snails
Serotonin plays a decisive role in long-term synaptic plasticity and long-term memory in mollusks. Previously, we demonstrated that histone...
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Transcriptomics and physiology reveal the mechanism of potassium indole-3-butyrate (IBAK) mediating rice resistance to salt stress
BackgroundIBAK, as a plant growth regulator, has broad application prospects in improving crop resistance to abiotic stress.
ResultsIn this study,...
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Short-chain fatty acids in diseases
Short-chain fatty acids (SCFAs) are the main metabolites produced by bacterial fermentation of dietary fibre in the gastrointestinal tract. The...
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Sodium butyrate induces genotoxic stress in function of photoperiod variations and differentially modulates the expression of genes involved in chromatin modification and DNA repair in Petunia hybrida seedlings
Main conclusionSodium butyrate applied to Petunia hybrida seeds under a long-day photoperiod has a negative impact (reduced seedling length,...